Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | hicAB/HicA-HicB |
| Location | 661872..662305 | Replicon | chromosome |
| Accession | NZ_CP072635 | ||
| Organism | Chloracidobacterium sp. D | ||
Toxin (Protein)
| Gene name | hicA | Uniprot ID | - |
| Locus tag | J8C01_RS13950 | Protein ID | WP_211432825.1 |
| Coordinates | 662081..662305 (+) | Length | 75 a.a. |
Antitoxin (Protein)
| Gene name | hicB | Uniprot ID | - |
| Locus tag | J8C01_RS13945 | Protein ID | WP_211432824.1 |
| Coordinates | 661872..662084 (+) | Length | 71 a.a. |
Genomic Context
Location: 656947..657483 (537 bp)
Type: Others
Protein ID: WP_211432821.1
Type: Others
Protein ID: WP_211432821.1
Location: 657502..657978 (477 bp)
Type: Others
Protein ID: WP_014100927.1
Type: Others
Protein ID: WP_014100927.1
Location: 658247..658525 (279 bp)
Type: Others
Protein ID: WP_014100926.1
Type: Others
Protein ID: WP_014100926.1
Location: 658792..659313 (522 bp)
Type: Others
Protein ID: WP_014100925.1
Type: Others
Protein ID: WP_014100925.1
Location: 659389..661314 (1926 bp)
Type: Others
Protein ID: WP_249355504.1
Type: Others
Protein ID: WP_249355504.1
Location: 661427..661669 (243 bp)
Type: Others
Protein ID: WP_211427109.1
Type: Others
Protein ID: WP_211427109.1
Location: 661656..661820 (165 bp)
Type: Others
Protein ID: Protein_542
Type: Others
Protein ID: Protein_542
Location: 661872..662084 (213 bp)
Type: Antitoxin
Protein ID: WP_211432824.1
Type: Antitoxin
Protein ID: WP_211432824.1
Location: 662081..662305 (225 bp)
Type: Toxin
Protein ID: WP_211432825.1
Type: Toxin
Protein ID: WP_211432825.1
Location: 663957..665030 (1074 bp)
Type: Others
Protein ID: WP_211432826.1
Type: Others
Protein ID: WP_211432826.1
Location: 665253..666083 (831 bp)
Type: Others
Protein ID: WP_211432827.1
Type: Others
Protein ID: WP_211432827.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| J8C01_RS13905 (J8C01_13905) | 656947..657483 | + | 537 | WP_211432821.1 | hypothetical protein | - |
| J8C01_RS13910 (J8C01_13910) | 657502..657978 | + | 477 | WP_014100927.1 | DUF4157 domain-containing protein | - |
| J8C01_RS13920 (J8C01_13920) | 658247..658525 | + | 279 | WP_014100926.1 | acylphosphatase | - |
| J8C01_RS13925 (J8C01_13925) | 658792..659313 | + | 522 | WP_014100925.1 | adenine phosphoribosyltransferase | - |
| J8C01_RS13930 (J8C01_13930) | 659389..661314 | + | 1926 | WP_249355504.1 | CocE/NonD family hydrolase | - |
| J8C01_RS13935 (J8C01_13935) | 661427..661669 | + | 243 | WP_211427109.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | - |
| J8C01_RS13940 (J8C01_13940) | 661656..661820 | + | 165 | Protein_542 | type II toxin-antitoxin system PemK/MazF family toxin | - |
| J8C01_RS13945 (J8C01_13945) | 661872..662084 | + | 213 | WP_211432824.1 | type II toxin-antitoxin system HicB family antitoxin | Antitoxin |
| J8C01_RS13950 (J8C01_13950) | 662081..662305 | + | 225 | WP_211432825.1 | type II toxin-antitoxin system HicA family toxin | Toxin |
| J8C01_RS13955 (J8C01_13955) | 663957..665030 | + | 1074 | WP_211432826.1 | lipopolysaccharide heptosyltransferase II | - |
| J8C01_RS13960 (J8C01_13960) | 665253..666083 | + | 831 | WP_211432827.1 | bifunctional 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 75 a.a. Molecular weight: 8517.96 Da Isoelectric Point: 10.2015
>T198192 WP_211432825.1 NZ_CP072635:662081-662305 [Chloracidobacterium sp. D]
VSDLPKISGRELVKALKKIGYEQDRQRGSHIILRQIDPPHRRVTVPDHKEIAKGTLWTIIREIGLTIDELKDLL
VSDLPKISGRELVKALKKIGYEQDRQRGSHIILRQIDPPHRRVTVPDHKEIAKGTLWTIIREIGLTIDELKDLL
Download Length: 225 bp
>T198192 NZ_CP096842:c3665363-3664935 [Mycobacterium tuberculosis variant bovis]
ATGCGAGCGCTGTTGGACGTCAACGTGCTACTGGCGCTGTTGGACCGCGATCACGTCGACCACGAGCGCGCCCGAGCGTG
GATCACCGGGCAGATCGAGCGGGGATGGGCTTCCTGTGCGATCACCCAAAACGGGTTCGTCCGCGTCATCAGCCAACCGC
GCTATCCCAGCCCAATCTCGGTAGCCCATGCCATCGACTTGTTGGCTCGTGCGACGCACACGCGCTATCACGAGTTCTGG
TCCTGCACCGTCAGCATTCTCGACTCAAAGGTCATCGATCGTTCCCGCCTGCACAGCCCCAAACAGGTCACCGACGCGTA
CTTGCTGGCCCTCGCGGTCGCTCATGATGGCCGATTTGTCACCTTCGATCAGTCGATTGCGTTGACTGCGGTTCCTGGCG
CAACCAAACAGCACCTGGCAACGCTGTAG
ATGCGAGCGCTGTTGGACGTCAACGTGCTACTGGCGCTGTTGGACCGCGATCACGTCGACCACGAGCGCGCCCGAGCGTG
GATCACCGGGCAGATCGAGCGGGGATGGGCTTCCTGTGCGATCACCCAAAACGGGTTCGTCCGCGTCATCAGCCAACCGC
GCTATCCCAGCCCAATCTCGGTAGCCCATGCCATCGACTTGTTGGCTCGTGCGACGCACACGCGCTATCACGAGTTCTGG
TCCTGCACCGTCAGCATTCTCGACTCAAAGGTCATCGATCGTTCCCGCCTGCACAGCCCCAAACAGGTCACCGACGCGTA
CTTGCTGGCCCTCGCGGTCGCTCATGATGGCCGATTTGTCACCTTCGATCAGTCGATTGCGTTGACTGCGGTTCCTGGCG
CAACCAAACAGCACCTGGCAACGCTGTAG
Antitoxin
Download Length: 71 a.a. Molecular weight: 7634.57 Da Isoelectric Point: 4.2258
>AT198192 WP_211432824.1 NZ_CP072635:661872-662084 [Chloracidobacterium sp. D]
MKYRVFIEQDEDNVYVATAPSLPGCVSQGKTRSEALENIKEAITGYLESLKAHGEPVPPPISEEIVDVSS
MKYRVFIEQDEDNVYVATAPSLPGCVSQGKTRSEALENIKEAITGYLESLKAHGEPVPPPISEEIVDVSS
Download Length: 213 bp
>AT198192 NZ_CP096842:c3665609-3665367 [Mycobacterium tuberculosis variant bovis]
ATGCGCACCACGTTGTCCATCGACGACGATGTATTGCTGGCCGTGAAGGAACGGGCACGCAGGGAGAAGCGCACCGCGGG
TGAAATCCTGTCGGATCTGGCCCGGCAAGCGTTAACCAACCAGAATCCCCAGCCTGCGGCGAGCCAGGAGGACGCCTTTC
ATGGCTTCGAACCCCTGCCTCATCGCGGTGGAGCGGTATCGAACGCGCTGATCGATCGGCTTCGTGACGAGGAGGCCGTG
TGA
ATGCGCACCACGTTGTCCATCGACGACGATGTATTGCTGGCCGTGAAGGAACGGGCACGCAGGGAGAAGCGCACCGCGGG
TGAAATCCTGTCGGATCTGGCCCGGCAAGCGTTAACCAACCAGAATCCCCAGCCTGCGGCGAGCCAGGAGGACGCCTTTC
ATGGCTTCGAACCCCTGCCTCATCGCGGTGGAGCGGTATCGAACGCGCTGATCGATCGGCTTCGTGACGAGGAGGCCGTG
TGA