Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-dinJ/YafQ-RelB
Location 1394443..1394974 Replicon chromosome
Accession NZ_CP072455
Organism Xenorhabdus budapestensis strain C-7-2

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag HGO23_RS06725 Protein ID WP_099137432.1
Coordinates 1394693..1394974 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name dinJ Uniprot ID -
Locus tag HGO23_RS06720 Protein ID WP_099137431.1
Coordinates 1394443..1394706 (+) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HGO23_RS06700 (HGO23_06700) 1390784..1391152 + 369 WP_209026930.1 phage tail tube protein -
HGO23_RS06705 (HGO23_06705) 1391162..1391458 + 297 WP_209028374.1 phage tail assembly protein -
HGO23_RS06710 (HGO23_06710) 1391576..1393486 + 1911 WP_209028375.1 hypothetical protein -
HGO23_RS06715 (HGO23_06715) 1393817..1394302 + 486 WP_099137483.1 hypothetical protein -
HGO23_RS06720 (HGO23_06720) 1394443..1394706 + 264 WP_099137431.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
HGO23_RS06725 (HGO23_06725) 1394693..1394974 + 282 WP_099137432.1 type II toxin-antitoxin system YafQ family toxin Toxin
HGO23_RS06730 (HGO23_06730) 1395077..1396486 + 1410 WP_209028376.1 DNA circularization N-terminal domain-containing protein -
HGO23_RS06735 (HGO23_06735) 1396483..1397589 + 1107 WP_209026933.1 contractile injection system protein, VgrG/Pvc8 family -
HGO23_RS06740 (HGO23_06740) 1397573..1398160 + 588 WP_209026934.1 phage baseplate assembly protein -
HGO23_RS06745 (HGO23_06745) 1398157..1398603 + 447 WP_099137534.1 phage GP46 family protein -
HGO23_RS06750 (HGO23_06750) 1398593..1399732 + 1140 WP_209026935.1 baseplate J/gp47 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1357211..1423741 66530


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(2-93)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-83)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10820.23 Da        Isoelectric Point: 8.0705

>T197784 WP_099137432.1 NZ_CP072455:1394693-1394974 [Xenorhabdus budapestensis]
MRTIERSTAFKRDYKRESKGQYRVGLDDALVPVLVALANNEPLERRHRDHELDGNWSGYRECHIKPDLLLIYQKPDSETL
QLARLGSHSQLFG

Download         Length: 282 bp

>T197784 NZ_CP096713:16036-16392 [Acinetobacter baumannii]
ATGTGGACAGTCATTACAACGGATCTGTTTAATGAATGGCTTGAACAGCAAGATGAAGCAACACAAGAGAAAGTCTTAGC
TGCATTGGTTGTTCTACAACAGCAAGGGCCTAGTTTAGGTCGTCCTTTAGTAGATACCGTCTACGATTCTAAATTTACCA
ATATGAAGGAACTACGTGTTCAGCATCGTGGTAAACCGTTAAGGGCATTTTTTGCATTCGATCCCCTAAGACAAGCGATT
GTGCTGTGTATTGGTGATAAGAGTAATAAAAAGCGTTTTTATACAGAGATGCTAGCAATTGCAGATGAGCAATACGCACT
TCATCTCTCAACTTTAGGAGATCAATCTAATGGCTAA

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9738.08 Da        Isoelectric Point: 4.6926

>AT197784 WP_099137431.1 NZ_CP072455:1394443-1394706 [Xenorhabdus budapestensis]
MTTETYVRARIDAETKERARAALEAMGLSVSDAIRLLMLRIADEQRLPFDVRVPNATTQKAMEELEAGKGKRFDSVSALM
ADLHEDD

Download         Length: 264 bp

>AT197784 NZ_CP096713:16385-16687 [Acinetobacter baumannii]
ATGGCTAAGAGCTTACAAGAATTATTGGCTAGTCGCTCTCCAGAGAGTCAAGCTCGTATTCAAAAAATGGCTGATGAATT
ACTTTTAGAAAGTCAGCTTCACCTTATCCGAGAAGAGTTAGAAATTTCCCAGAAAGAACTAGCTGCAACCCTTGGAATTA
AACAGCCGTCATTATCAGCAATCGAAAATCGTGGTCATGATCTTAAAATTTCAACGATGAAAAAGTATGTTGAAGCAATG
GGTGGAAAACTTCGTATTGATGTAGAGCTTCCAACAGGAAAACACATAGGGTTCAATGTCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References