Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 1004038..1004663 Replicon chromosome
Accession NZ_CP072793
Organism Thiothrix unzii strain A1

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag J9260_RS05195 Protein ID WP_210219975.1
Coordinates 1004265..1004663 (+) Length 133 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag J9260_RS05190 Protein ID WP_210219974.1
Coordinates 1004038..1004265 (+) Length 76 a.a.

Genomic Context

J9260_RS05170J9260_RS05175J9260_RS05180J9260_RS05185J9260_RS05190J9260_RS05195J9260_RS05210J9260_RS05215J9260_RS05200J9260_RS05205
Location: 999290..1001260 (1971 bp)
Type: Others
Protein ID: WP_246499642.1
Location: 1001351..1001821 (471 bp)
Type: Others
Protein ID: WP_210219972.1
Location: 1001920..1002210 (291 bp)
Type: Others
Protein ID: WP_093069816.1
Location: 1002230..1003867 (1638 bp)
Type: Others
Protein ID: WP_210219973.1
Location: 1004038..1004265 (228 bp)
Type: Antitoxin
Protein ID: WP_210219974.1
Location: 1004265..1004663 (399 bp)
Type: Toxin
Protein ID: WP_210219975.1
Location: 1006381..1007079 (699 bp)
Type: Others
Protein ID: WP_210219978.1
Location: 1007248..1008849 (1602 bp)
Type: Others
Protein ID: WP_210219979.1
Location: 1004791..1005069 (279 bp)
Type: Others
Protein ID: WP_210219976.1
Location: 1005332..1006267 (936 bp)
Type: Others
Protein ID: WP_210219977.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
J9260_RS05170 (J9260_05165)999290..1001260+1971WP_246499642.1EAL domain-containing protein-
J9260_RS05175 (J9260_05170)1001351..1001821+471WP_210219972.1FxsA family protein-
J9260_RS05180 (J9260_05175)1001920..1002210+291WP_093069816.1co-chaperone GroES-
J9260_RS05185 (J9260_05180)1002230..1003867+1638WP_210219973.1chaperonin GroEL-
J9260_RS05190 (J9260_05185)1004038..1004265+228WP_210219974.1type II toxin-antitoxin system VapB family antitoxinAntitoxin
J9260_RS05195 (J9260_05190)1004265..1004663+399WP_210219975.1type II toxin-antitoxin system VapC family toxinToxin
J9260_RS05200 (J9260_05195)1004791..1005069-279WP_210219976.1hypothetical protein-
J9260_RS05205 (J9260_05200)1005332..1006267-936WP_210219977.12OG-Fe(II) oxygenase family protein-
J9260_RS05210 (J9260_05205)1006381..1007079+699WP_210219978.1Crp/Fnr family transcriptional regulator-
J9260_RS05215 (J9260_05210)1007248..1008849+1602WP_210219979.1cytochrome ubiquinol oxidase subunit I-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-123)

Antitoxin

SpoVT-AbrB domain

(7-49)


Sequences

Toxin        


Download         Length: 133 a.a.        Molecular weight: 14911.40 Da        Isoelectric Point: 9.3779

>T198863 WP_210219975.1 NZ_CP072793:1004265-1004663 [Thiothrix unzii]
MKYLLDTNICIYLIKEKPPEVLLRFTALKPAQVFISAVTVFELYYGVENSQAHKRNLAALEKFLRPMTILDFTPEDAKQA
ARIRADLKRKGTPIGAYDLQIAATALANGLTVVTNNTDEFQRVVGLRLENWV

Download         Length: 399 bp

>T198863 NZ_CP097035:c35598-34735 [Enterococcus faecalis]
ATGGCGAATATTACTGACTTCACCGAAAAGCAATTTGAAGATCGTTTAGAAAAGAATGTTGAACGACTAACTAAAAATAG
ACTAGCGGTTGAATCGCCAACCGCTTTTTTACTTGGTGGGCAACCAGGGTCAGGGAAAACCAGTTTGCGATCAGCAATTT
TTGAAGAAACACAAGGGAATGTTATTGTCATTGATAATGATACCTTTAAACAACAGCACCCAAATTTTGACGAATTAGTG
AAACTCTATGAAAAAGACGTAGTAAAACACGTTACCCCTTATTCGAATCGCATGACAGAAGCACTTATTAGCCGTTTAAG
CGATCAAGGCTATAATTTAGTGATTGAAGGAACAGGACGAACAACAGACGTTCCCATTCAAACAGCCACAATGCTTCAAT
CTAAAGGTTATGAAACAAAAATGTATGTCATGGCAGTACCTAAAATCAACTCATATTTAGGAACAATTGAACGGTATGAA
ACTATGTATGCAGATGATCCAATGACAGCCAGGGCAACACCAAAACAAGCGCATGATATTGTTGTCAAAAACTTACCGAC
CAATTTAGAAACCCTTCATAAAACGGGCTTATTTAGCGATATAAGGCTTTACAATAGAGAAGGAGTGAAACTCTATTCAA
GCTTAGAAACGCCTTCCATTAGTCCGAAAGAGACCTTAGAAAGAGAATTAAATCGTAAAGTATCAGGGAAAGAAATTCAA
CCGACTTTGGAGAGAATAGAGCAAAAAATGGTTCAAAATCAACACCAAGAAACCCCTGAATTTAAAGCAATTCAACAAAA
AATGGAAAGCTTGCAGCCACCTACACCACCAATACCCAAAACACCTAAACTTCCAGGGATTTAA

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8818.99 Da        Isoelectric Point: 6.3084

>AT198863 WP_210219974.1 NZ_CP072793:1004038-1004265 [Thiothrix unzii]
MQTAKIFQNGRSQAIRLPKAFRLSGTEVRISREGNRIILEPLKQSWDDWLLAIEQFSDDFMAQGREQPAVQEREW

Download         Length: 228 bp

>AT198863 NZ_CP097035:c35872-35600 [Enterococcus faecalis]
ATGGCAGTTACGTATGAAAAAACATTTGAAATTGAAATCATTAATGAGTTATCGGCAAGTGTTTATAATCGGGTATTAAA
TTATGTTTTGAATCATGAACTAGATACTAAAAATACTCGTTTACTAGAAGTGAATCTTTTAAATCAATTAGAAGTGGCAC
AAGAAGTTGATTTATTTCAACAACCATTTGAAGAATTACAAGCTATTCATGAGTATTGGCGGTCAATGAATCAATATTCA
AAACAAATTTTGAATAAAGAGAAAGTGGCTTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References