Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2257315..2257546 Replicon chromosome
Accession NZ_CP072686
Organism Escherichia coli strain FP4

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2257443..2257545 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2257315..2257546 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J8I94_RS10735 2253869..2254531 - 663 WP_000944256.1 exodeoxyribonuclease X -
J8I94_RS10740 2254554..2255210 - 657 WP_000011664.1 carbon-nitrogen hydrolase family protein YobB -
J8I94_RS10745 2255312..2255542 - 231 WP_000916763.1 DNA polymerase III subunit theta -
J8I94_RS10750 2255681..2256055 + 375 WP_000168747.1 CopC domain-containing protein YobA -
J8I94_RS10755 2256059..2256931 + 873 WP_000879311.1 copper homeostasis membrane protein CopD -
J8I94_RS10760 2256944..2257285 + 342 WP_000977376.1 YebY family protein -
- 2257315..2257546 - 232 - - Antitoxin
- 2257443..2257545 + 103 - - Toxin
J8I94_RS10765 2257676..2258752 - 1077 WP_001189088.1 phage integrase Arm DNA-binding domain-containing protein -
J8I94_RS10770 2258718..2258999 - 282 WP_023234152.1 excisionase -
J8I94_RS10775 2259106..2259294 - 189 WP_001356607.1 DUF1187 family protein -
- 2259110..2259288 + 179 NuclAT_0 - -
- 2259110..2259288 + 179 NuclAT_0 - -
- 2259110..2259288 + 179 NuclAT_0 - -
- 2259110..2259288 + 179 NuclAT_0 - -
J8I94_RS10780 2259287..2259481 - 195 WP_042047457.1 type I toxin-antitoxin system endodeoxyribonuclease toxin RalR -
J8I94_RS10785 2259538..2260345 - 808 Protein_2112 recombination protein RecT -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2251812..2314372 62560


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T198240 NZ_CP072686:2257443-2257545 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 232 bp

>AT198240 NZ_CP072686:c2257546-2257315 [Escherichia coli]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References