Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 301963..302234 Replicon chromosome
Accession NZ_CP072802
Organism Escherichia coli strain PK5074

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 302093..302196 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 301963..302234 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J8617_RS01455 298518..299180 - 663 WP_000944258.1 exodeoxyribonuclease X -
J8617_RS01460 299204..299860 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
J8617_RS01465 299962..300192 - 231 WP_000916763.1 DNA polymerase III subunit theta -
J8617_RS01470 300331..300705 + 375 WP_000168747.1 CopC domain-containing protein YobA -
J8617_RS01475 300709..301581 + 873 WP_000879295.1 copper homeostasis membrane protein CopD -
J8617_RS01480 301594..301935 + 342 WP_000976472.1 YebY family protein -
- 301963..302234 - 272 - - Antitoxin
- 302093..302196 + 104 - - Toxin
J8617_RS01485 302331..302987 + 657 WP_000812732.1 protein-serine/threonine phosphatase -
J8617_RS01490 302988..303179 - 192 WP_001338167.1 YebW family protein -
J8617_RS01495 303284..303520 - 237 WP_001338166.1 YebV family protein -
J8617_RS01500 303638..305077 - 1440 WP_001351758.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T198893 NZ_CP072802:302093-302196 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT198893 NZ_CP072802:c302234-301963 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References