Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2070679..2070824 Replicon chromosome
Accession NZ_CP072463
Organism Klebsiella pneumoniae strain KP1517

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2070715..2070817 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2070679..2070824 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HRG83_RS10220 (HRG83_10220) 2065809..2067869 + 2061 WP_004151449.1 oligopeptidase B -
HRG83_RS10225 (HRG83_10225) 2067873..2068532 - 660 WP_002911407.1 exodeoxyribonuclease X -
HRG83_RS10230 (HRG83_10230) 2068611..2068841 - 231 WP_002911406.1 DNA polymerase III subunit theta -
HRG83_RS10235 (HRG83_10235) 2068954..2069328 + 375 WP_004151448.1 CopC domain-containing protein YobA -
HRG83_RS10240 (HRG83_10240) 2069332..2070201 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
HRG83_RS10245 (HRG83_10245) 2070218..2070556 + 339 WP_002911404.1 YebY family protein -
- 2070679..2070824 - 146 - - Antitoxin
- 2070715..2070817 + 103 - - Toxin
HRG83_RS10250 (HRG83_10250) 2071192..2071335 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
HRG83_RS10255 (HRG83_10255) 2071440..2072408 - 969 WP_004151446.1 VirK/YbjX family protein -
HRG83_RS10260 (HRG83_10260) 2072565..2073218 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
HRG83_RS10265 (HRG83_10265) 2073215..2073406 - 192 WP_002911395.1 YebW family protein -
HRG83_RS10270 (HRG83_10270) 2073504..2073743 - 240 WP_002911393.1 YebV family protein -
HRG83_RS10275 (HRG83_10275) 2073859..2075292 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T197837 NZ_CP072463:2070715-2070817 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT197837 NZ_CP072463:c2070824-2070679 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References