Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | IV | Classification (family/domain) | cptAB/Cpta(toxin) |
Location | 2232116..2232785 | Replicon | chromosome |
Accession | NZ_CP072652 | ||
Organism | Serratia symbiotica strain 24.1 |
Toxin (Protein)
Gene name | cptA | Uniprot ID | - |
Locus tag | GPZ83_RS11540 | Protein ID | WP_040266965.1 |
Coordinates | 2232116..2232538 (-) | Length | 141 a.a. |
Antitoxin (Protein)
Gene name | cptB | Uniprot ID | - |
Locus tag | GPZ83_RS11545 | Protein ID | WP_160744350.1 |
Coordinates | 2232519..2232785 (-) | Length | 89 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
GPZ83_RS11520 (GPZ83_0011515) | 2227844..2229574 | - | 1731 | WP_160744352.1 | single-stranded-DNA-specific exonuclease RecJ | - |
GPZ83_RS11525 (GPZ83_0011520) | 2229581..2230297 | - | 717 | WP_040266963.1 | bifunctional protein-disulfide isomerase/oxidoreductase DsbC | - |
GPZ83_RS11530 (GPZ83_0011525) | 2230310..2231209 | - | 900 | WP_006709292.1 | site-specific tyrosine recombinase XerD | - |
GPZ83_RS11535 (GPZ83_0011530) | 2231452..2231970 | + | 519 | WP_040266964.1 | flavodoxin FldB | - |
GPZ83_RS11540 (GPZ83_0011535) | 2232116..2232538 | - | 423 | WP_040266965.1 | protein YgfX | Toxin |
GPZ83_RS11545 (GPZ83_0011540) | 2232519..2232785 | - | 267 | WP_160744350.1 | FAD assembly factor SdhE | Antitoxin |
GPZ83_RS11550 (GPZ83_0011545) | 2233118..2234104 | + | 987 | WP_006709289.1 | tRNA-modifying protein YgfZ | - |
GPZ83_RS11555 (GPZ83_0011550) | 2234384..2235058 | - | 675 | WP_040266967.1 | hemolysin III family protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 141 a.a. Molecular weight: 16783.77 Da Isoelectric Point: 10.0541
>T198201 WP_040266965.1 NZ_CP072652:c2232538-2232116 [Serratia symbiotica]
VAQWRCDVRISRRTQLFSLLTHGVLVLLILISPWPAGYGPIWLVLLILVVFQGIRSQKRLAAVQGELRLLADWRINWHGR
EWRLVKKPWMPDYGILLTLHPMEGNKYQRLWLVLDNMEREEWRYLRQRLLYPPVSDDEET
VAQWRCDVRISRRTQLFSLLTHGVLVLLILISPWPAGYGPIWLVLLILVVFQGIRSQKRLAAVQGELRLLADWRINWHGR
EWRLVKKPWMPDYGILLTLHPMEGNKYQRLWLVLDNMEREEWRYLRQRLLYPPVSDDEET
Download Length: 423 bp
>T198201 NZ_CP096843:c696291-695899 [Mycobacterium tuberculosis variant bovis]
GTGAACGTACGGCGCGCCCTCGCCGACACATCCGTTTTCATTGGCATCGAGGCGACACGATTCGACCCGGACCGGTTTGC
GGGATACGAATGGGGCGTCTCGGTAGTCACACTCGGCGAGCTGCGGCTCGGGGTGTTGCAAGCCTCCGGCCCCGAGGCCG
CCGCACGTCGGCTCTCCACCTACCAGCTTGCGCAACGGTTCGAACCACTAGGCATCGACGAGGCGGTCTCCGAAGCATGG
GCATTACTGGTGTCCAAGCTGCGCGCCGCCAAACTGCGCGTGCCGATCAACGACAGCTGGATTGCGGCCACAGCCGTGGC
GCACGGCATTGCGATCCTGACCCAAGACAACGACTACGCCGCCATGCCCGACGTCGAGGTCATAACGATCTGA
GTGAACGTACGGCGCGCCCTCGCCGACACATCCGTTTTCATTGGCATCGAGGCGACACGATTCGACCCGGACCGGTTTGC
GGGATACGAATGGGGCGTCTCGGTAGTCACACTCGGCGAGCTGCGGCTCGGGGTGTTGCAAGCCTCCGGCCCCGAGGCCG
CCGCACGTCGGCTCTCCACCTACCAGCTTGCGCAACGGTTCGAACCACTAGGCATCGACGAGGCGGTCTCCGAAGCATGG
GCATTACTGGTGTCCAAGCTGCGCGCCGCCAAACTGCGCGTGCCGATCAACGACAGCTGGATTGCGGCCACAGCCGTGGC
GCACGGCATTGCGATCCTGACCCAAGACAACGACTACGCCGCCATGCCCGACGTCGAGGTCATAACGATCTGA
Antitoxin
Download Length: 89 a.a. Molecular weight: 10429.97 Da Isoelectric Point: 4.8052
>AT198201 WP_160744350.1 NZ_CP072652:c2232785-2232519 [Serratia symbiotica]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDQLNDTDKALFIRLLECDDPDLFNWLMNHGAPEDSELQRMVVLIQSRN
KARGPVAM
MDINNKARIHWACRRGMRELDISIMPFFEYEYDQLNDTDKALFIRLLECDDPDLFNWLMNHGAPEDSELQRMVVLIQSRN
KARGPVAM
Download Length: 267 bp
>AT198201 NZ_CP096843:c696545-696288 [Mycobacterium tuberculosis variant bovis]
ATGTCTGCTACGATACCCGCTCGCGATCTTCGCAACCACACCGCCGAGGTACTGCGGCGAGTTGCCGCCGGCGAGGAAAT
CGAGGTGCTCAAGGACAATCGCCCCGTAGCGCGCATCGTTCCGCTCAAGCGGCGCCGCCAATGGTTGCCAGCTGCCGAGG
TGATCGGCGAACTGGTGCGCTTGGGCCCCGATACCACCAATCTGGGCGAGGAGCTGCGAGAGACGCTGACGCAAACCACG
GACGATGTGCGGTGGTGA
ATGTCTGCTACGATACCCGCTCGCGATCTTCGCAACCACACCGCCGAGGTACTGCGGCGAGTTGCCGCCGGCGAGGAAAT
CGAGGTGCTCAAGGACAATCGCCCCGTAGCGCGCATCGTTCCGCTCAAGCGGCGCCGCCAATGGTTGCCAGCTGCCGAGG
TGATCGGCGAACTGGTGCGCTTGGGCCCCGATACCACCAATCTGGGCGAGGAGCTGCGAGAGACGCTGACGCAAACCACG
GACGATGTGCGGTGGTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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