Detailed information of TA system TA197784

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relE-dinJ/YafQ-RelB
• Location: 1394443..1394974
• Replicon: chromosome
• Accession: NZ_CP072455
• Organism: Xenorhabdus budapestensis strain C-7-2

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: HGO23_RS06725
• Protein ID: WP_099137432.1
• Coordinates: 1394693..1394974 (+)
• Length: 94 a.a.

Antitoxin (Protein)

• Gene name: dinJ
• Uniprot ID: -
• Locus tag: HGO23_RS06720
• Protein ID: WP_099137431.1
• Coordinates: 1394443..1394706 (+)
• Length: 88 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HGO23_RS06700 (HGO23_06700)	1390784..1391152	+	369	WP_209026930.1	phage tail tube protein	-
HGO23_RS06705 (HGO23_06705)	1391162..1391458	+	297	WP_209028374.1	phage tail assembly protein	-
HGO23_RS06710 (HGO23_06710)	1391576..1393486	+	1911	WP_209028375.1	hypothetical protein	-
HGO23_RS06715 (HGO23_06715)	1393817..1394302	+	486	WP_099137483.1	hypothetical protein	-
HGO23_RS06720 (HGO23_06720)	1394443..1394706	+	264	WP_099137431.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
HGO23_RS06725 (HGO23_06725)	1394693..1394974	+	282	WP_099137432.1	type II toxin-antitoxin system YafQ family toxin	Toxin
HGO23_RS06730 (HGO23_06730)	1395077..1396486	+	1410	WP_209028376.1	DNA circularization N-terminal domain-containing protein	-
HGO23_RS06735 (HGO23_06735)	1396483..1397589	+	1107	WP_209026933.1	contractile injection system protein, VgrG/Pvc8 family	-
HGO23_RS06740 (HGO23_06740)	1397573..1398160	+	588	WP_209026934.1	phage baseplate assembly protein	-
HGO23_RS06745 (HGO23_06745)	1398157..1398603	+	447	WP_099137534.1	phage GP46 family protein	-
HGO23_RS06750 (HGO23_06750)	1398593..1399732	+	1140	WP_209026935.1	baseplate J/gp47 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	1357211..1423741	66530

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, YafQ-like toxin (2-93)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (1-83)

Sequences

Toxin

Protein

• Length: 94 a.a.
• Molecular weight: 10820.23 Da
• Isoelectric Point: 8.0705

>T197784 WP_099137432.1 NZ_CP072455:1394693-1394974 [Xenorhabdus budapestensis]
MRTIERSTAFKRDYKRESKGQYRVGLDDALVPVLVALANNEPLERRHRDHELDGNWSGYRECHIKPDLLLIYQKPDSETL
QLARLGSHSQLFG

Nucleotide

• Length: 282 bp

>T197784 NZ_CP096713:16036-16392 [Acinetobacter baumannii]
ATGTGGACAGTCATTACAACGGATCTGTTTAATGAATGGCTTGAACAGCAAGATGAAGCAACACAAGAGAAAGTCTTAGC
TGCATTGGTTGTTCTACAACAGCAAGGGCCTAGTTTAGGTCGTCCTTTAGTAGATACCGTCTACGATTCTAAATTTACCA
ATATGAAGGAACTACGTGTTCAGCATCGTGGTAAACCGTTAAGGGCATTTTTTGCATTCGATCCCCTAAGACAAGCGATT
GTGCTGTGTATTGGTGATAAGAGTAATAAAAAGCGTTTTTATACAGAGATGCTAGCAATTGCAGATGAGCAATACGCACT
TCATCTCTCAACTTTAGGAGATCAATCTAATGGCTAA

Antitoxin

Protein

• Length: 88 a.a.
• Molecular weight: 9738.08 Da
• Isoelectric Point: 4.6926

>AT197784 WP_099137431.1 NZ_CP072455:1394443-1394706 [Xenorhabdus budapestensis]
MTTETYVRARIDAETKERARAALEAMGLSVSDAIRLLMLRIADEQRLPFDVRVPNATTQKAMEELEAGKGKRFDSVSALM
ADLHEDD

Nucleotide

• Length: 264 bp

>AT197784 NZ_CP096713:16385-16687 [Acinetobacter baumannii]
ATGGCTAAGAGCTTACAAGAATTATTGGCTAGTCGCTCTCCAGAGAGTCAAGCTCGTATTCAAAAAATGGCTGATGAATT
ACTTTTAGAAAGTCAGCTTCACCTTATCCGAGAAGAGTTAGAAATTTCCCAGAAAGAACTAGCTGCAACCCTTGGAATTA
AACAGCCGTCATTATCAGCAATCGAAAATCGTGGTCATGATCTTAAAATTTCAACGATGAAAAAGTATGTTGAAGCAATG
GGTGGAAAACTTCGTATTGATGTAGAGCTTCCAACAGGAAAACACATAGGGTTCAATGTCTAA