Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | vapBC/VapC-VagC |
| Location | 1698407..1699032 | Replicon | chromosome |
| Accession | NZ_CP072801 | ||
| Organism | Thiothrix litoralis strain AS | ||
Toxin (Protein)
| Gene name | vapC | Uniprot ID | - |
| Locus tag | J9253_RS08225 | Protein ID | WP_210224123.1 |
| Coordinates | 1698407..1698805 (-) | Length | 133 a.a. |
Antitoxin (Protein)
| Gene name | vapB | Uniprot ID | - |
| Locus tag | J9253_RS08230 | Protein ID | WP_093069820.1 |
| Coordinates | 1698805..1699032 (-) | Length | 76 a.a. |
Genomic Context
Location: 1693945..1694664 (720 bp)
Type: Others
Protein ID: WP_210224120.1
Type: Others
Protein ID: WP_210224120.1
Location: 1694668..1695645 (978 bp)
Type: Others
Protein ID: WP_210224121.1
Type: Others
Protein ID: WP_210224121.1
Location: 1696204..1697677 (1474 bp)
Type: Others
Protein ID: Protein_1645
Type: Others
Protein ID: Protein_1645
Location: 1698023..1698334 (312 bp)
Type: Others
Protein ID: WP_210224122.1
Type: Others
Protein ID: WP_210224122.1
Location: 1698407..1698805 (399 bp)
Type: Toxin
Protein ID: WP_210224123.1
Type: Toxin
Protein ID: WP_210224123.1
Location: 1698805..1699032 (228 bp)
Type: Antitoxin
Protein ID: WP_093069820.1
Type: Antitoxin
Protein ID: WP_093069820.1
Location: 1699157..1700797 (1641 bp)
Type: Others
Protein ID: WP_210224124.1
Type: Others
Protein ID: WP_210224124.1
Location: 1700815..1701105 (291 bp)
Type: Others
Protein ID: WP_210224125.1
Type: Others
Protein ID: WP_210224125.1
Location: 1701204..1701677 (474 bp)
Type: Others
Protein ID: WP_210224126.1
Type: Others
Protein ID: WP_210224126.1
Location: 1701756..1703750 (1995 bp)
Type: Others
Protein ID: WP_210224127.1
Type: Others
Protein ID: WP_210224127.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| J9253_RS08205 (J9253_08205) | 1693945..1694664 | + | 720 | WP_210224120.1 | ATP-binding protein | - |
| J9253_RS08210 (J9253_08210) | 1694668..1695645 | + | 978 | WP_210224121.1 | 2OG-Fe(II) oxygenase family protein | - |
| J9253_RS08215 (J9253_08215) | 1696204..1697677 | + | 1474 | Protein_1645 | ISNCY family transposase | - |
| J9253_RS08220 (J9253_08220) | 1698023..1698334 | + | 312 | WP_210224122.1 | hypothetical protein | - |
| J9253_RS08225 (J9253_08225) | 1698407..1698805 | - | 399 | WP_210224123.1 | type II toxin-antitoxin system VapC family toxin | Toxin |
| J9253_RS08230 (J9253_08230) | 1698805..1699032 | - | 228 | WP_093069820.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin |
| J9253_RS08235 (J9253_08235) | 1699157..1700797 | - | 1641 | WP_210224124.1 | chaperonin GroEL | - |
| J9253_RS08240 (J9253_08240) | 1700815..1701105 | - | 291 | WP_210224125.1 | co-chaperone GroES | - |
| J9253_RS08245 (J9253_08245) | 1701204..1701677 | - | 474 | WP_210224126.1 | FxsA family protein | - |
| J9253_RS08250 (J9253_08250) | 1701756..1703750 | - | 1995 | WP_210224127.1 | EAL domain-containing protein | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 133 a.a. Molecular weight: 14839.33 Da Isoelectric Point: 9.6916
>T198887 WP_210224123.1 NZ_CP072801:c1698805-1698407 [Thiothrix litoralis]
MKYLLDTNICIYLIKEKPPAVLVRFTALKPAQVFISAVTVFELYYGVENSQAHKRNLAALEKFLRPMTILDFTPEDAKQA
ARIRADLKRKGTPIGAYDLQIAATALANGLTVVTNNTDEFQRVVGLRLENWV
MKYLLDTNICIYLIKEKPPAVLVRFTALKPAQVFISAVTVFELYYGVENSQAHKRNLAALEKFLRPMTILDFTPEDAKQA
ARIRADLKRKGTPIGAYDLQIAATALANGLTVVTNNTDEFQRVVGLRLENWV
Download Length: 399 bp
>T198887 NZ_CP097046:c2608396-2608253 [Enterococcus faecalis]
ATGAGCGTACTTCCAAAATTTACAGAAAGGAGAGGCCTGTTGTCAGCATATGAAACAATTCAGACGATCCTAGGGTTTGG
TATGTTTACCATTGCTTTGATTGCGCTGATTGTGAAATTGCTTAAAAATGACAATAAAAAATAA
ATGAGCGTACTTCCAAAATTTACAGAAAGGAGAGGCCTGTTGTCAGCATATGAAACAATTCAGACGATCCTAGGGTTTGG
TATGTTTACCATTGCTTTGATTGCGCTGATTGTGAAATTGCTTAAAAATGACAATAAAAAATAA
Antitoxin
Download Length: 76 a.a. Molecular weight: 8764.85 Da Isoelectric Point: 4.5557
>AT198887 WP_093069820.1 NZ_CP072801:c1699032-1698805 [Thiothrix litoralis]
MQTAKIFQNGRSQAIRLPKAFRLSGTEVKISRDGNRIILEPLEQSWDDWLLAIEQFSDDFMAEGRDQPAVQEREW
MQTAKIFQNGRSQAIRLPKAFRLSGTEVKISRDGNRIILEPLEQSWDDWLLAIEQFSDDFMAEGRDQPAVQEREW
Download Length: 228 bp
>AT198887 NZ_CP097046:2608497-2608695 [Enterococcus faecalis]
TTTTTAGGGAAATGTGCTATAATGAAAATGAAAAGAGAGATATGCTTCAACATACCTCTCTAGTGTAGAGCCGTTTGAGA
CGGTGACCGATTATATTATTTAAAAATAACCGTACTGGTCAAAGTAGACGGTTATTTTTTATTGTCATTTTTAAGCAATT
TCACAATCAGTGCAATCAAAGCAATGGTAAACATACCAA
TTTTTAGGGAAATGTGCTATAATGAAAATGAAAAGAGAGATATGCTTCAACATACCTCTCTAGTGTAGAGCCGTTTGAGA
CGGTGACCGATTATATTATTTAAAAATAACCGTACTGGTCAAAGTAGACGGTTATTTTTTATTGTCATTTTTAAGCAATT
TCACAATCAGTGCAATCAAAGCAATGGTAAACATACCAA