Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3579971..3580634 Replicon chromosome
Accession NZ_CP072856
Organism Lonsdalea populi strain N-5-1

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag J8X70_RS15880 Protein ID WP_085688707.1
Coordinates 3579971..3580387 (-) Length 139 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag J8X70_RS15885 Protein ID WP_085688773.1
Coordinates 3580368..3580634 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J8X70_RS15860 3575607..3576506 - 900 WP_085688715.1 site-specific tyrosine recombinase XerD -
J8X70_RS15865 3576759..3578087 + 1329 WP_085688776.1 MFS transporter -
J8X70_RS15870 3578246..3578779 + 534 WP_085688712.1 flavodoxin FldB -
J8X70_RS15875 3578841..3579794 - 954 WP_085688709.1 23S rRNA (adenine(1618)-N(6))-methyltransferase RlmF -
J8X70_RS15880 3579971..3580387 - 417 WP_085688707.1 protein YgfX Toxin
J8X70_RS15885 3580368..3580634 - 267 WP_085688773.1 FAD assembly factor SdhE Antitoxin
J8X70_RS15890 3580866..3581846 + 981 WP_085688705.1 tRNA-modifying protein YgfZ -
J8X70_RS15895 3581871..3582518 - 648 WP_085688703.1 hemolysin III family protein -
J8X70_RS15900 3582751..3583353 + 603 WP_085688770.1 HD domain-containing protein -
J8X70_RS15905 3583414..3584736 - 1323 WP_085688700.1 MFS transporter -
J8X70_RS15910 3584736..3585386 - 651 WP_085688697.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-133)

Antitoxin

Flavinator of succinate dehydrogenase

(8-79)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 16113.02 Da        Isoelectric Point: 11.7965

>T199024 WP_085688707.1 NZ_CP072856:c3580387-3579971 [Lonsdalea populi]
VAQWQCDLKVSWRMQLFSLLVHGIMVLLILLAPWPSGYAPLWLGLVSLVMFGFIRSQRNIKSRHGAISLHGERRLRWQQR
EWRIVKRPWMLKSGILLSLRAADGAAQEQRLWLSSDSMGRDEWRHLRQLLLQKDSCAG

Download         Length: 417 bp

>T199024 NZ_CP097107:c4126574-4126290 [Citrobacter freundii]
ATGACTTATGAACTGGAATTCGACCCGAGAGCCTTAAAAGAGTGGCATAAACTGGGTGATACGGTGAAGGCTCAGTTTAA
GAAGAAGTTGGCCGACGTGTTGTTGAACCCCAGAATTGACTCTGCCCGTTTAAACGGTCTTCCAGATTGCTATAAAATTA
AGCTTAAATCGTCCGGCTATCGTCTGGTGTACCAGGTTCGGGATGAGGTTGTGACCGTGTTTGTTGTCGCGGTCGGCAAG
CGAGAGCATTCGGCCGTTTATCTCGATGCAAACAAACGGCTTTAG

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10476.90 Da        Isoelectric Point: 6.0666

>AT199024 WP_085688773.1 NZ_CP072856:c3580634-3580368 [Lonsdalea populi]
MDINDKSRIHWACRRGMRELDISIMPFFEHDYDTLNDSDKNAFVRLLQCDDPDLFNWLMNHGEPSDQELKRMVSLIQTRN
KHRGPVAM

Download         Length: 267 bp

>AT199024 NZ_CP097107:c4126806-4126564 [Citrobacter freundii]
ATGGCCACGCTGAACGTCCGTCTGGATGACAAACTCAAAAATGAGGCTTATGCCGTGCTGGAAAAACTGAACATTACTCC
AACGGAAGCTGTGCGATTACTGTTTCAGTACGTCGCGGAAACGGGGCGCATGCCAGTGAAAACCGTCACCGTTAGCGACA
GCGAAGATACACTGATTCAGACAGTCCGGGAGAGGCTGGCCAGCCCGCAAAAAGGAATCAAGGTTAGTCTGGATGACTTA
TGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References