Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RHH(antitoxin)
Location 55772..56288 Replicon chromosome
Accession NZ_CP072608
Organism Desulfovibrio desulfuricans strain L4

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag J8J02_RS00250 Protein ID WP_209818413.1
Coordinates 56001..56288 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag J8J02_RS00245 Protein ID WP_209818411.1
Coordinates 55772..56011 (+) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J8J02_RS00225 (J8J02_00225) 51614..51766 - 153 WP_209818405.1 hypothetical protein -
J8J02_RS00230 (J8J02_00230) 51998..53629 - 1632 WP_209818406.1 hypothetical protein -
J8J02_RS00235 (J8J02_00235) 53634..54668 - 1035 WP_209818408.1 DUF3150 domain-containing protein -
J8J02_RS00240 (J8J02_00240) 54678..55703 - 1026 WP_209818409.1 AAA family ATPase -
J8J02_RS00245 (J8J02_00245) 55772..56011 + 240 WP_209818411.1 ribbon-helix-helix protein, CopG family Antitoxin
J8J02_RS00250 (J8J02_00250) 56001..56288 + 288 WP_209818413.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
J8J02_RS00255 (J8J02_00255) 56289..56651 - 363 WP_209818414.1 hypothetical protein -
J8J02_RS00260 (J8J02_00260) 56668..57831 - 1164 WP_209818415.1 hypothetical protein -
J8J02_RS00265 (J8J02_00265) 57900..58601 - 702 WP_209818416.1 ERF family protein -
J8J02_RS00270 (J8J02_00270) 59119..61020 + 1902 WP_209818418.1 Dam family site-specific DNA-(adenine-N6)-methyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 49071..65033 15962


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-93)

Antitoxin

Ribbon-helix-helix protein, CopG

(4-40)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 10584.17 Da        Isoelectric Point: 10.1609

>T198155 WP_209818413.1 NZ_CP072608:56001-56288 [Desulfovibrio desulfuricans]
MQNSPVRWLALAIADLHDIAGFLAETDSDAGRKIVQCVWNAGQSLASLSSRGRAGRVAGTRELVLTEFPYFIAYRVVKSE
VQILRVLHTARRYPQ

Download         Length: 288 bp

>T198155 NZ_CP096842:843148-843576 [Mycobacterium tuberculosis variant bovis]
ATGTTCCTTCTCGACGCCAACGTGCTGCTGGCTGCACACCGCGGTGACCACCCGAATCACCGAACCGTCCGCCCCTGGTT
CGATCGACTGCTCGCGGCTGACGACCCCTTCACAGTGCCGAACCTGGTATGGGCGTCGTTCCTCCGGCTGGCAACGAATC
GACGCATCTTCGAGATTCCGTCACCGCGAGCAGAGACATTCGCATTCGTCGAAGCCGTCACCGCCCAGCCCCATCACCTT
CCGACGAACCCCGGTCCCAGACACCTGGTGCTGCTGCGAAAACTCTGCGACGAGGCCGACGCATCGGGCGACTTGATACC
TGACGCGGTACTCGCGGCCATAGCAGTGGGGCATCACTGCGCCGTGGTGAGCCTGGACAGGGATTTCGCCCGGTTTGCCT
CGGTGCGCCACATTCGCCCGCCGCTCTAG

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8796.71 Da        Isoelectric Point: 4.7513

>AT198155 WP_209818411.1 NZ_CP072608:55772-56011 [Desulfovibrio desulfuricans]
MSTVTARLDTDTQAQLEKLAAATSRSRSWLVAEAVRQYVAEQSWQVEAIQEGVRQADEGKFASDQEVTEAFARWGVHAK

Download         Length: 240 bp

>AT198155 NZ_CP096842:842867-843124 [Mycobacterium tuberculosis variant bovis]
ATGCGCACCACGGTGTCAATCTCCGATGAAATACTCGCTGCCGCCAAACGCCGGGCCCGCGAGCGTGGTCAATCGCTGGG
CGCTGTGATCGAGGACGCCCTTCGGCGGGAGTTCGCCGCCGCCCACGTCGGCGGCGCCCGCCCGACCGTCCCGGTTTTCG
ACGGCGGCACCGGTCCGCGGCGAGGCATCGACCTGACCTCGAATAGAGCGTTGTCCGAAGTGCTCGACGAGGGCCTGGAA
CTGAACTCCCGGAAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References