Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1829599..1829744 Replicon chromosome
Accession NZ_CP072653
Organism Klebsiella pneumoniae strain KPN234

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1829635..1829737 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1829599..1829744 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J8J76_RS08820 (J8J76_08820) 1824729..1826789 + 2061 WP_069339950.1 oligopeptidase B -
J8J76_RS08825 (J8J76_08825) 1826793..1827452 - 660 WP_002911407.1 exodeoxyribonuclease X -
J8J76_RS08830 (J8J76_08830) 1827531..1827761 - 231 WP_002911406.1 DNA polymerase III subunit theta -
J8J76_RS08835 (J8J76_08835) 1827874..1828248 + 375 WP_004151448.1 CopC domain-containing protein YobA -
J8J76_RS08840 (J8J76_08840) 1828252..1829121 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
J8J76_RS08845 (J8J76_08845) 1829138..1829476 + 339 WP_002911404.1 YebY family protein -
- 1829599..1829744 - 146 - - Antitoxin
- 1829635..1829737 + 103 - - Toxin
J8J76_RS08850 (J8J76_08850) 1830113..1830256 - 144 WP_038431282.1 Ecr family regulatory small membrane protein -
J8J76_RS08855 (J8J76_08855) 1830361..1831329 - 969 WP_004151446.1 VirK/YbjX family protein -
J8J76_RS08860 (J8J76_08860) 1831486..1832139 + 654 WP_023280291.1 protein-serine/threonine phosphatase -
J8J76_RS08865 (J8J76_08865) 1832136..1832327 - 192 WP_002911395.1 YebW family protein -
J8J76_RS08870 (J8J76_08870) 1832425..1832664 - 240 WP_002911393.1 YebV family protein -
J8J76_RS08875 (J8J76_08875) 1832780..1834213 - 1434 WP_069339948.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T198206 NZ_CP072653:1829635-1829737 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT198206 NZ_CP072653:c1829744-1829599 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References