Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | vapBC/VapC-VapB |
| Location | 2270072..2270666 | Replicon | chromosome |
| Accession | NZ_CP072865 | ||
| Organism | Rhizobium sp. NLR16a | ||
Toxin (Protein)
| Gene name | vapC | Uniprot ID | - |
| Locus tag | J7U39_RS11180 | Protein ID | WP_210628261.1 |
| Coordinates | 2270277..2270666 (+) | Length | 130 a.a. |
Antitoxin (Protein)
| Gene name | vapB | Uniprot ID | - |
| Locus tag | J7U39_RS11175 | Protein ID | WP_210631647.1 |
| Coordinates | 2270072..2270293 (+) | Length | 74 a.a. |
Genomic Context
Location: 2267061..2269928 (2868 bp)
Type: Others
Protein ID: WP_210628260.1
Type: Others
Protein ID: WP_210628260.1
Location: 2270072..2270293 (222 bp)
Type: Antitoxin
Protein ID: WP_210631647.1
Type: Antitoxin
Protein ID: WP_210631647.1
Location: 2270277..2270666 (390 bp)
Type: Toxin
Protein ID: WP_210628261.1
Type: Toxin
Protein ID: WP_210628261.1
Location: 2272516..2273472 (957 bp)
Type: Others
Protein ID: WP_064801874.1
Type: Others
Protein ID: WP_064801874.1
Location: 2273469..2274758 (1290 bp)
Type: Others
Protein ID: WP_210628263.1
Type: Others
Protein ID: WP_210628263.1
Location: 2274801..2275421 (621 bp)
Type: Others
Protein ID: WP_210628264.1
Type: Others
Protein ID: WP_210628264.1
Location: 2265179..2266438 (1260 bp)
Type: Others
Protein ID: WP_210628259.1
Type: Others
Protein ID: WP_210628259.1
Location: 2270679..2272337 (1659 bp)
Type: Others
Protein ID: WP_210628262.1
Type: Others
Protein ID: WP_210628262.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| J7U39_RS11165 (J7U39_11165) | 2265179..2266438 | - | 1260 | WP_210628259.1 | N-acetylmuramoyl-L-alanine amidase | - |
| J7U39_RS11170 (J7U39_11170) | 2267061..2269928 | + | 2868 | WP_210628260.1 | ribonuclease E/G | - |
| J7U39_RS11175 (J7U39_11175) | 2270072..2270293 | + | 222 | WP_210631647.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin |
| J7U39_RS11180 (J7U39_11180) | 2270277..2270666 | + | 390 | WP_210628261.1 | PIN domain nuclease | Toxin |
| J7U39_RS11185 (J7U39_11185) | 2270679..2272337 | - | 1659 | WP_210628262.1 | acyl-CoA dehydrogenase family protein | - |
| J7U39_RS11190 (J7U39_11190) | 2272516..2273472 | + | 957 | WP_064801874.1 | aspartate carbamoyltransferase catalytic subunit | - |
| J7U39_RS11195 (J7U39_11195) | 2273469..2274758 | + | 1290 | WP_210628263.1 | dihydroorotase | - |
| J7U39_RS11200 (J7U39_11200) | 2274801..2275421 | + | 621 | WP_210628264.1 | glycerol-3-phosphate 1-O-acyltransferase PlsY | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 130 a.a. Molecular weight: 14675.95 Da Isoelectric Point: 6.3306
>T199056 WP_210628261.1 NZ_CP072865:2270277-2270666 [Rhizobium sp. NLR16a]
VIVVDSSVWIAHLRGMENAARRRLQNIEDPLEILVGDLILMEVLQGARNDRHATTIEANLRQFTIRPMLDDSLAVRAARN
YRLLRERGITVRKIIDVIIGTFCIQEGHSLLHDDSDFDPMAEHLGLRIA
VIVVDSSVWIAHLRGMENAARRRLQNIEDPLEILVGDLILMEVLQGARNDRHATTIEANLRQFTIRPMLDDSLAVRAARN
YRLLRERGITVRKIIDVIIGTFCIQEGHSLLHDDSDFDPMAEHLGLRIA
Download Length: 390 bp
>T199056 NZ_CP097170:278796-278903 [Escherichia coli]
ATGACGCTCGCAGAACTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGCATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA
ATGACGCTCGCAGAACTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGCATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA
Antitoxin
Download Length: 74 a.a. Molecular weight: 8163.22 Da Isoelectric Point: 10.4368
>AT199056 WP_210631647.1 NZ_CP072865:2270072-2270293 [Rhizobium sp. NLR16a]
MRTNIDIDDALLAAAMTATGLATKKATIEQALRSLVDRHRRKNAIANLSGIGWEGDLEGMRRDRPDETSDRRR
MRTNIDIDDALLAAAMTATGLATKKATIEQALRSLVDRHRRKNAIANLSGIGWEGDLEGMRRDRPDETSDRRR
Download Length: 222 bp
>AT199056 NZ_CP097170:c278747-278684 [Escherichia coli]
GTCTAGGTTCAAGATTAGCCCCCGTGATGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTT
GTCTAGGTTCAAGATTAGCCCCCGTGATGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTT