Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | vapC-vagC/VapC-VagC |
| Location | 74308..74945 | Replicon | plasmid p6 |
| Accession | NZ_CP072871 | ||
| Organism | Rhizobium sp. NLR16a | ||
Toxin (Protein)
| Gene name | vapC | Uniprot ID | - |
| Locus tag | J7U39_RS30695 | Protein ID | WP_210633779.1 |
| Coordinates | 74544..74945 (+) | Length | 134 a.a. |
Antitoxin (Protein)
| Gene name | vagC | Uniprot ID | - |
| Locus tag | J7U39_RS30690 | Protein ID | WP_210633778.1 |
| Coordinates | 74308..74544 (+) | Length | 79 a.a. |
Genomic Context
Location: 74308..74544 (237 bp)
Type: Antitoxin
Protein ID: WP_210633778.1
Type: Antitoxin
Protein ID: WP_210633778.1
Location: 74544..74945 (402 bp)
Type: Toxin
Protein ID: WP_210633779.1
Type: Toxin
Protein ID: WP_210633779.1
Location: 75402..76682 (1281 bp)
Type: Others
Protein ID: WP_210633799.1
Type: Others
Protein ID: WP_210633799.1
Location: 69534..70517 (984 bp)
Type: Others
Protein ID: WP_210633772.1
Type: Others
Protein ID: WP_210633772.1
Location: 70514..71071 (558 bp)
Type: Others
Protein ID: WP_210633774.1
Type: Others
Protein ID: WP_210633774.1
Location: 71275..73677 (2403 bp)
Type: Others
Protein ID: WP_210633775.1
Type: Others
Protein ID: WP_210633775.1
Location: 73842..74093 (252 bp)
Type: Others
Protein ID: WP_210633777.1
Type: Others
Protein ID: WP_210633777.1
Location: 76809..78644 (1836 bp)
Type: Others
Protein ID: WP_210633780.1
Type: Others
Protein ID: WP_210633780.1
Location: 78941..79555 (615 bp)
Type: Others
Protein ID: WP_210633781.1
Type: Others
Protein ID: WP_210633781.1
Location: 79552..79662 (111 bp)
Type: Others
Protein ID: Protein_78
Type: Others
Protein ID: Protein_78
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| J7U39_RS30670 (J7U39_30670) | 69534..70517 | - | 984 | WP_210633772.1 | cytochrome c oxidase subunit II | - |
| J7U39_RS30675 (J7U39_30675) | 70514..71071 | - | 558 | WP_210633774.1 | cytochrome c | - |
| J7U39_RS30680 (J7U39_30680) | 71275..73677 | - | 2403 | WP_210633775.1 | FdhF/YdeP family oxidoreductase | - |
| J7U39_RS30685 (J7U39_30685) | 73842..74093 | - | 252 | WP_210633777.1 | hypothetical protein | - |
| J7U39_RS30690 (J7U39_30690) | 74308..74544 | + | 237 | WP_210633778.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin |
| J7U39_RS30695 (J7U39_30695) | 74544..74945 | + | 402 | WP_210633779.1 | type II toxin-antitoxin system VapC family toxin | Toxin |
| J7U39_RS30700 (J7U39_30700) | 75402..76682 | + | 1281 | WP_210633799.1 | DUF3422 domain-containing protein | - |
| J7U39_RS30705 (J7U39_30705) | 76809..78644 | - | 1836 | WP_210633780.1 | HAMP domain-containing methyl-accepting chemotaxis protein | - |
| J7U39_RS30710 (J7U39_30710) | 78941..79555 | - | 615 | WP_210633781.1 | thiamine phosphate synthase | - |
| J7U39_RS30715 (J7U39_30715) | 79552..79662 | - | 111 | Protein_78 | thiazole synthase | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Non-Mobilizable plasmid | - | - | 1..197677 | 197677 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 134 a.a. Molecular weight: 15199.51 Da Isoelectric Point: 6.4641
>T199063 WP_210633779.1 NZ_CP072871:74544-74945 [Rhizobium sp. NLR16a]
MPLYMLDTNMCIYLMKEQPPQVARRFAQCRVGDVVMSAITFAELEYGVSASKDAERERSNLEYLIEAIPVAPFDSDAARA
YGPLRFATRDRKKDHLDKLIAAHAVSLKAVLVTNNVRDFTVYQDLRVENWLFP
MPLYMLDTNMCIYLMKEQPPQVARRFAQCRVGDVVMSAITFAELEYGVSASKDAERERSNLEYLIEAIPVAPFDSDAARA
YGPLRFATRDRKKDHLDKLIAAHAVSLKAVLVTNNVRDFTVYQDLRVENWLFP
Download Length: 402 bp
>T199063 NZ_CP097170:1136494-1136901 [Escherichia coli]
GTGGTCCTGTGGCAATCTGATCTGCGCGTCTCCTGGCGCGCACAGTGGCTTTCCTTGCTGATCCACGGGCTGGTTGCCGC
TGTTATTTTACTCATGCCCTGGCCGCTCAGTTACACCCCGTTATGGATGGTGTTACTTTCGCTGGTGGTGTTTGATTGCG
TTCGCAGCCAGCGGCGCATTAATGCTCGCCAGGGGGAAATTCGCCTGTTGATGGACGGGCGTTTGCGCTGGCAAGGGCAG
GAGTGGAGCATCGTCAAAGCGCCGTGGATGATTAAGAGCGGCATGATGCTGCGTTTACGTTCTGACAGCGGTAAACGGCA
ACATTTATGGCTGGCAGCCGACAGCATGGACGAAGCCGAATGGCGGGATTTACGGCGGATATTGTTGCAACAAGAGACGC
AAAGATAA
GTGGTCCTGTGGCAATCTGATCTGCGCGTCTCCTGGCGCGCACAGTGGCTTTCCTTGCTGATCCACGGGCTGGTTGCCGC
TGTTATTTTACTCATGCCCTGGCCGCTCAGTTACACCCCGTTATGGATGGTGTTACTTTCGCTGGTGGTGTTTGATTGCG
TTCGCAGCCAGCGGCGCATTAATGCTCGCCAGGGGGAAATTCGCCTGTTGATGGACGGGCGTTTGCGCTGGCAAGGGCAG
GAGTGGAGCATCGTCAAAGCGCCGTGGATGATTAAGAGCGGCATGATGCTGCGTTTACGTTCTGACAGCGGTAAACGGCA
ACATTTATGGCTGGCAGCCGACAGCATGGACGAAGCCGAATGGCGGGATTTACGGCGGATATTGTTGCAACAAGAGACGC
AAAGATAA
Antitoxin
Download Length: 79 a.a. Molecular weight: 8952.07 Da Isoelectric Point: 4.8483
>AT199063 WP_210633778.1 NZ_CP072871:74308-74544 [Rhizobium sp. NLR16a]
MHTTKVFKNGNSQAVRIPADLAYSQTEMELEIERIGDELRIRPLKPSLEGVLARFARFDDSFMAEGRGDQEQAERDRL
MHTTKVFKNGNSQAVRIPADLAYSQTEMELEIERIGDELRIRPLKPSLEGVLARFARFDDSFMAEGRGDQEQAERDRL
Download Length: 237 bp
>AT199063 NZ_CP097170:1136247-1136513 [Escherichia coli]
ATGGACATTAACAACAAAGCCCGCATTCATTGGGCATGCCGCCGTGGTATGCGCGAACTCGATATTTCAATCATGCCGTT
TTTCGAACATGAGTACGACAGCTTAAGCGATGACGAAAAACGCATCTTTATTCGTCTGCTGGAGTGTGACGATCCCGATC
TGTTTAACTGGCTGATGAACCACGGTAAACCGGCCGATGCAGAACTGGAAATGATGGTCCGACTCATCCAGACACGGAAC
CGGGAACGTGGTCCTGTGGCAATCTGA
ATGGACATTAACAACAAAGCCCGCATTCATTGGGCATGCCGCCGTGGTATGCGCGAACTCGATATTTCAATCATGCCGTT
TTTCGAACATGAGTACGACAGCTTAAGCGATGACGAAAAACGCATCTTTATTCGTCTGCTGGAGTGTGACGATCCCGATC
TGTTTAACTGGCTGATGAACCACGGTAAACCGGCCGATGCAGAACTGGAAATGATGGTCCGACTCATCCAGACACGGAAC
CGGGAACGTGGTCCTGTGGCAATCTGA