Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapC-vagC/VapC-VagC
Location 74308..74945 Replicon plasmid p6
Accession NZ_CP072871
Organism Rhizobium sp. NLR16a

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag J7U39_RS30695 Protein ID WP_210633779.1
Coordinates 74544..74945 (+) Length 134 a.a.

Antitoxin (Protein)


Gene name vagC Uniprot ID -
Locus tag J7U39_RS30690 Protein ID WP_210633778.1
Coordinates 74308..74544 (+) Length 79 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J7U39_RS30670 (J7U39_30670) 69534..70517 - 984 WP_210633772.1 cytochrome c oxidase subunit II -
J7U39_RS30675 (J7U39_30675) 70514..71071 - 558 WP_210633774.1 cytochrome c -
J7U39_RS30680 (J7U39_30680) 71275..73677 - 2403 WP_210633775.1 FdhF/YdeP family oxidoreductase -
J7U39_RS30685 (J7U39_30685) 73842..74093 - 252 WP_210633777.1 hypothetical protein -
J7U39_RS30690 (J7U39_30690) 74308..74544 + 237 WP_210633778.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
J7U39_RS30695 (J7U39_30695) 74544..74945 + 402 WP_210633779.1 type II toxin-antitoxin system VapC family toxin Toxin
J7U39_RS30700 (J7U39_30700) 75402..76682 + 1281 WP_210633799.1 DUF3422 domain-containing protein -
J7U39_RS30705 (J7U39_30705) 76809..78644 - 1836 WP_210633780.1 HAMP domain-containing methyl-accepting chemotaxis protein -
J7U39_RS30710 (J7U39_30710) 78941..79555 - 615 WP_210633781.1 thiamine phosphate synthase -
J7U39_RS30715 (J7U39_30715) 79552..79662 - 111 Protein_78 thiazole synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..197677 197677


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-115)

Antitoxin

SpoVT-AbrB domain

(7-46)


Sequences

Toxin        


Download         Length: 134 a.a.        Molecular weight: 15199.51 Da        Isoelectric Point: 6.4641

>T199063 WP_210633779.1 NZ_CP072871:74544-74945 [Rhizobium sp. NLR16a]
MPLYMLDTNMCIYLMKEQPPQVARRFAQCRVGDVVMSAITFAELEYGVSASKDAERERSNLEYLIEAIPVAPFDSDAARA
YGPLRFATRDRKKDHLDKLIAAHAVSLKAVLVTNNVRDFTVYQDLRVENWLFP

Download         Length: 402 bp

>T199063 NZ_CP097170:1136494-1136901 [Escherichia coli]
GTGGTCCTGTGGCAATCTGATCTGCGCGTCTCCTGGCGCGCACAGTGGCTTTCCTTGCTGATCCACGGGCTGGTTGCCGC
TGTTATTTTACTCATGCCCTGGCCGCTCAGTTACACCCCGTTATGGATGGTGTTACTTTCGCTGGTGGTGTTTGATTGCG
TTCGCAGCCAGCGGCGCATTAATGCTCGCCAGGGGGAAATTCGCCTGTTGATGGACGGGCGTTTGCGCTGGCAAGGGCAG
GAGTGGAGCATCGTCAAAGCGCCGTGGATGATTAAGAGCGGCATGATGCTGCGTTTACGTTCTGACAGCGGTAAACGGCA
ACATTTATGGCTGGCAGCCGACAGCATGGACGAAGCCGAATGGCGGGATTTACGGCGGATATTGTTGCAACAAGAGACGC
AAAGATAA

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 8952.07 Da        Isoelectric Point: 4.8483

>AT199063 WP_210633778.1 NZ_CP072871:74308-74544 [Rhizobium sp. NLR16a]
MHTTKVFKNGNSQAVRIPADLAYSQTEMELEIERIGDELRIRPLKPSLEGVLARFARFDDSFMAEGRGDQEQAERDRL

Download         Length: 237 bp

>AT199063 NZ_CP097170:1136247-1136513 [Escherichia coli]
ATGGACATTAACAACAAAGCCCGCATTCATTGGGCATGCCGCCGTGGTATGCGCGAACTCGATATTTCAATCATGCCGTT
TTTCGAACATGAGTACGACAGCTTAAGCGATGACGAAAAACGCATCTTTATTCGTCTGCTGGAGTGTGACGATCCCGATC
TGTTTAACTGGCTGATGAACCACGGTAAACCGGCCGATGCAGAACTGGAAATGATGGTCCGACTCATCCAGACACGGAAC
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References