Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1918215..1918360 Replicon chromosome
Accession NZ_CP072456
Organism Klebsiella pneumoniae strain b1-2L

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1918251..1918353 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1918215..1918360 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J7V71_RS09320 1913345..1915405 + 2061 WP_004151449.1 oligopeptidase B -
J7V71_RS09325 1915409..1916068 - 660 WP_002911407.1 exodeoxyribonuclease X -
J7V71_RS09330 1916147..1916377 - 231 WP_002911406.1 DNA polymerase III subunit theta -
J7V71_RS09335 1916490..1916864 + 375 WP_004151448.1 CopC domain-containing protein YobA -
J7V71_RS09340 1916868..1917737 + 870 WP_020956678.1 copper homeostasis membrane protein CopD -
J7V71_RS09345 1917754..1918092 + 339 WP_002911404.1 YebY family protein -
- 1918215..1918360 - 146 - - Antitoxin
- 1918251..1918353 + 103 - - Toxin
J7V71_RS09350 1918728..1918871 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
J7V71_RS09355 1918976..1919944 - 969 WP_004151446.1 VirK/YbjX family protein -
J7V71_RS09360 1920101..1920754 + 654 WP_020802220.1 protein-serine/threonine phosphatase -
J7V71_RS09365 1920751..1920942 - 192 WP_002911395.1 YebW family protein -
J7V71_RS09370 1921040..1921279 - 240 WP_002911393.1 YebV family protein -
J7V71_RS09375 1921395..1922828 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T197794 NZ_CP072456:1918251-1918353 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT197794 NZ_CP072456:c1918360-1918215 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References