Detailed information of TA system TA198158

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-RelB
• Location: 115859..116375
• Replicon: chromosome
• Accession: NZ_CP072610
• Organism: Pseudomonas wenzhouensis strain A20

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: J7655_RS00545
• Protein ID: WP_230926100.1
• Coordinates: 115859..116146 (-)
• Length: 96 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: J7655_RS00550
• Protein ID: WP_084314717.1
• Coordinates: 116136..116375 (-)
• Length: 80 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
J7655_RS00530 (J7655_00525)	111195..111815	+	621	WP_230926097.1	lysophospholipid acyltransferase family protein	-
J7655_RS00535 (J7655_00530)	111817..112749	+	933	WP_230926098.1	phosphatidate cytidylyltransferase	-
J7655_RS00540 (J7655_00535)	113433..115820	-	2388	WP_230926099.1	DEAD/DEAH box helicase family protein	-
J7655_RS00545 (J7655_00540)	115859..116146	-	288	WP_230926100.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
J7655_RS00550 (J7655_00545)	116136..116375	-	240	WP_084314717.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
J7655_RS00555 (J7655_00550)	116805..117206	-	402	WP_230926101.1	hypothetical protein	-
J7655_RS00560 (J7655_00555)	117432..118235	-	804	WP_010454871.1	IS21-like element ISPst3 family helper ATPase IstB	-
J7655_RS00565 (J7655_00560)	118228..119727	-	1500	WP_230927644.1	IS21-like element ISPst3 family transposase	-
J7655_RS00570 (J7655_00565)	119934..120407	-	474	WP_230926102.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Integrative and Conjugative Element	-	-	22033..258337	236304

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-83)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (1-70)

Sequences

Toxin

Protein

• Length: 96 a.a.
• Molecular weight: 11270.08 Da
• Isoelectric Point: 10.0978

>T198158 WP_230926100.1 NZ_CP072610:c116146-115859 [Pseudomonas wenzhouensis]
MTYSLEFDARALKEWHKLGDTVREQLKKKLAEVLVNPRVEANRLHSLPDCYKIKLRSSGYRLVYQVIDHEVVVFVVAVDR
REREQAYRKAAERLK

Nucleotide

• Length: 288 bp

>T198158 NZ_CP096842:c1232064-1231753 [Mycobacterium tuberculosis variant bovis]
ATGCGACCTATCCACATCGCACAGCTTGACAAGGCTAGACCCGTCCTGATCCTTACCCGCGAGGTCGTACGTCCGCACCT
CACGAACGTCACCGTCGCCCCGATCACGACAACCGTGCGTGGGCTAGCCACCGAAGTCCCGGTAGACGCGGTGAACGGGC
TGAATCAACCGTCAGTCGTCAGCTGCGACAACATCCAAACGATCCCGGTGTGTGACCTTGGTCGTCAAATCGGCTACCTG
CTCGCGTCGCAGGAGCCGGCTCTAGCCGAGGCCATCGGCAACGCGTTCGACCTCGATTGGGTGGTGGCATAG

Antitoxin

Protein

• Length: 80 a.a.
• Molecular weight: 9066.51 Da
• Isoelectric Point: 4.8279

>AT198158 WP_084314717.1 NZ_CP072610:c116375-116136 [Pseudomonas wenzhouensis]
MASINIRIDDELKVRAYRELEKLGVTPSELMRQALQYVAERGQLPFRPVLMTEEDEALIATVRERLAAPQRVKVSLDDL

Nucleotide

• Length: 240 bp

>AT198158 NZ_CP096842:c1232384-1232064 [Mycobacterium tuberculosis variant bovis]
ATGTACCTACCCTGGGGGGTCGTCCTCGCCGGCGGCGCGAACGGTTTTGGGGCGGGTGCATACCAAACTGGTACCATCTG
TGAAGTGAGTACACAGATTGCGGTTCGCTTGCCCGATGAGATTGTCGCGTTCATCGACGACGAAGTCCGGGGACAGCATG
CCCGTAGCCGTGCGGCTGTCGTGCTGCGGGCGCTGGAACGGGAACGCCGCCGTCGTCTCGCCGAACGCGACGCGGAGATC
CTCGCCACCAACACGTCAGCCACGGGTGATCTGGATACGCTGGCCGGCCACTGCGCTCGTACCGCCCTCGACATCGACTG
A