Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2051608..2051879 Replicon chromosome
Accession NZ_CP072565
Organism Escherichia coli strain WG5::PA8

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2051738..2051841 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2051608..2051879 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J8F86_RS09830 2048163..2048825 - 663 WP_000944258.1 exodeoxyribonuclease X -
J8F86_RS09835 2048849..2049505 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
J8F86_RS09840 2049607..2049837 - 231 WP_000916763.1 DNA polymerase III subunit theta -
J8F86_RS09845 2049976..2050350 + 375 WP_000168747.1 CopC domain-containing protein YobA -
J8F86_RS09850 2050354..2051226 + 873 WP_000879295.1 copper homeostasis membrane protein CopD -
J8F86_RS09855 2051239..2051580 + 342 WP_000976472.1 YebY family protein -
- 2051608..2051879 - 272 - - Antitoxin
- 2051738..2051841 + 104 - - Toxin
J8F86_RS09860 2051976..2052632 + 657 WP_000812732.1 protein-serine/threonine phosphatase -
J8F86_RS09865 2052633..2052824 - 192 WP_001338167.1 YebW family protein -
J8F86_RS09870 2052929..2053165 - 237 WP_001338166.1 YebV family protein -
J8F86_RS09875 2053283..2054722 - 1440 WP_001351758.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T198078 NZ_CP072565:2051738-2051841 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT198078 NZ_CP072565:c2051879-2051608 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References