Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | pasABC/RelE-HTH |
| Location | 1031061..1031538 | Replicon | chromosome |
| Accession | NZ_CP072932 | ||
| Organism | Xylella fastidiosa subsp. multiplex strain BB08-1 | ||
Toxin (Protein)
| Gene name | pasB | Uniprot ID | - |
| Locus tag | KBP48_RS04705 | Protein ID | WP_004087087.1 |
| Coordinates | 1031061..1031327 (-) | Length | 89 a.a. |
Antitoxin (Protein)
| Gene name | pasA | Uniprot ID | A0A7G7TPD2 |
| Locus tag | KBP48_RS04710 | Protein ID | WP_004091377.1 |
| Coordinates | 1031311..1031538 (-) | Length | 76 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| KBP48_RS04675 (KBP48_04675) | 1026486..1027694 | + | 1209 | WP_038211641.1 | DUF2213 domain-containing protein | - |
| KBP48_RS04680 (KBP48_04680) | 1027704..1028186 | + | 483 | WP_140189638.1 | hypothetical protein | - |
| KBP48_RS04685 (KBP48_04685) | 1028196..1028534 | + | 339 | WP_140161927.1 | hypothetical protein | - |
| KBP48_RS04695 (KBP48_04695) | 1028588..1029013 | + | 426 | WP_234545923.1 | putative phage tail assembly chaperone | - |
| KBP48_RS04700 (KBP48_04700) | 1029410..1031050 | + | 1641 | WP_247644634.1 | phage tail tape measure protein | - |
| KBP48_RS04705 (KBP48_04705) | 1031061..1031327 | - | 267 | WP_004087087.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| KBP48_RS04710 (KBP48_04710) | 1031311..1031538 | - | 228 | WP_004091377.1 | DUF6290 family protein | Antitoxin |
| KBP48_RS04715 (KBP48_04715) | 1031649..1032419 | + | 771 | WP_140160955.1 | hypothetical protein | - |
| KBP48_RS04720 (KBP48_04720) | 1032419..1032736 | + | 318 | WP_012382585.1 | hypothetical protein | - |
| KBP48_RS04725 (KBP48_04725) | 1032733..1033563 | + | 831 | WP_038230303.1 | hypothetical protein | - |
| KBP48_RS04730 (KBP48_04730) | 1033560..1034201 | + | 642 | WP_140189635.1 | Gp138 family membrane-puncturing spike protein | - |
| KBP48_RS04735 (KBP48_04735) | 1034198..1034551 | + | 354 | WP_020851652.1 | hypothetical protein | - |
| KBP48_RS04740 (KBP48_04740) | 1034562..1034867 | - | 306 | WP_038211623.1 | putative addiction module antidote protein | - |
| KBP48_RS04745 (KBP48_04745) | 1034871..1035167 | - | 297 | WP_004089252.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| KBP48_RS04750 (KBP48_04750) | 1035266..1036411 | + | 1146 | WP_140189634.1 | baseplate J/gp47 family protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 1017991..1038216 | 20225 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 89 a.a. Molecular weight: 10207.80 Da Isoelectric Point: 10.3398
>T199218 WP_004087087.1 NZ_CP072932:c1031327-1031061 [Xylella fastidiosa subsp. multiplex]
MAWTIDYTDTAKQQLRKLDKHMARRIVDFMDERIAGLENPRSSGKALTGPLGGFWRYRVGDFRVVCDIQDSVLRVLVVRV
GHRGEIYR
MAWTIDYTDTAKQQLRKLDKHMARRIVDFMDERIAGLENPRSSGKALTGPLGGFWRYRVGDFRVVCDIQDSVLRVLVVRV
GHRGEIYR
Download Length: 267 bp
>T199218 NZ_CP097240:12730-13146 [Klebsiella pneumoniae]
GTGAACAAGACCTATATGCTCGACACCTGTATCTGCTCGTTCATCATGCGCGAGCAGCCGGAAGCCGTCCTGAAGCGCCT
GGAGCAGGCGGTGCTGCGCGGCCAGCGCATCGTTGTCTCGGCCATCACTTATTCTGAAATGCGCTTCGGGGCCACCGGCC
CGAAGGCCTCCCCGCGCCACGTCGAGCTGGTCGACGCGTTCTGCGCCCGCCTCGATGCCATCCTGCCCTGGGATCGCGCT
GCGGTGGACGCCACCACGGAGATTAAGGTGGCGCTGCGAATGGCCGGGACGCCGATCGGCCCGAACGACACGGCCATTGC
CGGGCACGCCATCGCCGCCGGTGCCGTGCTGGTGACGAATAATACGCGGGAATTTGAGCGGGTACCGGGTCTTGTGCTGG
AAGACTGGGTAAGATAA
GTGAACAAGACCTATATGCTCGACACCTGTATCTGCTCGTTCATCATGCGCGAGCAGCCGGAAGCCGTCCTGAAGCGCCT
GGAGCAGGCGGTGCTGCGCGGCCAGCGCATCGTTGTCTCGGCCATCACTTATTCTGAAATGCGCTTCGGGGCCACCGGCC
CGAAGGCCTCCCCGCGCCACGTCGAGCTGGTCGACGCGTTCTGCGCCCGCCTCGATGCCATCCTGCCCTGGGATCGCGCT
GCGGTGGACGCCACCACGGAGATTAAGGTGGCGCTGCGAATGGCCGGGACGCCGATCGGCCCGAACGACACGGCCATTGC
CGGGCACGCCATCGCCGCCGGTGCCGTGCTGGTGACGAATAATACGCGGGAATTTGAGCGGGTACCGGGTCTTGTGCTGG
AAGACTGGGTAAGATAA
Antitoxin
Download Length: 76 a.a. Molecular weight: 8615.63 Da Isoelectric Point: 5.0958
>AT199218 WP_004091377.1 NZ_CP072932:c1031538-1031311 [Xylella fastidiosa subsp. multiplex]
MATSIRLSPEMEQRLNSLASHTGRTKAYYLREIIEHGIEEMEDYYLAADVLERVRHGQEQVHSAADVRKTLGLDD
MATSIRLSPEMEQRLNSLASHTGRTKAYYLREIIEHGIEEMEDYYLAADVLERVRHGQEQVHSAADVRKTLGLDD
Download Length: 228 bp
>AT199218 NZ_CP097240:12503-12733 [Klebsiella pneumoniae]
ATGAGAACTGTATCCATTTTTAAAAACGGCAATAACCGCGCCATTCGTCTGCCCCGCGATCTGGATTTTGAGGGAGTGAG
CGAGCTGGAGATCGTCCGGGAAGGGGACAGCATTATTTTGCGTCCCGTCCGGCCGACCTGGGGCTCGTTCGCGCAGTTCG
AGAAGGCAGACCCGGACTTTATGGCGGAGCGCGAGGACGTTGTCAGCGACGAAGGACGATTTAACCTGTGA
ATGAGAACTGTATCCATTTTTAAAAACGGCAATAACCGCGCCATTCGTCTGCCCCGCGATCTGGATTTTGAGGGAGTGAG
CGAGCTGGAGATCGTCCGGGAAGGGGACAGCATTATTTTGCGTCCCGTCCGGCCGACCTGGGGCTCGTTCGCGCAGTTCG
AGAAGGCAGACCCGGACTTTATGGCGGAGCGCGAGGACGTTGTCAGCGACGAAGGACGATTTAACCTGTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|