Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VapB
Location 288493..289073 Replicon plasmid p2
Accession NZ_CP072867
Organism Rhizobium sp. NLR16a

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag J7U39_RS23575 Protein ID WP_210632233.1
Coordinates 288493..288876 (-) Length 128 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag J7U39_RS23580 Protein ID WP_210632655.1
Coordinates 288873..289073 (-) Length 67 a.a.

Genomic Context

J7U39_RS23570J7U39_RS23590J7U39_RS23600J7U39_RS23605J7U39_RS23610J7U39_RS23550J7U39_RS23555J7U39_RS23560J7U39_RS23565J7U39_RS23575J7U39_RS23580J7U39_RS23585J7U39_RS23595
Location: 288166..288522 (357 bp)
Type: Others
Protein ID: WP_210632232.1
Location: 289664..290369 (706 bp)
Type: Others
Protein ID: Protein_263
Location: 291316..292023 (708 bp)
Type: Others
Protein ID: WP_210632235.1
Location: 292020..292709 (690 bp)
Type: Others
Protein ID: WP_210632236.1
Location: 292720..293925 (1206 bp)
Type: Others
Protein ID: WP_210632237.1
Location: 284517..286025 (1509 bp)
Type: Others
Protein ID: WP_210632229.1
Location: 286237..287163 (927 bp)
Type: Others
Protein ID: WP_210632230.1
Location: 287269..287690 (422 bp)
Type: Others
Protein ID: Protein_257
Location: 287687..287935 (249 bp)
Type: Others
Protein ID: WP_210632231.1
Location: 288493..288876 (384 bp)
Type: Toxin
Protein ID: WP_210632233.1
Location: 288873..289073 (201 bp)
Type: Antitoxin
Protein ID: WP_210632655.1
Location: 289313..289657 (345 bp)
Type: Others
Protein ID: Protein_262
Location: 290425..291183 (759 bp)
Type: Others
Protein ID: WP_210632234.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
J7U39_RS23550 (J7U39_23550)284517..286025-1509WP_210632229.1alpha-N-arabinofuranosidase-
J7U39_RS23555 (J7U39_23555)286237..287163-927WP_210632230.1helix-turn-helix domain-containing protein-
J7U39_RS23560 (J7U39_23560)287269..287690-422Protein_257type II toxin-antitoxin system VapC family toxin-
J7U39_RS23565 (J7U39_23565)287687..287935-249WP_210632231.1plasmid stabilization protein-
J7U39_RS23570 (J7U39_23570)288166..288522+357WP_210632232.1hypothetical protein-
J7U39_RS23575 (J7U39_23575)288493..288876-384WP_210632233.1type II toxin-antitoxin system VapC family toxinToxin
J7U39_RS23580 (J7U39_23580)288873..289073-201WP_210632655.1type II toxin-antitoxin system VapB family antitoxinAntitoxin
J7U39_RS23585 (J7U39_23585)289313..289657-345Protein_262cytochrome-c peroxidase-
J7U39_RS23590 (J7U39_23590)289664..290369+706Protein_263acid phosphatase-
J7U39_RS23595 (J7U39_23595)290425..291183-759WP_210632234.1IclR family transcriptional regulator-
J7U39_RS23600 (J7U39_23600)291316..292023+708WP_210632235.13-oxoacid CoA-transferase subunit A-
J7U39_RS23605 (J7U39_23605)292020..292709+690WP_210632236.1CoA transferase subunit B-
J7U39_RS23610 (J7U39_23610)292720..293925+1206WP_210632237.13-oxoadipyl-CoA thiolase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideNon-Mobilizable plasmid--1..519704519704


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-112)

Antitoxin

Bacterial antitoxin of type II TA system, VapB

(1-42)


Sequences

Toxin        


Download         Length: 128 a.a.        Molecular weight: 14109.28 Da        Isoelectric Point: 7.4758

>T199059 WP_210632233.1 NZ_CP072867:c288876-288493 [Rhizobium sp. NLR16a]
VILADTSIWIDHFRHADPELRKIIEDDRLLCHPAVIGELALGSLRNRGSVIAFLAAQREVAVATHDEVMVMIDRHNIFSM
GIGYTDAHLLASVLLDRRAALWTRDKRLQGAAGKAGVSLYTPVDRRS

Download         Length: 384 bp

>T199059 NZ_CP097170:c690754-690290 [Escherichia coli]
ATGGATTTTCCACAAAGGGTTAATGGTTGGGCGCTATATGCTCATCCCTGTTTTCAGGAAACCTACGACGCTTTAGTTGC
CGAAGTCGAGACATTAAAGGGAAAAGATCCTGAAAATTATCAGAGAAAAGCCGCCACAAAGTTATTGGCGGTAGTCCATA
AAGTGATTGAGGAGCATATCACGGTCAATCCATCATCACCGGCATTCCGTCATGGCAAGTCGTTAGGCTCTGGGAAAAAT
AAAGACTGGTCACGGGTAAAATTTGGTGCTGGTCGTTATCGTCTCTTCTTTCGTTATAGTGAAAAAGAGAAAGTCATCAT
TCTGGGATGGATGAACGATGAAAACACTCTGCGCACCTACGGTAAAAAAACAGATGCCTATACCGTATTCAGCAAAATGT
TAAAAAGAGGACATCCTCCTGCCGACTGGGAAACCCTCACCCGAGAGACAGAAGAAACCCATTGA

Antitoxin


Download         Length: 67 a.a.        Molecular weight: 7063.27 Da        Isoelectric Point: 11.2292

>AT199059 WP_210632655.1 NZ_CP072867:c289073-288873 [Rhizobium sp. NLR16a]
MRSTINLDDALMQKAKALTGTKETAALVRQALETLVRVESGKRLIALGGTMPEAEAAPRRRSAVAK

Download         Length: 201 bp

>AT199059 NZ_CP097170:c691089-690754 [Escherichia coli]
ATGCCCGCTAATGCTCGCTCTCACGCTGTACTGACCACTGAATCAAAGGTCACGATACGCGGACAAACAACTATCCCCGC
GCCAGTGCGTGAGGCCTTAAAACTGAAGCCAGGCCTGGACAGCATTCATTACGAAATTCTGCCTGGTGGGCAAGTATTTA
TGTGCCGACTGGGAGATGAACAGGAGGATCATACTATGAATGCATTTTTGCGTTTTCTGGATGCAGATATCCAGAACAAC
CCGCAAAAAACTCGTCCATTCAACATTCAACAAGGAAAGAAACTTGTCGCTGGCATGGACGTCAACATTGATGATGAGAT
TGGCGACGACGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
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Antitoxin

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Source
ID
Structure
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References