Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 1404622..1405181 Replicon chromosome
Accession NZ_CP072680
Organism Vibrio sp. SCSIO 43186

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag J8Z27_RS06690 Protein ID WP_252036435.1
Coordinates 1404622..1404900 (-) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag J8Z27_RS06695 Protein ID WP_252036436.1
Coordinates 1404897..1405181 (-) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J8Z27_RS06645 (J8Z27_06590) 1399924..1400319 + 396 WP_252036428.1 cupin domain-containing protein -
J8Z27_RS06650 (J8Z27_06595) 1400460..1400870 + 411 WP_252036429.1 hypothetical protein -
J8Z27_RS06655 (J8Z27_06600) 1401009..1401470 + 462 WP_252036430.1 DUF1851 domain-containing protein -
J8Z27_RS06660 1401607..1401792 + 186 WP_252036664.1 hypothetical protein -
J8Z27_RS06665 (J8Z27_06605) 1401759..1402076 + 318 WP_252036431.1 GNAT family N-acetyltransferase -
J8Z27_RS06670 (J8Z27_06610) 1402223..1402654 + 432 WP_252036432.1 hypothetical protein -
J8Z27_RS23365 1402692..1402823 + 132 WP_255906341.1 hypothetical protein -
J8Z27_RS06675 (J8Z27_06615) 1402962..1403435 + 474 WP_252036433.1 GrpB family protein -
J8Z27_RS06680 (J8Z27_06620) 1403583..1403999 + 417 WP_252036434.1 GFA family protein -
J8Z27_RS06685 (J8Z27_06625) 1404488..1404592 + 105 WP_252036618.1 DUF3265 domain-containing protein -
J8Z27_RS06690 (J8Z27_06630) 1404622..1404900 - 279 WP_252036435.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
J8Z27_RS06695 (J8Z27_06635) 1404897..1405181 - 285 WP_252036436.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
J8Z27_RS06700 (J8Z27_06640) 1405860..1406345 - 486 WP_252036437.1 hypothetical protein -
J8Z27_RS06705 (J8Z27_06645) 1406496..1406588 + 93 WP_193837464.1 DUF3265 domain-containing protein -
J8Z27_RS06710 (J8Z27_06650) 1407471..1407620 + 150 WP_252036438.1 hypothetical protein -
J8Z27_RS06715 (J8Z27_06655) 1408129..1408569 + 441 WP_252036439.1 hypothetical protein -
J8Z27_RS06720 (J8Z27_06660) 1409441..1409860 + 420 WP_252036440.1 lysozyme inhibitor LprI family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1303177..1430025 126848
- inside Integron - - 1302170..1428889 126719


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-89)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(5-44)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10934.60 Da        Isoelectric Point: 4.4755

>T198230 WP_252036435.1 NZ_CP072680:c1404900-1404622 [Vibrio sp. SCSIO 43186]
MIFWEEESLNDREKIFEFLYDFNPEAAEKTDEVIEAKVENLLEQPHMGVQRDGIRGRLLIIPEISMIVSYWIEGDIIRIM
RVLHQKQKFPAS

Download         Length: 279 bp

>T198230 NZ_CP096843:2233262-2233660 [Mycobacterium tuberculosis variant bovis]
ATGATCGTCGACACCTCGGTCTGGATCGCATATCTCTCCACGTCAGAGTCGTTGGCCAGTCGCTGGCTAGCCGATCGCAT
TGCCGCTGACTCGACGGTGATCGTGCCCGAGGTGGTGATGATGGAGCTGCTGATCGGTAAGACCGATGAGGACACCGCCG
CACTGCGCCGACGGCTCCTGCAGCGATTCGCTATCGAACCGCTGGCCCCGGTCCGCGACGCGGAAGATGCCGCCGCCATT
CACCGGCGCTGTCGTCGCGGCGGCGACACCGTACGCAGCCTGATCGATTGCCAGGTGGCCGCGATGGCGTTGCGGATCGG
GGTCGCCGTGGCGCATCGTGATCGCGACTACGAGGCGATCCGCACACATTGCGGACTACGCACCGAGCCGTTGTTCTGA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10938.31 Da        Isoelectric Point: 9.1865

>AT198230 WP_252036436.1 NZ_CP072680:c1405181-1404897 [Vibrio sp. SCSIO 43186]
MDTRIQFRVDEETKRLAQQMAESQGRTLSDACRELTEQLADQQRKTLSHDAWLTEQVNLAFEKFDLGKANFVDHESAKSR
MAERKAKIRNRGKV

Download         Length: 285 bp

>AT198230 NZ_CP096843:2233034-2233261 [Mycobacterium tuberculosis variant bovis]
GTGTCACGGACCAACATCGAGATCGACGACGAACTCGTGGCCGCCGCACAGCGGATGTACCGACTCGATTCCAAGCGAAG
TGCCGTCGACCTCGCGCTGCGCCGGCTCGTGGGTGAACCGTTGGGCCGCGATGAGGCTTTGGCGCTGCAGGGCAGCGGTT
TCGACTTCAGCGACGATGAGATCGAATCGTTCTCGGATACGGACCGCAAGCTCGCCGACGAGTCGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References