Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacT-ataR/DUF1778(antitoxin)
Location 1359448..1360202 Replicon chromosome
Accession NZ_CP072932
Organism Xylella fastidiosa subsp. multiplex strain BB08-1

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag KBP48_RS06270 Protein ID WP_021358673.1
Coordinates 1359448..1359927 (-) Length 160 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag KBP48_RS06275 Protein ID WP_004085396.1
Coordinates 1359930..1360202 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KBP48_RS06250 (KBP48_06250) 1354703..1356139 + 1437 WP_140189574.1 exodeoxyribonuclease I -
KBP48_RS06255 (KBP48_06255) 1356136..1356822 + 687 WP_140189573.1 TIGR02453 family protein -
KBP48_RS06260 (KBP48_06260) 1356953..1357951 + 999 WP_004085391.1 MBL fold metallo-hydrolase -
KBP48_RS06265 (KBP48_06265) 1357917..1359111 + 1195 Protein_1228 DUF5710 domain-containing protein -
KBP48_RS06270 (KBP48_06270) 1359448..1359927 - 480 WP_021358673.1 GNAT family N-acetyltransferase Toxin
KBP48_RS06275 (KBP48_06275) 1359930..1360202 - 273 WP_004085396.1 DUF1778 domain-containing protein Antitoxin
KBP48_RS11480 1360492..1361136 - 645 WP_247644575.1 AEC family transporter -
KBP48_RS06285 (KBP48_06285) 1361575..1362193 + 619 Protein_1232 IS607 family transposase -
KBP48_RS06290 (KBP48_06290) 1362388..1364454 + 2067 WP_080654481.1 glycoside hydrolase family 3 N-terminal domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(33-146)

Antitoxin

Vibrio phage ICP1, Orf50

(3-85)


Sequences

Toxin        


Download         Length: 160 a.a.        Molecular weight: 17645.42 Da        Isoelectric Point: 9.9283

>T199221 WP_021358673.1 NZ_CP072932:c1359927-1359448 [Xylella fastidiosa subsp. multiplex]
MQISTPHSLTAAHRLDEFNCGEPSLDDWLKRRALTNHLNGASRTFVVIDANQYVLGYYALAAGAVAHQEATRAIRRNMPD
PVPVMVLGRLAVDTRAQGIKLGAALLKDTVTRVQSIAENAGVRALVVHALNERAKQFYEYYGFRASPMHLMTLMLPIKF

Download         Length: 480 bp

>T199221 NZ_CP097245:c1099545-1099303 [Leptospira santarosai]
ATGAAGGTCTCGGTTGTAAAAATAGGTAATTCTAAAGGTATTCGAATACCCAAAGCGGTTTTAGAAGAATGTCACATTGA
AGACGAAGTAGATTTGCTAATCAATAATAACAAACTAATCGTCGTACCGCTAAAATCAAAACCAAGAGAAGGATGGGAAA
AACAATTTAAGACAATGTCGTCTAATAAAGATGATAAATTACTTATTCCTGATTCAATAGATTTGTCAGATTGGGAATGG
TGA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10264.77 Da        Isoelectric Point: 5.0488

>AT199221 WP_004085396.1 NZ_CP072932:c1360202-1359930 [Xylella fastidiosa subsp. multiplex]
MRDASINLRAMPEQRDLIDQAANLLGKNRSDFMLEAACERAKAIILDQVFFNLDEERFRQFTVLLNAPQDTNPGLNRLMA
IKAPWSISNT

Download         Length: 273 bp

>AT199221 NZ_CP097245:c1099303-1098980 [Leptospira santarosai]
ATGGTGATTGCCCAATACGAAGTATATTTGATAAATTTAGATCCAACGATCGGATATGAGATTAAAAAATCAAGGCCCTG
TGTAATAATTTCGCCTAATGAAATGAATAAAACGATTGGAACGATTATTATCGCACCAATGACGACCAAATCTAGAACTT
ATCCGACTAGGATTGAATTAACATTTCAAGGAAAGAAAGGTTGGATTGTGTTAGATCAAATTCGAACCGTAGATAAGGTT
CGCTTGATAAAAAAGTTGGGTAAAATAGATTCTAAAATCAGTAATCAATTGAAATCGATTATAAAAGAAATGTTGGTTGA
CTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References