Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/RHH(antitoxin)
Location 2190292..2190845 Replicon chromosome
Accession NZ_CP072610
Organism Pseudomonas wenzhouensis strain A20

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag J7655_RS10060 Protein ID WP_230927614.1
Coordinates 2190552..2190845 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag J7655_RS10055 Protein ID WP_230927613.1
Coordinates 2190292..2190564 (+) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J7655_RS10030 (J7655_09995) 2185882..2186298 + 417 WP_230927610.1 hypothetical protein -
J7655_RS10035 (J7655_10000) 2186284..2187237 - 954 WP_230927611.1 IS1595-like element ISAchd1 family transposase -
J7655_RS10040 2187250..2187573 + 324 WP_230927612.1 hypothetical protein -
J7655_RS10045 (J7655_10010) 2187733..2189247 + 1515 WP_230925725.1 IS21 family transposase -
J7655_RS10050 (J7655_10015) 2189265..2190020 + 756 WP_230925724.1 IS21-like element ISPpu7 family helper ATPase IstB -
J7655_RS10055 (J7655_10020) 2190292..2190564 + 273 WP_230927613.1 CopG family ribbon-helix-helix protein Antitoxin
J7655_RS10060 (J7655_10025) 2190552..2190845 + 294 WP_230927614.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
J7655_RS10065 (J7655_10030) 2190839..2192248 - 1410 WP_230927615.1 site-specific integrase -
J7655_RS10070 (J7655_10035) 2192595..2192687 - 93 Protein_1976 integrase -
J7655_RS10075 (J7655_10040) 2192813..2193133 + 321 WP_230927616.1 helix-hairpin-helix domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2120834..2202358 81524


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-95)

Antitoxin

Ribbon-helix-helix protein, CopG

(3-40)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11169.64 Da        Isoelectric Point: 5.9081

>T198163 WP_230927614.1 NZ_CP072610:2190552-2190845 [Pseudomonas wenzhouensis]
VPRLIVTEGAAKGLERCRRFLADKDPQVARRAAQAIERQFTRLEESPEVGRPFPDLPELRELIIEFGDSGYVALYRYERA
DDTAYVLAFRHQKEAGY

Download         Length: 294 bp

>T198163 NZ_CP096842:c1574933-1574532 [Mycobacterium tuberculosis variant bovis]
ATGATCCTTGTCGACTCCGATGTGCTGATCGCGCATTTGCGGGGTGTCGTTGCTGCTCGCGATTGGCTTGTCAGCGCCCG
CAAGGACGGACCGCTGGCGATCAGCGTGGTGTCCACCGCCGAACTCATCGGCGGAATGCGGACCGCCGAACGGCGCGAGG
TGTGGCGCCTGCTTGCATCGTTTCGGGTACAGCCAGCAACCGAGGTAATCGCACGCCGCGCCGGCGACATGATGCGCCGA
TATCGTCGCAGCCACAACCGGATTGGACTTGGCGACTATCTGATAGCTGCTACCGCCGACGTCCAGGGCCTGCAATTGGC
AACCCTCAACGTGTGGCATTTCCCCATGTTCGAGCAGCTGAAACCACCATTTGCGGTGCCGGGGCACCGACCGCGGGCAT
GA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10397.58 Da        Isoelectric Point: 6.0787

>AT198163 WP_230927613.1 NZ_CP072610:2190292-2190564 [Pseudomonas wenzhouensis]
MATSIKIDDDLKGRIQHLAGLRQRSSHWIMREAIIQYVEREEARESFKQEALASWAAYQETGRHLTGQETRTWLGSWGTD
AEAELPKCHD

Download         Length: 273 bp

>AT198163 NZ_CP096842:c1575187-1574930 [Mycobacterium tuberculosis variant bovis]
ATGAAGCGGACCAACATCTACCTCGACGAGGAGCAGACGGCAAGCCTCGACAAGTTGGCCGCGCAAGAAGGTGTTTCGCG
CGCCGAGCTGATCCGCCTCCTGCTGAACCGAGCCCTCACCACCGCTGGGGACGACCTTGCATCGGACCTGCAGGCTATAA
ACGATTCGTTCGGCACGCTTCGCCACCTGGATCCGCCGGTGCGTCGCTCCGGTGGTCGTGAACAGCACCTTGCCCAGGTG
TGGCGCGCCACCTCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References