Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/YoeB-YefM |
| Location | 350072..350577 | Replicon | chromosome |
| Accession | NZ_CP072793 | ||
| Organism | Thiothrix unzii strain A1 | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | - |
| Locus tag | J9260_RS02040 | Protein ID | WP_210219401.1 |
| Coordinates | 350320..350577 (+) | Length | 86 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | - |
| Locus tag | J9260_RS02035 | Protein ID | WP_210219400.1 |
| Coordinates | 350072..350329 (+) | Length | 86 a.a. |
Genomic Context
Location: 350072..350329 (258 bp)
Type: Antitoxin
Protein ID: WP_210219400.1
Type: Antitoxin
Protein ID: WP_210219400.1
Location: 350320..350577 (258 bp)
Type: Toxin
Protein ID: WP_210219401.1
Type: Toxin
Protein ID: WP_210219401.1
Location: 351814..352998 (1185 bp)
Type: Others
Protein ID: WP_210219403.1
Type: Others
Protein ID: WP_210219403.1
Location: 353092..353679 (588 bp)
Type: Others
Protein ID: WP_210219404.1
Type: Others
Protein ID: WP_210219404.1
Location: 353830..354996 (1167 bp)
Type: Others
Protein ID: WP_246499589.1
Type: Others
Protein ID: WP_246499589.1
Location: 345478..347253 (1776 bp)
Type: Others
Protein ID: WP_210219395.1
Type: Others
Protein ID: WP_210219395.1
Location: 347337..347690 (354 bp)
Type: Others
Protein ID: WP_210219396.1
Type: Others
Protein ID: WP_210219396.1
Location: 348208..348606 (399 bp)
Type: Others
Protein ID: WP_210219397.1
Type: Others
Protein ID: WP_210219397.1
Location: 348636..348971 (336 bp)
Type: Others
Protein ID: WP_210219398.1
Type: Others
Protein ID: WP_210219398.1
Location: 348968..349894 (927 bp)
Type: Others
Protein ID: WP_210219399.1
Type: Others
Protein ID: WP_210219399.1
Location: 350590..351615 (1026 bp)
Type: Others
Protein ID: WP_210219402.1
Type: Others
Protein ID: WP_210219402.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| J9260_RS02010 (J9260_02005) | 345478..347253 | - | 1776 | WP_210219395.1 | N-acetylglutaminylglutamine amidotransferase | - |
| J9260_RS02015 (J9260_02010) | 347337..347690 | - | 354 | WP_210219396.1 | hypothetical protein | - |
| J9260_RS02020 (J9260_02015) | 348208..348606 | - | 399 | WP_210219397.1 | hypothetical protein | - |
| J9260_RS02025 (J9260_02020) | 348636..348971 | - | 336 | WP_210219398.1 | hypothetical protein | - |
| J9260_RS02030 (J9260_02025) | 348968..349894 | - | 927 | WP_210219399.1 | ATP-binding protein | - |
| J9260_RS02035 (J9260_02030) | 350072..350329 | + | 258 | WP_210219400.1 | type II toxin-antitoxin system prevent-host-death family antitoxin | Antitoxin |
| J9260_RS02040 (J9260_02035) | 350320..350577 | + | 258 | WP_210219401.1 | Txe/YoeB family addiction module toxin | Toxin |
| J9260_RS02045 (J9260_02040) | 350590..351615 | - | 1026 | WP_210219402.1 | hypothetical protein | - |
| J9260_RS02050 (J9260_02045) | 351814..352998 | + | 1185 | WP_210219403.1 | PDC sensor domain-containing protein | - |
| J9260_RS02055 (J9260_02050) | 353092..353679 | + | 588 | WP_210219404.1 | Fe-Mn family superoxide dismutase | - |
| J9260_RS02060 (J9260_02055) | 353830..354996 | + | 1167 | WP_246499589.1 | aspartate aminotransferase family protein | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 86 a.a. Molecular weight: 10170.72 Da Isoelectric Point: 9.4094
>T198862 WP_210219401.1 NZ_CP072793:350320-350577 [Thiothrix unzii]
MRIIFSSKAWEDYGHWQQADKKILKRINDLIKAISREPFEGIGKPEPLRHGLSGYWSRRINDEHRLVYKVEGEDLLIAMC
RYHYP
MRIIFSSKAWEDYGHWQQADKKILKRINDLIKAISREPFEGIGKPEPLRHGLSGYWSRRINDEHRLVYKVEGEDLLIAMC
RYHYP
Download Length: 258 bp
>T198862 NZ_CP097034:2680536-2680679 [Enterococcus faecalis]
ATGAATGTAAGTACTAAAATCTATGAAAGGAGAGGCCTTTTGTCTATCGCAGAAGCTTTAGCTCTGATGATTAGTTTCGG
TTCTTTTATCGCAACGTTAATCTTCGGAATCCTAGAGGCTGTTAAAGAAGACAATAAAAAATAA
ATGAATGTAAGTACTAAAATCTATGAAAGGAGAGGCCTTTTGTCTATCGCAGAAGCTTTAGCTCTGATGATTAGTTTCGG
TTCTTTTATCGCAACGTTAATCTTCGGAATCCTAGAGGCTGTTAAAGAAGACAATAAAAAATAA
Antitoxin
Download Length: 86 a.a. Molecular weight: 9641.96 Da Isoelectric Point: 4.4002
>AT198862 WP_210219400.1 NZ_CP072793:350072-350329 [Thiothrix unzii]
MNAISYTAVRADLAKTMDRVCEDHEPVIITRNRDQAVVMISLEDYKAMEETAYLLRSPANASRLLESIAELERGQGQVRE
LIECE
MNAISYTAVRADLAKTMDRVCEDHEPVIITRNRDQAVVMISLEDYKAMEETAYLLRSPANASRLLESIAELERGQGQVRE
LIECE
Download Length: 258 bp
>AT198862 NZ_CP097034:c2680873-2680611 [Enterococcus faecalis]
AAATAAAAATGCCCGAGCCTCTTATTTTTCTAAGGCTCGGGCATTTTTATTGATGGTCTTTTGAGGGTCGTTGTGCTATA
ATGGTAATGAAAAGAGAGGTATGCGCCAACATACCTCTCTAGTGTAGAGCCGTTTCAGACGGTAGCGATTTTTAGTGATT
TATAAAAAATAACCGTGCTCGCTAAAGTTGACGGTTATTTTTTATTGTCTTCTTTAACAGCCTCTAGGATTCCGAAGATT
AACGTTGCGATAAAAGAACCGAA
AAATAAAAATGCCCGAGCCTCTTATTTTTCTAAGGCTCGGGCATTTTTATTGATGGTCTTTTGAGGGTCGTTGTGCTATA
ATGGTAATGAAAAGAGAGGTATGCGCCAACATACCTCTCTAGTGTAGAGCCGTTTCAGACGGTAGCGATTTTTAGTGATT
TATAAAAAATAACCGTGCTCGCTAAAGTTGACGGTTATTTTTTATTGTCTTCTTTAACAGCCTCTAGGATTCCGAAGATT
AACGTTGCGATAAAAGAACCGAA