Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 3308558..3309197 Replicon chromosome
Accession NZ_CP072793
Organism Thiothrix unzii strain A1

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag J9260_RS16515 Protein ID WP_210218807.1
Coordinates 3308781..3309197 (+) Length 139 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag J9260_RS16510 Protein ID WP_210218806.1
Coordinates 3308558..3308794 (+) Length 79 a.a.

Genomic Context

J9260_RS16510J9260_RS16515J9260_RS16520J9260_RS16525J9260_RS16530J9260_RS16535J9260_RS16540
Location: 3308558..3308794 (237 bp)
Type: Antitoxin
Protein ID: WP_210218806.1
Location: 3308781..3309197 (417 bp)
Type: Toxin
Protein ID: WP_210218807.1
Location: 3309443..3310645 (1203 bp)
Type: Others
Protein ID: WP_210218808.1
Location: 3310658..3311608 (951 bp)
Type: Others
Protein ID: WP_210218809.1
Location: 3311586..3311792 (207 bp)
Type: Others
Protein ID: WP_210218810.1
Location: 3311813..3312544 (732 bp)
Type: Others
Protein ID: WP_210218811.1
Location: 3312676..3313833 (1158 bp)
Type: Others
Protein ID: WP_210218812.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
J9260_RS16510 (J9260_16505)3308558..3308794+237WP_210218806.1DNA-binding proteinAntitoxin
J9260_RS16515 (J9260_16510)3308781..3309197+417WP_210218807.1type II toxin-antitoxin system VapC family toxinToxin
J9260_RS16520 (J9260_16515)3309443..3310645+1203WP_210218808.1RtcB family protein-
J9260_RS16525 (J9260_16520)3310658..3311608+951WP_210218809.1hypothetical protein-
J9260_RS16530 (J9260_16525)3311586..3311792+207WP_210218810.1hypothetical protein-
J9260_RS16535 (J9260_16530)3311813..3312544+732WP_210218811.1MipA/OmpV family protein-
J9260_RS16540 (J9260_16535)3312676..3313833+1158WP_210218812.1ChaN family lipoprotein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-124)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 15702.81 Da        Isoelectric Point: 6.3315

>T198870 WP_210218807.1 NZ_CP072793:3308781-3309197 [Thiothrix unzii]
MYLLDTNVISEIRKGQRANSGVQAFFQRVINNGDRLWLSAVTIGELRRGIELIRRRNDATQALQLEHWLEQILSEYQDHI
IGVDADTAQLWGRLRVPHHEHELDKLIAASALLYDLTVVTRNVDDFAGTGAKLLNPFS

Download         Length: 417 bp

>T198870 NZ_CP097038:2718213-2718356 [Enterococcus faecalis]
ATGAATGTAAGTACTAAAATCTATGAAAGGAGAGGCCTTTTGTCTATCGCAGAAGCTTTAGCTCTGATGATTAGTTTCGG
TTCTTTTATCGCAACGTTAATCTTCGGAATCCTAGAGGCTGTAAAAGAAAACAATAAAAAATAA

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 8768.26 Da        Isoelectric Point: 10.1783

>AT198870 WP_210218806.1 NZ_CP072793:3308558-3308794 [Thiothrix unzii]
MSNLIVRKLEPEIIEALKQRAARNGRSAEMEHRAILREVLLVLKKRSLAEILAAMPNVGTDADFERIQGKQQVADVFA

Download         Length: 237 bp

>AT198870 NZ_CP097038:c2718102-2718039 [Enterococcus faecalis]
TTGTGCTATAATAGCAATGAAAAGAGAGATATGCTGTAACATACCTCTCTGATGTAGAGCCGTT

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References