Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 2232116..2232785 Replicon chromosome
Accession NZ_CP072652
Organism Serratia symbiotica strain 24.1

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag GPZ83_RS11540 Protein ID WP_040266965.1
Coordinates 2232116..2232538 (-) Length 141 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag GPZ83_RS11545 Protein ID WP_160744350.1
Coordinates 2232519..2232785 (-) Length 89 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GPZ83_RS11520 (GPZ83_0011515) 2227844..2229574 - 1731 WP_160744352.1 single-stranded-DNA-specific exonuclease RecJ -
GPZ83_RS11525 (GPZ83_0011520) 2229581..2230297 - 717 WP_040266963.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
GPZ83_RS11530 (GPZ83_0011525) 2230310..2231209 - 900 WP_006709292.1 site-specific tyrosine recombinase XerD -
GPZ83_RS11535 (GPZ83_0011530) 2231452..2231970 + 519 WP_040266964.1 flavodoxin FldB -
GPZ83_RS11540 (GPZ83_0011535) 2232116..2232538 - 423 WP_040266965.1 protein YgfX Toxin
GPZ83_RS11545 (GPZ83_0011540) 2232519..2232785 - 267 WP_160744350.1 FAD assembly factor SdhE Antitoxin
GPZ83_RS11550 (GPZ83_0011545) 2233118..2234104 + 987 WP_006709289.1 tRNA-modifying protein YgfZ -
GPZ83_RS11555 (GPZ83_0011550) 2234384..2235058 - 675 WP_040266967.1 hemolysin III family protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(2-131)

Antitoxin

(7-79)


Sequences


Toxin        


Download         Length: 141 a.a.        Molecular weight: 16783.77 Da        Isoelectric Point: 10.0541

>T198201 WP_040266965.1 NZ_CP072652:c2232538-2232116 [Serratia symbiotica]
VAQWRCDVRISRRTQLFSLLTHGVLVLLILISPWPAGYGPIWLVLLILVVFQGIRSQKRLAAVQGELRLLADWRINWHGR
EWRLVKKPWMPDYGILLTLHPMEGNKYQRLWLVLDNMEREEWRYLRQRLLYPPVSDDEET

Download         Length: 423 bp

>T198201 NZ_CP096843:c696291-695899 [Mycobacterium tuberculosis variant bovis]
GTGAACGTACGGCGCGCCCTCGCCGACACATCCGTTTTCATTGGCATCGAGGCGACACGATTCGACCCGGACCGGTTTGC
GGGATACGAATGGGGCGTCTCGGTAGTCACACTCGGCGAGCTGCGGCTCGGGGTGTTGCAAGCCTCCGGCCCCGAGGCCG
CCGCACGTCGGCTCTCCACCTACCAGCTTGCGCAACGGTTCGAACCACTAGGCATCGACGAGGCGGTCTCCGAAGCATGG
GCATTACTGGTGTCCAAGCTGCGCGCCGCCAAACTGCGCGTGCCGATCAACGACAGCTGGATTGCGGCCACAGCCGTGGC
GCACGGCATTGCGATCCTGACCCAAGACAACGACTACGCCGCCATGCCCGACGTCGAGGTCATAACGATCTGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10429.97 Da        Isoelectric Point: 4.8052

>AT198201 WP_160744350.1 NZ_CP072652:c2232785-2232519 [Serratia symbiotica]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDQLNDTDKALFIRLLECDDPDLFNWLMNHGAPEDSELQRMVVLIQSRN
KARGPVAM

Download         Length: 267 bp

>AT198201 NZ_CP096843:c696545-696288 [Mycobacterium tuberculosis variant bovis]
ATGTCTGCTACGATACCCGCTCGCGATCTTCGCAACCACACCGCCGAGGTACTGCGGCGAGTTGCCGCCGGCGAGGAAAT
CGAGGTGCTCAAGGACAATCGCCCCGTAGCGCGCATCGTTCCGCTCAAGCGGCGCCGCCAATGGTTGCCAGCTGCCGAGG
TGATCGGCGAACTGGTGCGCTTGGGCCCCGATACCACCAATCTGGGCGAGGAGCTGCGAGAGACGCTGACGCAAACCACG
GACGATGTGCGGTGGTGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References