Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | parDE/ParE-YefM |
| Location | 1344263..1344808 | Replicon | chromosome |
| Accession | NZ_CP072680 | ||
| Organism | Vibrio sp. SCSIO 43186 | ||
Toxin (Protein)
| Gene name | parE | Uniprot ID | A0A151KUE6 |
| Locus tag | J8Z27_RS06225 | Protein ID | WP_038939651.1 |
| Coordinates | 1344263..1344559 (-) | Length | 99 a.a. |
Antitoxin (Protein)
| Gene name | parD | Uniprot ID | - |
| Locus tag | J8Z27_RS06230 | Protein ID | WP_239866745.1 |
| Coordinates | 1344566..1344808 (-) | Length | 81 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| J8Z27_RS06180 (J8Z27_06155) | 1339374..1339724 | + | 351 | WP_252036372.1 | hypothetical protein | - |
| J8Z27_RS06185 (J8Z27_06160) | 1340339..1340648 | + | 310 | Protein_1187 | DUF4144 family protein | - |
| J8Z27_RS06190 (J8Z27_06165) | 1340791..1341288 | + | 498 | WP_170966842.1 | hypothetical protein | - |
| J8Z27_RS06195 (J8Z27_06170) | 1341426..1341797 | + | 372 | WP_252036373.1 | RidA family protein | - |
| J8Z27_RS06200 (J8Z27_06175) | 1341949..1342338 | + | 390 | WP_252036374.1 | hypothetical protein | - |
| J8Z27_RS06205 (J8Z27_06180) | 1342482..1342937 | - | 456 | WP_252036375.1 | hypothetical protein | - |
| J8Z27_RS06210 | 1343020..1343202 | + | 183 | WP_252036376.1 | hypothetical protein | - |
| J8Z27_RS06215 (J8Z27_06185) | 1343544..1343684 | + | 141 | WP_252036377.1 | hypothetical protein | - |
| J8Z27_RS06220 (J8Z27_06190) | 1343744..1344091 | + | 348 | WP_239866754.1 | hypothetical protein | - |
| J8Z27_RS06225 (J8Z27_06195) | 1344263..1344559 | - | 297 | WP_038939651.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| J8Z27_RS06230 (J8Z27_06200) | 1344566..1344808 | - | 243 | WP_239866745.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
| J8Z27_RS06235 (J8Z27_06205) | 1345062..1345799 | + | 738 | WP_239876928.1 | SDR family oxidoreductase | - |
| J8Z27_RS06240 | 1345777..1345914 | + | 138 | WP_239876929.1 | DUF3265 domain-containing protein | - |
| J8Z27_RS06245 (J8Z27_06210) | 1347223..1347471 | + | 249 | WP_252036378.1 | hypothetical protein | - |
| J8Z27_RS06250 (J8Z27_06215) | 1347700..1347936 | + | 237 | WP_252036379.1 | hypothetical protein | - |
| J8Z27_RS06255 (J8Z27_06220) | 1348327..1348989 | + | 663 | WP_252036380.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Genomic island | - | - | 1303177..1430025 | 126848 | |
| - | inside | Integron | - | - | 1302170..1428889 | 126719 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 99 a.a. Molecular weight: 11278.93 Da Isoelectric Point: 9.6269
>T198228 WP_038939651.1 NZ_CP072680:c1344559-1344263 [Vibrio sp. SCSIO 43186]
MQKNKYKLSKLAQTHLQKIKNYTVNNFSEMQWRSYKDTLLTGFQMLADNPAVGRSCDEIYPSGFYFPVGKHTAYFTKEDG
FILVVAVLGQSQLPQNHL
MQKNKYKLSKLAQTHLQKIKNYTVNNFSEMQWRSYKDTLLTGFQMLADNPAVGRSCDEIYPSGFYFPVGKHTAYFTKEDG
FILVVAVLGQSQLPQNHL
Download Length: 297 bp
>T198228 NZ_CP096843:c2208288-2207728 [Mycobacterium tuberculosis variant bovis]
GTGAGCGATGCCCTCGATGAAGGGCTCGTCCAGCGTATCGACGCACGCGGAACAATTGAGTGGTCGGAAACGTGCTACCG
GTATACCGGCGCGCACCGTGACGCCTTGTCCGGTGAGGGCGCGCGCAGATTCGGAGGCAGGTGGAATCCGCCGCTGCTCT
TTCCGGCGATCTATCTTGCTGATTCCGCCCAAGCCTGCATGGTTGAGGTGGAACGGGCGGCGCAAGCGGCTTCAACGACC
GCAGAGAAGATGCTCGAGGCGGCCTACCGACTACACACGATCGACGTCACGGACCTGGCCGTCCTCGATCTGACAACCCC
GCAAGCTCGGGAAGCCGTGGGGCTCGAGAACGACGACATCTATGGCGACGACTGGTCAGGGTGCCAGGCGGTCGGACATG
CGGCCTGGTTCTTGCACATGCAAGGTGTCCTCGTGCCGGCGGCGGGCGGTGTCGGCCTCGTTGTCACCGCGTATGAACAG
CGAACTCGGCCGGGCCAACTACAACTGCGACAAAGCGTCGATCTGACGCCTGCTCTTTACCAAGAACTTCGAGCCACGTA
G
GTGAGCGATGCCCTCGATGAAGGGCTCGTCCAGCGTATCGACGCACGCGGAACAATTGAGTGGTCGGAAACGTGCTACCG
GTATACCGGCGCGCACCGTGACGCCTTGTCCGGTGAGGGCGCGCGCAGATTCGGAGGCAGGTGGAATCCGCCGCTGCTCT
TTCCGGCGATCTATCTTGCTGATTCCGCCCAAGCCTGCATGGTTGAGGTGGAACGGGCGGCGCAAGCGGCTTCAACGACC
GCAGAGAAGATGCTCGAGGCGGCCTACCGACTACACACGATCGACGTCACGGACCTGGCCGTCCTCGATCTGACAACCCC
GCAAGCTCGGGAAGCCGTGGGGCTCGAGAACGACGACATCTATGGCGACGACTGGTCAGGGTGCCAGGCGGTCGGACATG
CGGCCTGGTTCTTGCACATGCAAGGTGTCCTCGTGCCGGCGGCGGGCGGTGTCGGCCTCGTTGTCACCGCGTATGAACAG
CGAACTCGGCCGGGCCAACTACAACTGCGACAAAGCGTCGATCTGACGCCTGCTCTTTACCAAGAACTTCGAGCCACGTA
G
Antitoxin
Download Length: 81 a.a. Molecular weight: 9030.23 Da Isoelectric Point: 4.7914
>AT198228 WP_239866745.1 NZ_CP072680:c1344808-1344566 [Vibrio sp. SCSIO 43186]
MHTLTANDAKRNFGELLLSAQREPVKISKNSKDAVVVMSIKDYEELEAMKTDYLRHCFESAKQDLVQGNVVDGEDFLNAL
MHTLTANDAKRNFGELLLSAQREPVKISKNSKDAVVVMSIKDYEELEAMKTDYLRHCFESAKQDLVQGNVVDGEDFLNAL
Download Length: 243 bp
>AT198228 NZ_CP096843:c2208626-2208285 [Mycobacterium tuberculosis variant bovis]
ATGGGAGTAAATGTGCTCGCCTCGACCGTGTCGGGTGCGATCGAGCGCTTGGGATTGACCTACGAGGAAGTCGGTGACAT
CGTCGATGCCTCGCCGCGTTCCGTGGCGCGATGGACCGCAGGTCAGGTGGTTCCCCAACGCCTCAACAAGCAACGACTTA
TCGAGCTGGCCTATGTCGCCGACGCCCTCGCGGAAGTGCTGCCGCGTGACCAGGCGAACGTGTGGATGTTTTCGCCGAAT
CGGTTACTGGAACACCGCAAGCCTGCCGACCTCGTGCGAGACGGCGAGTACCAACGCGTGTTGGCGCTCATCGACGCGAT
GGCGGAGGGAGTGTTCGTGTGA
ATGGGAGTAAATGTGCTCGCCTCGACCGTGTCGGGTGCGATCGAGCGCTTGGGATTGACCTACGAGGAAGTCGGTGACAT
CGTCGATGCCTCGCCGCGTTCCGTGGCGCGATGGACCGCAGGTCAGGTGGTTCCCCAACGCCTCAACAAGCAACGACTTA
TCGAGCTGGCCTATGTCGCCGACGCCCTCGCGGAAGTGCTGCCGCGTGACCAGGCGAACGTGTGGATGTTTTCGCCGAAT
CGGTTACTGGAACACCGCAAGCCTGCCGACCTCGTGCGAGACGGCGAGTACCAACGCGTGTTGGCGCTCATCGACGCGAT
GGCGGAGGGAGTGTTCGTGTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|