Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4439856..4440001 Replicon chromosome
Accession NZ_CP072555
Organism Klebsiella pneumoniae strain KP2648

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4439892..4439994 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4439856..4440001 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J7339_RS21765 (J7339_21715) 4434986..4437046 + 2061 WP_004151449.1 oligopeptidase B -
J7339_RS21770 (J7339_21720) 4437050..4437709 - 660 WP_002911407.1 exodeoxyribonuclease X -
J7339_RS21775 (J7339_21725) 4437788..4438018 - 231 WP_002911406.1 DNA polymerase III subunit theta -
J7339_RS21780 (J7339_21730) 4438131..4438505 + 375 WP_004151448.1 CopC domain-containing protein YobA -
J7339_RS21785 (J7339_21735) 4438509..4439378 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
J7339_RS21790 (J7339_21740) 4439395..4439733 + 339 WP_002911404.1 YebY family protein -
- 4439856..4440001 - 146 - - Antitoxin
- 4439892..4439994 + 103 - - Toxin
J7339_RS21795 (J7339_21745) 4440369..4440512 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
J7339_RS21800 (J7339_21750) 4440617..4441585 - 969 WP_004151446.1 VirK/YbjX family protein -
J7339_RS21805 (J7339_21755) 4441742..4442395 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
J7339_RS21810 (J7339_21760) 4442392..4442583 - 192 WP_002911395.1 YebW family protein -
J7339_RS21815 (J7339_21765) 4442681..4442920 - 240 WP_002911393.1 YebV family protein -
J7339_RS21820 (J7339_21770) 4443036..4444469 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T198027 NZ_CP072555:4439892-4439994 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT198027 NZ_CP072555:c4440001-4439856 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References