Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-YefM
Location 350072..350577 Replicon chromosome
Accession NZ_CP072793
Organism Thiothrix unzii strain A1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag J9260_RS02040 Protein ID WP_210219401.1
Coordinates 350320..350577 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag J9260_RS02035 Protein ID WP_210219400.1
Coordinates 350072..350329 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J9260_RS02010 (J9260_02005) 345478..347253 - 1776 WP_210219395.1 N-acetylglutaminylglutamine amidotransferase -
J9260_RS02015 (J9260_02010) 347337..347690 - 354 WP_210219396.1 hypothetical protein -
J9260_RS02020 (J9260_02015) 348208..348606 - 399 WP_210219397.1 hypothetical protein -
J9260_RS02025 (J9260_02020) 348636..348971 - 336 WP_210219398.1 hypothetical protein -
J9260_RS02030 (J9260_02025) 348968..349894 - 927 WP_210219399.1 ATP-binding protein -
J9260_RS02035 (J9260_02030) 350072..350329 + 258 WP_210219400.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
J9260_RS02040 (J9260_02035) 350320..350577 + 258 WP_210219401.1 Txe/YoeB family addiction module toxin Toxin
J9260_RS02045 (J9260_02040) 350590..351615 - 1026 WP_210219402.1 hypothetical protein -
J9260_RS02050 (J9260_02045) 351814..352998 + 1185 WP_210219403.1 PDC sensor domain-containing protein -
J9260_RS02055 (J9260_02050) 353092..353679 + 588 WP_210219404.1 Fe-Mn family superoxide dismutase -
J9260_RS02060 (J9260_02055) 353830..354996 + 1167 WP_246499589.1 aspartate aminotransferase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10170.72 Da        Isoelectric Point: 9.4094

>T198862 WP_210219401.1 NZ_CP072793:350320-350577 [Thiothrix unzii]
MRIIFSSKAWEDYGHWQQADKKILKRINDLIKAISREPFEGIGKPEPLRHGLSGYWSRRINDEHRLVYKVEGEDLLIAMC
RYHYP

Download         Length: 258 bp

>T198862 NZ_CP097034:2680536-2680679 [Enterococcus faecalis]
ATGAATGTAAGTACTAAAATCTATGAAAGGAGAGGCCTTTTGTCTATCGCAGAAGCTTTAGCTCTGATGATTAGTTTCGG
TTCTTTTATCGCAACGTTAATCTTCGGAATCCTAGAGGCTGTTAAAGAAGACAATAAAAAATAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9641.96 Da        Isoelectric Point: 4.4002

>AT198862 WP_210219400.1 NZ_CP072793:350072-350329 [Thiothrix unzii]
MNAISYTAVRADLAKTMDRVCEDHEPVIITRNRDQAVVMISLEDYKAMEETAYLLRSPANASRLLESIAELERGQGQVRE
LIECE

Download         Length: 258 bp

>AT198862 NZ_CP097034:c2680873-2680611 [Enterococcus faecalis]
AAATAAAAATGCCCGAGCCTCTTATTTTTCTAAGGCTCGGGCATTTTTATTGATGGTCTTTTGAGGGTCGTTGTGCTATA
ATGGTAATGAAAAGAGAGGTATGCGCCAACATACCTCTCTAGTGTAGAGCCGTTTCAGACGGTAGCGATTTTTAGTGATT
TATAAAAAATAACCGTGCTCGCTAAAGTTGACGGTTATTTTTTATTGTCTTCTTTAACAGCCTCTAGGATTCCGAAGATT
AACGTTGCGATAAAAGAACCGAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References