Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 3391375..3391909 Replicon chromosome
Accession NZ_CP072453
Organism Providencia sp. R33

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag J6836_RS15870 Protein ID WP_219244928.1
Coordinates 3391375..3391665 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag J6836_RS15875 Protein ID WP_219249535.1
Coordinates 3391655..3391909 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J6836_RS15840 (J6836_15845) 3386912..3388204 - 1293 WP_219244925.1 N-acetylmuramoyl-L-alanine amidase AmiB -
J6836_RS15845 (J6836_15850) 3388219..3388683 - 465 WP_219244926.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
J6836_RS15850 (J6836_15855) 3388963..3390144 + 1182 WP_219244927.1 tRNA epoxyqueuosine(34) reductase QueG -
J6836_RS15870 (J6836_15875) 3391375..3391665 - 291 WP_219244928.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
J6836_RS15875 (J6836_15880) 3391655..3391909 - 255 WP_219249535.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
J6836_RS15880 (J6836_15885) 3392036..3392581 - 546 WP_219244929.1 oligoribonuclease -
J6836_RS15885 (J6836_15890) 3392686..3393738 + 1053 WP_219244930.1 small ribosomal subunit biogenesis GTPase RsgA -
J6836_RS15890 (J6836_15895) 3393921..3394817 + 897 WP_219244931.1 archaetidylserine decarboxylase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-84)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-73)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11422.45 Da        Isoelectric Point: 9.9326

>T197776 WP_219244928.1 NZ_CP072453:c3391665-3391375 [Providencia sp. R33]
MIFDIAFDERALREWKKLDCSIREQFKKKLKKLQLNPYIESLRLHGELSNCYKIKLRASGFRLVYQVIDDEIVIFVVAVG
KREDEKVYKSATNRLI

Download         Length: 291 bp

>T197776 NZ_CP096702:1598204-1598386 [Acinetobacter baumannii]
GTGAAAAGTCTGGATTTAATCAAAATGATTGAAGCAGATGGTTGGTATGAGGTTAGGGTTTCAGGAAGTCATCATCACTT
TAAACACCCAACCAAAAAGGGGTTAGTTACAATCCCACATCCTAAAAAGGATTTACCAAACGGAACTGTTAAAAGCATTT
TGAAACAAGCGGGTCTAAATTGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9704.12 Da        Isoelectric Point: 4.8538

>AT197776 WP_219249535.1 NZ_CP072453:c3391909-3391655 [Providencia sp. R33]
MSTIQIRVDEQLKKDAYQAFDKLNLSPSDALRLFLRYVAENEKLPFSEVSIVVSEADEDEDILAVVRNRLKKPAKRIRVN
IDDI

Download         Length: 255 bp

>AT197776 NZ_CP096702:1598479-1598883 [Acinetobacter baumannii]
ATGTTATATCCAATTGCAATTGAACGAGGATCAGATACTGAGGCATTTGGTGTCACTGTTCCTGATATTCCAGGTTGTTT
TAGTGCTGGTGACACACTTGAAGAAGCTATTGAGAATGTTAAAGAAGCTATTTCAGGCCATTTAGAAATATTGGCTGAAG
ATGGTGAGGAAATCCCATTAGCTTCCGAACTAGTTAAATTTGTCGATGATCCTGAATATAAAGGAATGATCTGGGCGGTT
ACCGAAGTTGATGTTAGTCGTTATCTGGGTAAACCAGAAAAAATCAATGTTACTTTACCAAGCCGTTTGATTCGTAAAAT
TGATGAGAATGTAGGTAAAGGTAAGAGATATACTACTCGATCGGCTTTCTTGGCTGCTGGTGCTGAAAAACTTTTACATG
CATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References