Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/CC2985(antitoxin)
Location 207853..208400 Replicon plasmid p5
Accession NZ_CP072870
Organism Rhizobium sp. NLR16a

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag J7U39_RS29925 Protein ID WP_210633303.1
Coordinates 208107..208400 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag J7U39_RS29920 Protein ID WP_210633296.1
Coordinates 207853..208107 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J7U39_RS29905 (J7U39_29905) 203897..204910 + 1014 WP_210633291.1 alpha-ketoacid dehydrogenase subunit beta -
J7U39_RS29910 (J7U39_29910) 204914..206158 + 1245 WP_210633293.1 dihydrolipoamide acetyltransferase family protein -
J7U39_RS29915 (J7U39_29915) 206163..207560 + 1398 WP_210633294.1 dihydrolipoyl dehydrogenase -
J7U39_RS29920 (J7U39_29920) 207853..208107 + 255 WP_210633296.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
J7U39_RS29925 (J7U39_29925) 208107..208400 + 294 WP_210633303.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
J7U39_RS29930 (J7U39_29930) 208719..209507 - 789 WP_210633304.1 slipin family protein -
J7U39_RS29935 (J7U39_29935) 209537..210940 - 1404 WP_210633306.1 nodulation protein NfeD -
J7U39_RS32105 211341..212447 + 1107 WP_247241816.1 sensor domain-containing diguanylate cyclase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..290334 290334


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-92)

Antitoxin

Antitoxin ParD

(6-63)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11173.71 Da        Isoelectric Point: 5.5102

>T199062 WP_210633303.1 NZ_CP072870:208107-208400 [Rhizobium sp. NLR16a]
MRFDLSVEAEEDIIAIAEQGVRMFGAAQARQYHDELFTVLDLIAANPRMAREREEISPPVRVHPFKAHLIVYRIEEHGAI
FVIRIRHGHEDWASDPA

Download         Length: 294 bp

>T199062 NZ_CP097170:c951317-950940 [Escherichia coli]
ATGAAAACATTACCTGACACACACGTACGGGAGGCATCGTGCTGCCCGTCTCCCGTCACCATCTGGCAGACACTGCTCAC
CCGACTGTTGGACCAGCATTACGGCCTCACACTGAATGACACACCGTTCGCTGATGAACGTGTGATTGAGCAGCATATTG
AGGCAGGCATTTCACTGTGCAATGCGGTGAACTTTCTCGTTGAAAAATACGCACTGGTACGTACCGACCAGCCGGGATTC
AGCGCCTGTACCCGTTCTCAGTTAATAAACAGTATTGATATCCTCCGGGCCCGCCGGGCAACCGGCCTGATGGCCCGCGA
CAATTACAGAACGGTAAATAACATTACCCTGGGTAAACATCCGGGGGCGAAACAATGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9355.53 Da        Isoelectric Point: 10.1451

>AT199062 WP_210633296.1 NZ_CP072870:207853-208107 [Rhizobium sp. NLR16a]
MATMNVSLPDPMKDWVEAQAKSGRYSNASDYVRDLIRRDQIRSDKVAVMQRFVDDGFKSGIGSRSKDELFAAAVARAETT
RGGR

Download         Length: 255 bp

>AT199062 NZ_CP097170:c951738-951364 [Escherichia coli]
GTGTCAGACACACACCCCGGGACAACGCATCCCGACAACAACAACGACCGCCCCTGGTGGGGGCTCCCCTGCACCGTGAC
GCCCTGTTTCGGGGCACGTCTGGTGCAGGAGGGCAATCAGTTGCATTACCTTGCCGACCGCGCCGGTATCAGGGGGCAGT
TTAGCGACGCGGATGCGTATCATCTGGACCAGGCCTTTCCGCTGCTGATGAAACAACTGGAACTCATGCTCACCAGCGGT
GAACTGAATCCCCGCCATCAGCATACCGTCACGCTGTATGCCAGAGGGCTGACCTGCGAAGCCGACACCCTCGGCAGCTG
TGGTTACGTTTATATGGCTGTTTATCCGACACTGGCACCCGCAACCACCTCATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References