Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 999531..1000093 Replicon chromosome
Accession NZ_CP072844
Organism Psychrosphaera aestuarii strain PSC101

Toxin (Protein)


Gene name ccdB Uniprot ID -
Locus tag J9318_RS04605 Protein ID WP_210561704.1
Coordinates 999776..1000093 (+) Length 106 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID -
Locus tag J9318_RS04600 Protein ID WP_210561702.1
Coordinates 999531..999776 (+) Length 82 a.a.

Genomic Context

J9318_RS04600J9318_RS04605J9318_RS04585J9318_RS04590J9318_RS04595J9318_RS04610J9318_RS04615J9318_RS04620J9318_RS04625J9318_RS04630J9318_RS04635
Location: 999531..999776 (246 bp)
Type: Antitoxin
Protein ID: WP_210561702.1
Location: 999776..1000093 (318 bp)
Type: Toxin
Protein ID: WP_210561704.1
Location: 996327..997082 (756 bp)
Type: Others
Protein ID: WP_210561688.1
Location: 997469..998446 (978 bp)
Type: Others
Protein ID: WP_210561690.1
Location: 998484..999350 (867 bp)
Type: Others
Protein ID: WP_210561700.1
Location: 1000181..1000570 (390 bp)
Type: Others
Protein ID: WP_210561711.1
Location: 1000671..1001459 (789 bp)
Type: Others
Protein ID: WP_210561713.1
Location: 1001611..1002501 (891 bp)
Type: Others
Protein ID: WP_210561715.1
Location: 1002656..1003033 (378 bp)
Type: Others
Protein ID: WP_210561717.1
Location: 1003163..1003900 (738 bp)
Type: Others
Protein ID: WP_210561719.1
Location: 1004067..1004399 (333 bp)
Type: Others
Protein ID: WP_210561721.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
J9318_RS04585996327..997082-756WP_210561688.1cytochrome b/b6 domain-containing protein-
J9318_RS04590997469..998446-978WP_210561690.1alpha/beta fold hydrolase-
J9318_RS04595998484..999350-867WP_210561700.1alpha/beta fold hydrolase-
J9318_RS04600999531..999776+246WP_210561702.1type II toxin-antitoxin system CcdA family antitoxinAntitoxin
J9318_RS04605999776..1000093+318WP_210561704.1CcdB family proteinToxin
J9318_RS046101000181..1000570-390WP_210561711.1hypothetical protein-
J9318_RS046151000671..1001459-789WP_210561713.1trypsin-like serine protease-
J9318_RS046201001611..1002501-891WP_210561715.1putative phage abortive infection protein-
J9318_RS046251002656..1003033-378WP_210561717.1hypothetical protein-
J9318_RS046301003163..1003900-738WP_210561719.1hypothetical protein-
J9318_RS046351004067..1004399-333WP_210561721.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin CcdB

(3-104)

Antitoxin

Post-segregation antitoxin CcdA

(11-81)


Sequences

Toxin        


Download         Length: 106 a.a.        Molecular weight: 11810.64 Da        Isoelectric Point: 4.5836

>T198971 WP_210561704.1 NZ_CP072844:999776-1000093 [Psychrosphaera aestuarii]
MPQFSLYKNKDKSTSRAYPFFVDVQSDLLNSLDTRIVIPLTSLELLEGSAPTHLCPIIHLEEGDFVILTQQTTSVPTKML
KEEVTDLRAFRNEIIGALDFLITGI

Download         Length: 318 bp

>T198971 NZ_CP097077:113022-113504 [Klebsiella pneumoniae]
ATGGGAATGAGAGCGCCTGAATCCCTGACGGCTGAACATAACATCGCTGAGTTCTGCTGCCAGGAGCCTGCCCTTAATGA
GTGGTTAAAGAAGAAGGCTCTCAGAAACCACAGTACCGGCATTTCCCGTGTCTATGTCGTCTGCGCAGAAAACACTAACC
GGGTCATCGGTTATTATTGTTTATCTTCGGGTAGCGTCCACCGTAACAAAGTGCCTGGGGCCTATAGACGCAACGCGCCT
GATGTCATTCCAGTCATTGTTTTGGGACGGCTTGCCATCGACCAGGCCTGGGCCGGGAATGGGCTTGGTGCCGCACTTCT
TAAGGATGCTATATACCGTACGCAAAACATAGCCTTTCAGGTCGGGGTGAGAGCACTGGCCGTGCATGCGCTGAATGAAG
AAGTTAAATGTTTTTACACCCGTTTTGGCTTTGAGCCTTCCATAGTCAACACGCTGACATTGTTATTCCCGATAAAAGTC
TGA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9223.34 Da        Isoelectric Point: 6.4611

>AT198971 WP_210561702.1 NZ_CP072844:999531-999776 [Psychrosphaera aestuarii]
MRNVHSTQPTKKATNLSLNSELLAEAKRLNINLSATMEKALEREVSAKLRDEWIQQNADAVESCNKLTEEHGLFSDSYRT
F

Download         Length: 246 bp

>AT198971 NZ_CP097077:112753-113031 [Klebsiella pneumoniae]
ATGAAACCAGACGTTCGTGAAGCTCCGATTAATATCCGGGCCAAAACATCACAGCGTGACCTGATCGACATGGCCGCAAG
CCTGGTCTCAAAATCACGGACTGATTTTATGCTTGAGGTTGCCTGCAGGGAGGCACAGGACATTCTGCTTGATCAACGCC
TGTTCCTCCTCAATGACAATCAGTTTGAGGCGTTTATTGAAGAGCTTGACGCCCCAATAACGCCGGAGCGCCAGGCGCGA
ATCGATAACCTGATGAACCGCAAATCACCATGGGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References