199057

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pasABC/RelE-HTH
Location 3059523..3060000 Replicon chromosome
Accession NZ_CP072865
Organism Rhizobium sp. NLR16a

Toxin (Protein)


Gene name pasB Uniprot ID -
Locus tag J7U39_RS14935 Protein ID WP_210628889.1
Coordinates 3059523..3059792 (-) Length 90 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID -
Locus tag J7U39_RS14940 Protein ID WP_210631686.1
Coordinates 3059776..3060000 (-) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J7U39_RS14925 (J7U39_14925) 3055032..3058493 - 3462 WP_210628887.1 chromosome segregation SMC family protein -
J7U39_RS14930 (J7U39_14930) 3058596..3059372 - 777 WP_210628888.1 DsbA family protein -
J7U39_RS14935 (J7U39_14935) 3059523..3059792 - 270 WP_210628889.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
J7U39_RS14940 (J7U39_14940) 3059776..3060000 - 225 WP_210631686.1 DUF6290 family protein Antitoxin
J7U39_RS14945 (J7U39_14945) 3060230..3060727 - 498 WP_210628890.1 DUF721 domain-containing protein -
J7U39_RS14950 (J7U39_14950) 3060824..3061927 + 1104 WP_210628891.1 A/G-specific adenine glycosylase -
J7U39_RS14955 (J7U39_14955) 3061930..3062544 + 615 WP_210628892.1 HAD family phosphatase -
J7U39_RS14960 (J7U39_14960) 3062550..3062915 + 366 WP_210628893.1 nuclear transport factor 2 family protein -
J7U39_RS14965 (J7U39_14965) 3063095..3064225 - 1131 WP_210628894.1 site-specific DNA-methyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-88)

Antitoxin

Relaxosome protein TraY

(4-49)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10459.98 Da        Isoelectric Point: 10.0275

>T199057 WP_210628889.1 NZ_CP072865:c3059792-3059523 [Rhizobium sp. NLR16a]
MAWRIEFDRAAERELEKLGHEAARRILRFLNDRVAKLDDPRSIGEALKGSELGDFWKYRIGDYRVIASIDDGTVRILIVR
IGNRRDVYR

Download         Length: 270 bp

>T199057 NZ_CP097170:279279-279386 [Escherichia coli]
ATGACGCTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGCATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8587.78 Da        Isoelectric Point: 4.8894

>AT199057 WP_210631686.1 NZ_CP072865:c3060000-3059776 [Rhizobium sp. NLR16a]
MLALRLPPEIEARLDELARRTGRSKSFYARQAILEHLDDLEDVYLAEKRLEELRRGESDTVPLAELMARHGLEN

Download         Length: 225 bp

>AT199057 NZ_CP097170:c279230-279167 [Escherichia coli]
GTCTAGAGTCAAGATTAGCCCCCGTGGTGTTGTCAGGTGCATAACTGCAACGTGCGGGGGTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References