Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1997614..1997759 Replicon chromosome
Accession NZ_CP072496
Organism Klebsiella pneumoniae strain KPN247

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1997650..1997752 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1997614..1997759 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J5253_RS09705 (J5253_09705) 1992744..1994804 + 2061 WP_004151449.1 oligopeptidase B -
J5253_RS09710 (J5253_09710) 1994808..1995467 - 660 WP_002911407.1 exodeoxyribonuclease X -
J5253_RS09715 (J5253_09715) 1995546..1995776 - 231 WP_002911406.1 DNA polymerase III subunit theta -
J5253_RS09720 (J5253_09720) 1995889..1996263 + 375 WP_004151448.1 CopC domain-containing protein YobA -
J5253_RS09725 (J5253_09725) 1996267..1997136 + 870 WP_159195797.1 copper homeostasis membrane protein CopD -
J5253_RS09730 (J5253_09730) 1997153..1997491 + 339 WP_167803391.1 YebY family protein -
- 1997614..1997759 - 146 - - Antitoxin
- 1997650..1997752 + 103 - - Toxin
J5253_RS09735 (J5253_09735) 1998127..1998270 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
J5253_RS09740 (J5253_09740) 1998375..1999343 - 969 WP_004151446.1 VirK/YbjX family protein -
J5253_RS09745 (J5253_09745) 1999500..2000153 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
J5253_RS09750 (J5253_09750) 2000150..2000341 - 192 WP_002911395.1 YebW family protein -
J5253_RS09755 (J5253_09755) 2000439..2000678 - 240 WP_002911393.1 YebV family protein -
J5253_RS09760 (J5253_09760) 2000794..2002227 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T197923 NZ_CP072496:1997650-1997752 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT197923 NZ_CP072496:c1997759-1997614 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References