Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | ccdAB/CcdA(antitoxin) |
| Location | 1218290..1218817 | Replicon | chromosome |
| Accession | NZ_CP072455 | ||
| Organism | Xenorhabdus budapestensis strain C-7-2 | ||
Toxin (Protein)
| Gene name | ccdB | Uniprot ID | - |
| Locus tag | HGO23_RS05545 | Protein ID | WP_209028225.1 |
| Coordinates | 1218509..1218817 (+) | Length | 103 a.a. |
Antitoxin (Protein)
| Gene name | ccdA | Uniprot ID | - |
| Locus tag | HGO23_RS05540 | Protein ID | WP_209028224.1 |
| Coordinates | 1218290..1218508 (+) | Length | 73 a.a. |
Genomic Context
Location: 1213349..1213975 (627 bp)
Type: Others
Protein ID: WP_209028221.1
Type: Others
Protein ID: WP_209028221.1
Location: 1215839..1216030 (192 bp)
Type: Others
Protein ID: WP_209028222.1
Type: Others
Protein ID: WP_209028222.1
Location: 1218290..1218508 (219 bp)
Type: Antitoxin
Protein ID: WP_209028224.1
Type: Antitoxin
Protein ID: WP_209028224.1
Location: 1218509..1218817 (309 bp)
Type: Toxin
Protein ID: WP_209028225.1
Type: Toxin
Protein ID: WP_209028225.1
Location: 1220624..1220984 (361 bp)
Type: Others
Protein ID: Protein_1101
Type: Others
Protein ID: Protein_1101
Location: 1221976..1223721 (1746 bp)
Type: Others
Protein ID: WP_209028228.1
Type: Others
Protein ID: WP_209028228.1
Location: 1214492..1215045 (554 bp)
Type: Others
Protein ID: Protein_1093
Type: Others
Protein ID: Protein_1093
Location: 1216088..1217488 (1401 bp)
Type: Others
Protein ID: Protein_1096
Type: Others
Protein ID: Protein_1096
Location: 1217513..1218094 (582 bp)
Type: Others
Protein ID: WP_209028223.1
Type: Others
Protein ID: WP_209028223.1
Location: 1219076..1220578 (1503 bp)
Type: Others
Protein ID: WP_209028226.1
Type: Others
Protein ID: WP_209028226.1
Location: 1221133..1221750 (618 bp)
Type: Others
Protein ID: WP_209028227.1
Type: Others
Protein ID: WP_209028227.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| HGO23_RS05510 (HGO23_05510) | 1213349..1213975 | + | 627 | WP_209028221.1 | TetR/AcrR family transcriptional regulator | - |
| HGO23_RS05515 (HGO23_05515) | 1214492..1215045 | - | 554 | Protein_1093 | conjugative transfer ATPase | - |
| HGO23_RS05525 (HGO23_05525) | 1215839..1216030 | + | 192 | WP_209028222.1 | hypothetical protein | - |
| HGO23_RS05530 (HGO23_05530) | 1216088..1217488 | - | 1401 | Protein_1096 | ISKra4 family transposase | - |
| HGO23_RS05535 (HGO23_05535) | 1217513..1218094 | - | 582 | WP_209028223.1 | recombinase family protein | - |
| HGO23_RS05540 (HGO23_05540) | 1218290..1218508 | + | 219 | WP_209028224.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin |
| HGO23_RS05545 (HGO23_05545) | 1218509..1218817 | + | 309 | WP_209028225.1 | type II toxin-antitoxin system toxin CcdB | Toxin |
| HGO23_RS05550 (HGO23_05550) | 1219076..1220578 | - | 1503 | WP_209028226.1 | Tn3 family transposase | - |
| HGO23_RS05555 (HGO23_05555) | 1220624..1220984 | + | 361 | Protein_1101 | recombinase family protein | - |
| HGO23_RS05560 (HGO23_05560) | 1221133..1221750 | - | 618 | WP_209028227.1 | DJ-1/PfpI family protein | - |
| HGO23_RS05565 (HGO23_05565) | 1221976..1223721 | + | 1746 | WP_209028228.1 | beta-ketoacyl synthase | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 a.a. Molecular weight: 11769.47 Da Isoelectric Point: 5.5740
>T197782 WP_209028225.1 NZ_CP072455:1218509-1218817 [Xenorhabdus budapestensis]
MQFFVYQYKRSGSKYSMFVDVQSDIIETLGRRMVIPLVEAHHFSNKVSNHLFPIVQIKDGNYRLLTTELSSVPESVIGEE
ITDLSQWSSDIKDAINLLFWGI
MQFFVYQYKRSGSKYSMFVDVQSDIIETLGRRMVIPLVEAHHFSNKVSNHLFPIVQIKDGNYRLLTTELSSVPESVIGEE
ITDLSQWSSDIKDAINLLFWGI
Download Length: 309 bp
>T197782 NZ_CP096710:449610-449999 [Acinetobacter baumannii]
TTGATCAACCATTTGAATTTTAAGCTGAAATATAGTCGTTTTTCGATTATATTTCAGTTTTTTATTGGCTTAAGCTTAGC
AGTTCTATTTTATCAATTAATGCCGTTACTATGGTGGTTAGTTGTAATCAGCTTACTATTTATCAGCTTTATTTTCTTTT
TAAAGCGTCCGCAGCTTGCACAAATTGCTTATTTAGATAAAAAACTATGGTCGCTTGCTTATAAGTCACAGAACACCGTT
TCTCGCGTCAAAATTTTAAAAATAATTGATTGTCAGATTTTCATAGTGATCTATTTTGAAGGTCATAAAACACTAACTTC
TATCATTTGGTTTGATCAAATGTCATTAGCAGAGTGGAAAAAGCTTAAAACTTTAGAAAAACTCTATTAA
TTGATCAACCATTTGAATTTTAAGCTGAAATATAGTCGTTTTTCGATTATATTTCAGTTTTTTATTGGCTTAAGCTTAGC
AGTTCTATTTTATCAATTAATGCCGTTACTATGGTGGTTAGTTGTAATCAGCTTACTATTTATCAGCTTTATTTTCTTTT
TAAAGCGTCCGCAGCTTGCACAAATTGCTTATTTAGATAAAAAACTATGGTCGCTTGCTTATAAGTCACAGAACACCGTT
TCTCGCGTCAAAATTTTAAAAATAATTGATTGTCAGATTTTCATAGTGATCTATTTTGAAGGTCATAAAACACTAACTTC
TATCATTTGGTTTGATCAAATGTCATTAGCAGAGTGGAAAAAGCTTAAAACTTTAGAAAAACTCTATTAA
Antitoxin
Download Length: 73 a.a. Molecular weight: 8306.35 Da Isoelectric Point: 7.0108
>AT197782 WP_209028224.1 NZ_CP072455:1218290-1218508 [Xenorhabdus budapestensis]
MKHRVNVTVDKANYLTLSAAGVNISGFINEVMTKEVQRIKAENWKEENRKGMEEVAQFIAQYGSFADENRNW
MKHRVNVTVDKANYLTLSAAGVNISGFINEVMTKEVQRIKAENWKEENRKGMEEVAQFIAQYGSFADENRNW
Download Length: 219 bp
>AT197782 NZ_CP096710:449346-449603 [Acinetobacter baumannii]
ATGTCTGAAGAAATGACCTTGGAAGAACGTAAAGTAATCTATCGCGCACGTCGTGGTTTAAAGGAAATTGATGTCTATTT
TGACCCTTATGTGAAAAATTATTATTTAAAGGCAGACCCGGCAGAAAAAGCGTTGTTTGCTGAGTTGGTAGAACAGGAAG
ACCCTGATTTACTAGATTGGTTTATGGAAGTATCAGAACCACCACGTACCGAATTACGTGACTTTATCTATAAATTAAAA
CACTATGTTCATGGTTAA
ATGTCTGAAGAAATGACCTTGGAAGAACGTAAAGTAATCTATCGCGCACGTCGTGGTTTAAAGGAAATTGATGTCTATTT
TGACCCTTATGTGAAAAATTATTATTTAAAGGCAGACCCGGCAGAAAAAGCGTTGTTTGCTGAGTTGGTAGAACAGGAAG
ACCCTGATTTACTAGATTGGTTTATGGAAGTATCAGAACCACCACGTACCGAATTACGTGACTTTATCTATAAATTAAAA
CACTATGTTCATGGTTAA