Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2004784..2004929 Replicon chromosome
Accession NZ_CP072492
Organism Klebsiella pneumoniae strain KPN236

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2004820..2004922 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2004784..2004929 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J7V87_RS09435 1999914..2001974 + 2061 WP_004151449.1 oligopeptidase B -
J7V87_RS09440 2001978..2002637 - 660 WP_002911407.1 exodeoxyribonuclease X -
J7V87_RS09445 2002716..2002946 - 231 WP_002911406.1 DNA polymerase III subunit theta -
J7V87_RS09450 2003059..2003433 + 375 WP_004151448.1 CopC domain-containing protein YobA -
J7V87_RS09455 2003437..2004306 + 870 WP_014907333.1 copper homeostasis membrane protein CopD -
J7V87_RS09460 2004323..2004661 + 339 WP_002911404.1 YebY family protein -
- 2004784..2004929 - 146 - - Antitoxin
- 2004820..2004922 + 103 - - Toxin
J7V87_RS09465 2005297..2005440 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
J7V87_RS09470 2005545..2006513 - 969 WP_014907334.1 VirK/YbjX family protein -
J7V87_RS09475 2006670..2007323 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
J7V87_RS09480 2007320..2007511 - 192 WP_002911395.1 YebW family protein -
J7V87_RS09485 2007609..2007848 - 240 WP_002911393.1 YebV family protein -
J7V87_RS09490 2007964..2009397 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T197883 NZ_CP072492:2004820-2004922 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT197883 NZ_CP072492:c2004929-2004784 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References