Detailed information of TA system TA198870

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/VapC-StbC
• Location: 3308558..3309197
• Replicon: chromosome
• Accession: NZ_CP072793
• Organism: Thiothrix unzii strain A1

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: J9260_RS16515
• Protein ID: WP_210218807.1
• Coordinates: 3308781..3309197 (+)
• Length: 139 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: J9260_RS16510
• Protein ID: WP_210218806.1
• Coordinates: 3308558..3308794 (+)
• Length: 79 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
J9260_RS16510 (J9260_16505)	3308558..3308794	+	237	WP_210218806.1	DNA-binding protein	Antitoxin
J9260_RS16515 (J9260_16510)	3308781..3309197	+	417	WP_210218807.1	type II toxin-antitoxin system VapC family toxin	Toxin
J9260_RS16520 (J9260_16515)	3309443..3310645	+	1203	WP_210218808.1	RtcB family protein	-
J9260_RS16525 (J9260_16520)	3310658..3311608	+	951	WP_210218809.1	hypothetical protein	-
J9260_RS16530 (J9260_16525)	3311586..3311792	+	207	WP_210218810.1	hypothetical protein	-
J9260_RS16535 (J9260_16530)	3311813..3312544	+	732	WP_210218811.1	MipA/OmpV family protein	-
J9260_RS16540 (J9260_16535)	3312676..3313833	+	1158	WP_210218812.1	ChaN family lipoprotein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (2-124)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 139 a.a.
• Molecular weight: 15702.81 Da
• Isoelectric Point: 6.3315

>T198870 WP_210218807.1 NZ_CP072793:3308781-3309197 [Thiothrix unzii]
MYLLDTNVISEIRKGQRANSGVQAFFQRVINNGDRLWLSAVTIGELRRGIELIRRRNDATQALQLEHWLEQILSEYQDHI
IGVDADTAQLWGRLRVPHHEHELDKLIAASALLYDLTVVTRNVDDFAGTGAKLLNPFS

Nucleotide

• Length: 417 bp

>T198870 NZ_CP097038:2718213-2718356 [Enterococcus faecalis]
ATGAATGTAAGTACTAAAATCTATGAAAGGAGAGGCCTTTTGTCTATCGCAGAAGCTTTAGCTCTGATGATTAGTTTCGG
TTCTTTTATCGCAACGTTAATCTTCGGAATCCTAGAGGCTGTAAAAGAAAACAATAAAAAATAA

Antitoxin

Protein

• Length: 79 a.a.
• Molecular weight: 8768.26 Da
• Isoelectric Point: 10.1783

>AT198870 WP_210218806.1 NZ_CP072793:3308558-3308794 [Thiothrix unzii]
MSNLIVRKLEPEIIEALKQRAARNGRSAEMEHRAILREVLLVLKKRSLAEILAAMPNVGTDADFERIQGKQQVADVFA

Nucleotide

• Length: 237 bp

>AT198870 NZ_CP097038:c2718102-2718039 [Enterococcus faecalis]
TTGTGCTATAATAGCAATGAAAAGAGAGATATGCTGTAACATACCTCTCTGATGTAGAGCCGTT