Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1925895..1926040 Replicon chromosome
Accession NZ_CP072408
Organism Klebsiella pneumoniae strain B4650

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1925931..1926033 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1925895..1926040 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J6316_RS09230 1921025..1923085 + 2061 WP_004151449.1 oligopeptidase B -
J6316_RS09235 1923089..1923748 - 660 WP_002911407.1 exodeoxyribonuclease X -
J6316_RS09240 1923827..1924057 - 231 WP_002911406.1 DNA polymerase III subunit theta -
J6316_RS09245 1924170..1924544 + 375 WP_004151448.1 CopC domain-containing protein YobA -
J6316_RS09250 1924548..1925417 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
J6316_RS09255 1925434..1925772 + 339 WP_002911404.1 YebY family protein -
- 1925895..1926040 - 146 - - Antitoxin
- 1925931..1926033 + 103 - - Toxin
J6316_RS09260 1926409..1926552 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
J6316_RS09265 1926657..1927625 - 969 WP_004151446.1 VirK/YbjX family protein -
J6316_RS09270 1927782..1928435 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
J6316_RS09275 1928432..1928623 - 192 WP_002911395.1 YebW family protein -
J6316_RS09280 1928721..1928960 - 240 WP_002911393.1 YebV family protein -
J6316_RS09285 1929076..1930509 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T197717 NZ_CP072408:1925931-1926033 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT197717 NZ_CP072408:c1926040-1925895 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References