Detailed information of TA system TA197768

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): PP_4151-4152/excise(antitoxin)
• Location: 1376704..1377731
• Replicon: chromosome
• Accession: NZ_CP072425
• Organism: Pseudoalteromonas viridis strain BBR56

Toxin (Protein)

• Gene name: PP_4152
• Uniprot ID: -
• Locus tag: J5X90_RS05835
• Protein ID: WP_194866482.1
• Coordinates: 1377162..1377731 (+)
• Length: 190 a.a.

Antitoxin (Protein)

• Gene name: PP_4151
• Uniprot ID: -
• Locus tag: J5X90_RS05830
• Protein ID: WP_194866483.1
• Coordinates: 1376704..1377156 (+)
• Length: 151 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
J5X90_RS05800 (J5X90_05800)	1372059..1372298	+	240	WP_247749621.1	hypothetical protein	-
J5X90_RS05805 (J5X90_05805)	1372549..1374096	+	1548	WP_209053078.1	IS21 family transposase	-
J5X90_RS05810 (J5X90_05810)	1374089..1374844	+	756	WP_194866487.1	IS21-like element helper ATPase IstB	-
J5X90_RS05815 (J5X90_05815)	1374841..1375317	+	477	WP_209053079.1	hypothetical protein	-
J5X90_RS05820 (J5X90_05820)	1375310..1376257	+	948	WP_209053080.1	tyrosine-type recombinase/integrase	-
J5X90_RS05825 (J5X90_05825)	1376325..1376486	+	162	WP_209053081.1	hypothetical protein	-
J5X90_RS05830 (J5X90_05830)	1376704..1377156	+	453	WP_194866483.1	excisionase family DNA-binding protein	Antitoxin
J5X90_RS05835 (J5X90_05835)	1377162..1377731	+	570	WP_194866482.1	PIN domain-containing protein	Toxin
J5X90_RS05840 (J5X90_05840)	1377771..1378922	+	1152	WP_280639027.1	RHS repeat-associated core domain-containing protein	-
J5X90_RS05845 (J5X90_05845)	1378926..1379330	+	405	WP_209053083.1	hypothetical protein	-
J5X90_RS05850 (J5X90_05850)	1379349..1379687	+	339	WP_209053084.1	ribonuclease E inhibitor RraB	-
J5X90_RS05855 (J5X90_05855)	1380030..1380206	+	177	Protein_1128	transposase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	1376325..1387315	10990

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (6-113)

Antitoxin

• SinI-like, DNA-binding domain (80-125)

Sequences

Toxin

Protein

• Length: 190 a.a.
• Molecular weight: 21660.02 Da
• Isoelectric Point: 5.9253

>T197768 WP_194866482.1 NZ_CP072425:1377162-1377731 [Pseudoalteromonas viridis]
MSTYTVILDACVMYPAPLRSYLMHLTLTGLFRARWTEQIHDEWIRNLLLNNPEMDPKKLDRTRQLMNAHVPDCLIEGYEP
LIDGINLPDKDDRHVVAAAVKGQAEGIITFNLKDFPDDKLAPFDLSAIHPDNFLSDMFELDPSAAILAAQRQRRSLKNPP
MTASEYLDCLQRQKLPTLVSHLRKYEAMI

Nucleotide

• Length: 570 bp

>T197768 NZ_CP096693:449904-450293 [Acinetobacter baumannii]
TTGATCAACCATTTGAATTTTAAGCTGAAATATAGTCGTTTTTCGATTATATTTCAGTTTTTTATTGGCTTAAGCTTAGC
AGTTCTATTTTATCAATTAATGCCGTTACTATGGTGGTTAGTTGTAATCAGCTTACTATTTATCAGCTTTATTTTCTTTT
TAAAGCGTCCGCAGCTTGCACAAATTGCTTATTTAGATAAAAAACTATGGTCGCTTGCTTATAAGTCACAGAACACCGTT
TCTCGCGTCAAAATTTTAAAAATAATTGATTGTCAGATTTTCATAGTGATCTATTTTGAAGGTCATAAAACACTAACTTC
TATCATTTGGTTTGATCAAATGTCATTAGCAGAGTGGAAAAAGCTTAAAACTTTAGAAAAACTCTATTAA

Antitoxin

Protein

• Length: 151 a.a.
• Molecular weight: 16417.80 Da
• Isoelectric Point: 4.4682

>AT197768 WP_194866483.1 NZ_CP072425:1376704-1377156 [Pseudoalteromonas viridis]
MLNVKSLPSAEEVALAKLCSQELSAVLEANGEVQELSVVGKDGESHQLKLPASAVQLMIEVLTQLGQGNSVNITPIHAEL
TTQEAADMLNMSRPTLIKILDQGDIPYTRTGNRRKIEFAQVMKYKQDIEAKRLAALDELTDLDQELGLGY

Nucleotide

• Length: 453 bp

>AT197768 NZ_CP096693:449640-449897 [Acinetobacter baumannii]
ATGTCTGAAGAAATGACCTTGGAAGAACGTAAAGTAATCTATCGCGCACGTCGTGGTTTAAAGGAAATTGATGTCTATTT
TGACCCTTATGTGAAAAATTATTATTTAAAGGCAGACCCGGCAGAAAAAGCGTTGTTTGCTGAGTTGGTAGAACAGGAAG
ACCCTGATTTACTAGATTGGTTTATGGAAGTATCAGAACCACCACGTACCGAATTACGTGACTTTATCTATAAATTAAAA
CACTATGTTCATGGTTAA