Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3052738..3052883 Replicon chromosome
Accession NZ_CP072494
Organism Klebsiella pneumoniae strain KPN246

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3052745..3052847 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3052738..3052883 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J7V84_RS14905 3048270..3049703 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
J7V84_RS14910 3049819..3050058 + 240 WP_002911393.1 YebV family protein -
J7V84_RS14915 3050156..3050347 + 192 WP_002911395.1 YebW family protein -
J7V84_RS14920 3050344..3050997 - 654 WP_004175436.1 protein-serine/threonine phosphatase -
J7V84_RS14925 3051154..3052122 + 969 WP_074181864.1 VirK/YbjX family protein -
J7V84_RS14930 3052227..3052370 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 3052738..3052883 + 146 - - Antitoxin
- 3052745..3052847 - 103 - - Toxin
J7V84_RS14935 3053006..3053344 - 339 WP_002911404.1 YebY family protein -
J7V84_RS14940 3053361..3054230 - 870 WP_004151447.1 copper homeostasis membrane protein CopD -
J7V84_RS14945 3054234..3054608 - 375 WP_004151448.1 CopC domain-containing protein YobA -
J7V84_RS14950 3054721..3054951 + 231 WP_002911406.1 DNA polymerase III subunit theta -
J7V84_RS14955 3055030..3055689 + 660 WP_002911407.1 exodeoxyribonuclease X -
J7V84_RS14960 3055693..3057753 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T197903 NZ_CP072494:c3052847-3052745 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT197903 NZ_CP072494:3052738-3052883 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References