Detailed information of TA system TA198156

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 2492424..2492955
• Replicon: chromosome
• Accession: NZ_CP072608
• Organism: Desulfovibrio desulfuricans strain L4

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: J8J02_RS10705
• Protein ID: WP_209817829.1
• Coordinates: 2492424..2492720 (-)
• Length: 99 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: J8J02_RS10710
• Protein ID: WP_209817830.1
• Coordinates: 2492710..2492955 (-)
• Length: 82 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
J8J02_RS10675 (J8J02_10675)	2487633..2489276	-	1644	WP_209817819.1	hypothetical protein	-
J8J02_RS10680 (J8J02_10680)	2489303..2489698	-	396	WP_209817820.1	type II toxin-antitoxin system death-on-curing family toxin	-
J8J02_RS10685 (J8J02_10685)	2489695..2489931	-	237	WP_209817822.1	hypothetical protein	-
J8J02_RS10690 (J8J02_10690)	2489994..2491028	-	1035	WP_209817824.1	DUF3150 domain-containing protein	-
J8J02_RS10695 (J8J02_10695)	2491038..2492063	-	1026	WP_209817825.1	AAA family ATPase	-
J8J02_RS10700 (J8J02_10700)	2492164..2492364	-	201	WP_209817827.1	hypothetical protein	-
J8J02_RS10705 (J8J02_10705)	2492424..2492720	-	297	WP_209817829.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
J8J02_RS10710 (J8J02_10710)	2492710..2492955	-	246	WP_209817830.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
J8J02_RS10715 (J8J02_10715)	2493023..2493385	-	363	WP_209817832.1	hypothetical protein	-
J8J02_RS10720 (J8J02_10720)	2493402..2494565	-	1164	WP_209817834.1	hypothetical protein	-
J8J02_RS10725 (J8J02_10725)	2494634..2495335	-	702	WP_209817836.1	ERF family protein	-
J8J02_RS10730 (J8J02_10730)	2495729..2496229	-	501	WP_209817838.1	A24 family peptidase	-
J8J02_RS10735 (J8J02_10735)	2496345..2496917	-	573	WP_209817840.1	lytic transglycosylase domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	2478242..2528690	50448

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-82)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (9-69)

Sequences

Toxin

Protein

• Length: 99 a.a.
• Molecular weight: 11765.77 Da
• Isoelectric Point: 10.3662

>T198156 WP_209817829.1 NZ_CP072608:c2492720-2492424 [Desulfovibrio desulfuricans]
MSYSLQFHELALKEWKKLDVSIREQFKKKLAERLQQPRVPSSTLSDMRDCYKIKLRSIGYRLVYKVNDDILFVTVISIGK
RERLEAYRQALRRMPSEE

Nucleotide

• Length: 297 bp

>T198156 NZ_CP096842:1015165-1015599 [Mycobacterium tuberculosis variant bovis]
ATGGCGAAACTGTCCGGATCCATCGACGTACCGCTGCCACCGGAGGAAGCCTGGATGCACGCCTCCGATCTGACTCGTTA
CCGAGAGTGGCTGACCATCCACAAGGTATGGCGCAGCAAGTTGCCCGAAGTGCTCGAGAAGGGCACGGTCGTCGAGTCGT
ATGTCGAGGTCAAGGGCATGCCCAACCGGATCAAGTGGACGATCGTGCGGTACAAACCCCCGGAGGGCATGACGCTCAAC
GGCGACGGTGTGGGTGGTGTCAAAGTCAAGCTGATCGCTAAGGTAGCGCCGAAAGAGCACGGCTCCGTCGTCAGCTTCGA
TGTGCACCTCGGCGGCCCGGCCCTGCTCGGGCCGATCGGCATGATCGTCGCCGCTGCATTGCGAGCCGACATCCGCGAAT
CGCTGCAGAACTTCGTCACGGTGTTTGCCGGCTGA

Antitoxin

Protein

• Length: 82 a.a.
• Molecular weight: 9102.37 Da
• Isoelectric Point: 4.8259

>AT198156 WP_209817830.1 NZ_CP072608:c2492955-2492710 [Desulfovibrio desulfuricans]
MDSIHSNITVSVTELKRNFANVLATAKDAPVAVLNHNKPEAYLLSAKHYEEILGILEDLEDRKIVEKRDDGPFVKVTLDE
L

Nucleotide

• Length: 246 bp

>AT198156 NZ_CP096842:1014980-1015159 [Mycobacterium tuberculosis variant bovis]
ATGGGAATCCTGGACAAGGTAAAGAACCTGCTGTCGCAGAACGCCGACAAGGTCGAGACGGTGATCAACAAAGCGGGCGA
ATTCGTCGACGAGCAGACGCAAGGCAATTATTCTGACGCCATCCACAAGCTGCAGGACGCGGCCAGCAACGTCGTCGGCA
TGAGCGACCAGCAGAGCTAG