Detailed information of TA system TA197779

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /RES-TIGR02293
• Location: 191479..192383
• Replicon: chromosome
• Accession: NZ_CP072455
• Organism: Xenorhabdus budapestensis strain C-7-2

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: HGO23_RS00755
• Protein ID: WP_099135406.1
• Coordinates: 191479..191940 (-)
• Length: 154 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: HGO23_RS00760
• Protein ID: WP_209027616.1
• Coordinates: 191937..192383 (-)
• Length: 149 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HGO23_RS00725 (HGO23_00725)	187258..188091	-	834	WP_099135411.1	rhomboid family intramembrane serine protease GlpG	-
HGO23_RS00730 (HGO23_00730)	188209..188532	-	324	WP_099135410.1	thiosulfate sulfurtransferase GlpE	-
HGO23_RS00735 (HGO23_00735)	188676..189251	-	576	WP_209027614.1	Fe-S biogenesis protein NfuA	-
HGO23_RS00740 (HGO23_00740)	189311..189994	-	684	WP_209027615.1	DNA utilization protein GntX	-
HGO23_RS00745 (HGO23_00745)	190047..190826	+	780	WP_099135408.1	pimeloyl-ACP methyl ester esterase BioH	-
HGO23_RS00750 (HGO23_00750)	190923..191366	-	444	WP_099135407.1	OsmC family protein	-
HGO23_RS00755 (HGO23_00755)	191479..191940	-	462	WP_099135406.1	RES domain-containing protein	Toxin
HGO23_RS00760 (HGO23_00760)	191937..192383	-	447	WP_209027616.1	DUF2384 domain-containing protein	Antitoxin
HGO23_RS00765 (HGO23_00765)	192488..192727	-	240	WP_099135404.1	FeoC-like transcriptional regulator	-
HGO23_RS00770 (HGO23_00770)	192736..195048	-	2313	WP_209028664.1	Fe(2+) transporter permease subunit FeoB	-
HGO23_RS00775 (HGO23_00775)	195113..195343	-	231	WP_038261750.1	ferrous iron transporter A	-
HGO23_RS00780 (HGO23_00780)	195660..196184	-	525	WP_099135403.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (2-148)

Antitoxin

• Antitoxin Xre/MbcA/ParS-like, toxin-binding domain (96-145)

Sequences

Toxin

Protein

• Length: 154 a.a.
• Molecular weight: 17509.78 Da
• Isoelectric Point: 6.4888

>T197779 WP_099135406.1 NZ_CP072455:c191940-191479 [Xenorhabdus budapestensis]
MTFYRLVKSIHANEAWTGYGAKRFGGRWNHKGYHAVYVSSSIALATLELYVHTSKESLLEEYQLFSIELADKNVDYLDHS
YLPDDWRRDPAPVSTMDIGSGWLNAAENVALIIPSCIVPYENNAIINPNHPKFSKSIESVKELNFTFDQRLIR

Nucleotide

• Length: 462 bp

>T197779 NZ_CP096706:60032-60391 [Acinetobacter baumannii]
ATGGCTTGGGATGTAGAAACAACAGAACTTTTTGATTCTTGGTTGGCAGAACAAGATGAAAATGCTCAAGATAAAATCTT
AGCGTCTTTGCTTGTTTTGTCAGAACTGGGGCCAAATCTAGGCCGGCCTCATGTTGATACTATTAAAGAATCAAAATATC
CGAACATGAAAGAGATACGTGTGCAAGTTAAAGGTCATCCGATCCGTGGTTTCTTTGCATTTGATCCAGAACGTAAAGCC
ATTGTTTTGTGTGCTGGAGATAAGAAAGGGCTAAATGAAAAAGCCTTTTATAAAGAAATGATCAAGATTGCAGATGAACA
ATATGAGCAATATTTACGTGATAATTACGGAGATAAATAA

Antitoxin

Protein

• Length: 149 a.a.
• Molecular weight: 16330.69 Da
• Isoelectric Point: 7.3206

>AT197779 WP_209027616.1 NZ_CP072455:c192383-191937 [Xenorhabdus budapestensis]
MRIYVPNDTISKKALWRSVGLPANRGSDLIETLQAGLPLDVLDNLHRDSEISKADILRIAGISERNVARRKSSSRPFSPD
ESERIARLVRVFDAAINFFNGDKEAAYHWLKEPVKGLGNIAPISLISTESGALEVMDLIGRLEHGVIA

Nucleotide

• Length: 447 bp

>AT197779 NZ_CP096706:60391-60690 [Acinetobacter baumannii]
ATGGCTAAATTAAACGATATAATTTCAAAACGCTCACCTGAAAGCCAACAACGCATCAAGAAAATGGCAAATCAAATGCT
ATTGGATATTAACCTCTCGAACTTACGGGAAGAGTTAAAAATATCTCAAGCTGAAATTGCAAAAAATCTAGGTGTAAGCC
AAGCTGCTATTTCAAAACGTGAAAAATTAGGTAAAGATCTTAAGATTTCATCATTAAAAGAATATGTTGAAGCTATGGGT
GGCAAAGTAAGGTTAGATGTTGAGTTACCTAACGGAAAGCATGTTGCGATATCTATTTAA