Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relBE/YoeB-YefM
Location 3716693..3717195 Replicon chromosome
Accession NZ_CP072801
Organism Thiothrix litoralis strain AS

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag J9253_RS17975 Protein ID WP_028489823.1
Coordinates 3716693..3716947 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag J9253_RS17980 Protein ID WP_028489824.1
Coordinates 3716944..3717195 (-) Length 84 a.a.

Genomic Context


J9253_RS17970J9253_RS17985J9253_RS17960J9253_RS17965J9253_RS17975J9253_RS17980J9253_RS17990J9253_RS17995J9253_RS18000
Location: 3715526..3716659 (1134 bp)
Type: Others
Protein ID: WP_210222237.1
Location: 3717355..3719130 (1776 bp)
Type: Others
Protein ID: WP_210222238.1
Location: 3713489..3714673 (1185 bp)
Type: Others
Protein ID: WP_210222236.1
Location: 3714700..3715389 (690 bp)
Type: Others
Protein ID: WP_228291424.1
Location: 3716693..3716947 (255 bp)
Type: Toxin
Protein ID: WP_028489823.1
Location: 3716944..3717195 (252 bp)
Type: Antitoxin
Protein ID: WP_028489824.1
Location: 3719199..3719503 (305 bp)
Type: Others
Protein ID: Protein_3568
Location: 3719476..3721113 (1638 bp)
Type: Others
Protein ID: WP_228291596.1
Location: 3721319..3722020 (702 bp)
Type: Others
Protein ID: WP_210222240.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
J9253_RS17960 (J9253_17960)3713489..3714673-1185WP_210222236.1hypothetical protein-
J9253_RS17965 (J9253_17965)3714700..3715389-690WP_228291424.1ABC transporter ATP-binding protein-
J9253_RS17970 (J9253_17970)3715526..3716659+1134WP_210222237.1hypothetical protein-
J9253_RS17975 (J9253_17975)3716693..3716947-255WP_028489823.1Txe/YoeB family addiction module toxinToxin
J9253_RS17980 (J9253_17980)3716944..3717195-252WP_028489824.1type II toxin-antitoxin system prevent-host-death family antitoxinAntitoxin
J9253_RS17985 (J9253_17985)3717355..3719130+1776WP_210222238.1N-acetylglutaminylglutamine amidotransferase-
J9253_RS17990 (J9253_17990)3719199..3719503-305Protein_3568transposase-
J9253_RS17995 (J9253_17995)3719476..3721113-1638WP_228291596.1polysaccharide deacetylase family protein-
J9253_RS18000 (J9253_18000)3721319..3722020-702WP_210222240.1hypothetical protein-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(1-84)

Antitoxin

(1-73)


Sequences


Toxin        


Download         Length: 85 a.a.        Molecular weight: 10155.74 Da        Isoelectric Point: 9.3464

>T198892 WP_028489823.1 NZ_CP072801:c3716947-3716693 [Thiothrix litoralis]
MRIVFSSKAWEDYLYWQQADKKILKRINELIKAISREPFEGIGKPEPLRHGLSGYWSRRINDEHRLVYKVEGEDLLIAMC
RYHY

Download         Length: 255 bp

>T198892 NZ_CP097046:2699847-2699990 [Enterococcus faecalis]
ATGAATGTAAGTACTAAAACCTATGAAAGGAGAGGCCTTTTGTCTATCGCAGAAGCTTTAGCTCTGATGATTAGTTTCGG
TTCTTTTATCGCAACGTTAATCTTCGGAATCCTAGAGGCTGTTAAAGAAGACAATAAAAAATAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9337.64 Da        Isoelectric Point: 4.6386

>AT198892 WP_028489824.1 NZ_CP072801:c3717195-3716944 [Thiothrix litoralis]
MNAISYTAVRAELAKTMDRVCEDHEPIIITRNREQAVVMISLEDYKAMEETAYLLRSPANASRLLESIAELGRGNGQARE
LLE

Download         Length: 252 bp

>AT198892 NZ_CP097046:c2700184-2699922 [Enterococcus faecalis]
AAATAAAAATGCCCGAGCCTCTTATTTTTCTAAGGCTCGGGCATTTTTATTGATGGTCTTTTGAGGGTCGTTGTGCTACA
ATGGTAATGAAAAGAGAGGTATGCGCCAACATACCTCTCTAGTGTAGAGCCGTTTCAGACGGTAGCGATTTTTAGTGATT
TATAAAAAATAACCGTGCTCGCTAAAGTTGACGGTTATTTTTTATTGTCTTCTTTAACAGCCTCTAGGATTCCGAAGATT
AACGTTGCGATAAAAGAACCGAA

Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
No matching records found


Antitoxin

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Source
ID
Structure
No matching records found

References