Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/Doc-RelB
Location 521722..522347 Replicon chromosome
Accession NZ_CP072856
Organism Lonsdalea populi strain N-5-1

Toxin (Protein)


Gene name doc Uniprot ID -
Locus tag J8X70_RS02455 Protein ID WP_085686901.1
Coordinates 521722..522129 (-) Length 136 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID -
Locus tag J8X70_RS02460 Protein ID WP_085686903.1
Coordinates 522126..522347 (-) Length 74 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J8X70_RS02445 517237..518511 + 1275 WP_085686897.1 HlyD family secretion protein -
J8X70_RS02450 518504..520615 + 2112 WP_085686899.1 peptidase domain-containing ABC transporter -
J8X70_RS17210 521183..521314 + 132 WP_254900111.1 hypothetical protein -
J8X70_RS02455 521722..522129 - 408 WP_085686901.1 type II toxin-antitoxin system death-on-curing family toxin Toxin
J8X70_RS02460 522126..522347 - 222 WP_085686903.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
J8X70_RS02465 522674..523537 - 864 WP_085686905.1 YicC/YloC family endoribonuclease -
J8X70_RS02470 523797..524705 - 909 WP_085686907.1 LysR family transcriptional regulator -
J8X70_RS02475 524855..525931 - 1077 WP_085686909.1 dipeptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Fido domain

(3-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-52)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 15239.30 Da        Isoelectric Point: 5.1499

>T199019 WP_085686901.1 NZ_CP072856:c522129-521722 [Lonsdalea populi]
MIWISAQEVIAFHDRILQRLPGVAGITDPGRAEALIYRVQNRAHYEGTTDIFELAATYWVAIARGHIFNDGNKRTAFFVT
MTFLYRNGVKIRDNDNALENLTVEAATGEKTVIQLAQSLRDLMDNFNPTDLIPVD

Download         Length: 408 bp

>T199019 NZ_CP097107:c1272955-1272695 [Citrobacter freundii]
ATGAAAGTCAGGATATCCCCGCAGGCAAAAAGCGATCTTCAATACTGGGCCGAGACTGACCCAAAGACGCATAACAAAGT
AATGGAGTTAATCAAATCGGCTAAGGAAAGCCCCTTCAAGGGGATAGGGAAACCGGAGGCGCTAAAGCACCGTAAGCCCC
TCTGGTCACGTCGCATCACAAAAGAACATCGCCTGGTGTACTACGTTGAGCAAGGCGATCTGTACATTGTCGCGTGTCGT
TATCACTACACCACGATCTAG

Antitoxin


Download         Length: 74 a.a.        Molecular weight: 8153.97 Da        Isoelectric Point: 5.0631

>AT199019 WP_085686903.1 NZ_CP072856:c522347-522126 [Lonsdalea populi]
MRTYTSTQARANISEVLDAATHGEAVEITRRDGSSAVVISKTEFEAYQNAKLDAEFEEIMQRHGHTVEALTNR

Download         Length: 222 bp

>AT199019 NZ_CP097107:c1273200-1272955 [Citrobacter freundii]
ATGCAACACGTAAACTATACCGATGCTCGACAGCATTTAGCTGACCTGATGCAGCAGGCTAATGATGATCGTGCGCCAAT
CCTGGTTACTCGTAAGGGTGCTAAAAGCGTGGTAATGATCGACGCGGAAGAGTTCGCATCGATTCAGGAAACGTTACATC
TGTTCAGTAATCCGGCGAACGCCGCACACATTGAAGCCAGCCTTGCATCACTCGAACGCGGCGATTATGAGGAACTGGAC
ATTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References