Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2323665..2323810 Replicon chromosome
Accession NZ_CP072825
Organism Klebsiella pneumoniae strain IRQBAS103c

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2323701..2323803 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2323665..2323810 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J9262_RS11295 2318795..2320855 + 2061 WP_130947155.1 oligopeptidase B -
J9262_RS11300 2320859..2321518 - 660 WP_002911407.1 exodeoxyribonuclease X -
J9262_RS11305 2321597..2321827 - 231 WP_002911406.1 DNA polymerase III subunit theta -
J9262_RS11310 2321940..2322314 + 375 WP_004151448.1 CopC domain-containing protein YobA -
J9262_RS11315 2322318..2323187 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
J9262_RS11320 2323204..2323542 + 339 WP_002911404.1 YebY family protein -
- 2323665..2323810 - 146 - - Antitoxin
- 2323701..2323803 + 103 - - Toxin
J9262_RS11325 2324178..2324321 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
J9262_RS11330 2324426..2325394 - 969 WP_206552288.1 VirK/YbjX family protein -
J9262_RS11335 2325551..2326204 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
J9262_RS11340 2326201..2326392 - 192 WP_002911395.1 YebW family protein -
J9262_RS11345 2326490..2326729 - 240 WP_002911393.1 YebV family protein -
J9262_RS11350 2326845..2328278 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T198925 NZ_CP072825:2323701-2323803 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT198925 NZ_CP072825:c2323810-2323665 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References