Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2257566..2257797 Replicon chromosome
Accession NZ_CP072688
Organism Escherichia coli strain P4

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2257694..2257796 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2257566..2257797 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J8I92_RS10745 2254120..2254782 - 663 WP_000944256.1 exodeoxyribonuclease X -
J8I92_RS10750 2254805..2255461 - 657 WP_000011664.1 carbon-nitrogen hydrolase family protein YobB -
J8I92_RS10755 2255563..2255793 - 231 WP_000916763.1 DNA polymerase III subunit theta -
J8I92_RS10760 2255932..2256306 + 375 WP_000168747.1 CopC domain-containing protein YobA -
J8I92_RS10765 2256310..2257182 + 873 WP_000879311.1 copper homeostasis membrane protein CopD -
J8I92_RS10770 2257195..2257536 + 342 WP_000977376.1 YebY family protein -
- 2257566..2257797 - 232 - - Antitoxin
- 2257694..2257796 + 103 - - Toxin
J8I92_RS10775 2257927..2259003 - 1077 WP_001189088.1 phage integrase Arm DNA-binding domain-containing protein -
J8I92_RS10780 2258969..2259250 - 282 WP_023234152.1 excisionase -
J8I92_RS10785 2259357..2259545 - 189 WP_001356607.1 DUF1187 family protein -
- 2259361..2259539 + 179 NuclAT_0 - -
- 2259361..2259539 + 179 NuclAT_0 - -
- 2259361..2259539 + 179 NuclAT_0 - -
- 2259361..2259539 + 179 NuclAT_0 - -
J8I92_RS10790 2259538..2259732 - 195 WP_042047457.1 type I toxin-antitoxin system endodeoxyribonuclease toxin RalR -
J8I92_RS10795 2259789..2260598 - 810 WP_000166317.1 recombination protein RecT -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2250155..2314625 64470


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T198290 NZ_CP072688:2257694-2257796 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 232 bp

>AT198290 NZ_CP072688:c2257797-2257566 [Escherichia coli]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References