198010

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 1465834..1466379 Replicon chromosome
Accession NZ_CP072548
Organism Aggregatibacter sp. 2125159857

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag J5X96_RS07260 Protein ID WP_209362690.1
Coordinates 1465834..1466106 (-) Length 91 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag J5X96_RS07265 Protein ID WP_209362692.1
Coordinates 1466107..1466379 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J5X96_RS07240 (J5X96_07240) 1461743..1463239 - 1497 WP_209362686.1 transcription termination factor NusA -
J5X96_RS07245 (J5X96_07245) 1463262..1463717 - 456 WP_021616648.1 ribosome maturation factor RimP -
J5X96_RS07255 (J5X96_07255) 1464070..1465740 - 1671 WP_209362688.1 glutamine--tRNA ligase -
J5X96_RS07260 (J5X96_07260) 1465834..1466106 - 273 WP_209362690.1 type II toxin-antitoxin system YafQ family toxin Toxin
J5X96_RS07265 (J5X96_07265) 1466107..1466379 - 273 WP_209362692.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
J5X96_RS07270 (J5X96_07270) 1466587..1467762 + 1176 WP_209362693.1 efflux RND transporter periplasmic adaptor subunit -
J5X96_RS07275 (J5X96_07275) 1467782..1469713 + 1932 WP_209362695.1 MacB family efflux pump subunit -
J5X96_RS07280 (J5X96_07280) 1469801..1471171 + 1371 WP_209362697.1 TolC family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(1-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(4-82)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10616.29 Da        Isoelectric Point: 9.5300

>T198010 WP_209362690.1 NZ_CP072548:c1466106-1465834 [Aggregatibacter sp. 2125159857]
MKISFTKDYKRDLKRLANQPEILLSTEMIDVMHHLLNGKNLPEKYKDHALSGNWKGFRDCHIKNDLVLIYHVNNEGLTLV
RLNTHSEVFR

Download         Length: 273 bp

>T198010 NZ_CP096839:2841979-2842356 [Mycobacterium tuberculosis variant bovis]
GTGAAGCTGATCGACACCACCATCGCGGTCGACCACCTTCGCGGCGAACCCGCGGCAGCCGTGCTGCTCGCCGAACTGAT
AAACAACGGTGAGGAGATCGCGGCCAGCGAGCTGGTCCGATTCGAACTCCTCGCCGGTGTGCGGGAAAGCGAACTCGCGG
CGCTCGAGGCCTTCTTCTCGGCAGTGGTGTGGACCCTGGTGACCGAGGACATTGCCCGGATCGGCGGACGACTCGCCCGT
CGATACCGGTCCAGCCACCGCGGTATCGACGACGTGGACTACCTGATCGCTGCGACCGCCATTGTGGTCGACGCCGACCT
GCTCACCACCAATGTGCGCCACTTCCCGATGTTCCCGGATCTGCAGCCGCCGTACTGA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10262.80 Da        Isoelectric Point: 5.1106

>AT198010 WP_209362692.1 NZ_CP072548:c1466379-1466107 [Aggregatibacter sp. 2125159857]
MTSYTFRLDPELKEQAFSVFRSYGLNPAQALKMILQQVVSTKSIPVQLDYQPNETTIRAMKDVLNGKVESIEAENVEELI
KKMQRVANEA

Download         Length: 273 bp

>AT198010 NZ_CP096839:2841725-2841982 [Mycobacterium tuberculosis variant bovis]
ATGCGGACTCAGGTGACCCTGGGCAAAGAGGAGCTTGAGCTGCTCGATCGTGCCGCCAAGGCGAGTGGCGCATCGCGGTC
CGAACTCATCCGACGCGCAATTCACCGTGCCTACGGGACTGGATCCAAGCAGGAACGGCTCGCCGCGCTCGACCACAGCC
GTGGCTCGTGGCGAGGACGGGACTTCACCGGCACCGAGTATGTCGACGCCATTCGGGGCGACCTCAACGAACGACTTGCT
CGGCTCGGTCTGGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References