Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/Phd(antitoxin)
Location 66089..66633 Replicon chromosome
Accession NZ_CP072396
Organism Xanthomonas citri pv. fuscans strain 6165R(delta)tal22B

Toxin (Protein)


Gene name relE Uniprot ID A0A808FED4
Locus tag J4T80_RS00270 Protein ID WP_022557812.1
Coordinates 66334..66633 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A828YMS8
Locus tag J4T80_RS00265 Protein ID WP_005912560.1
Coordinates 66089..66346 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J4T80_RS00250 (J4T80_00250) 61192..62691 - 1500 WP_046735535.1 ribonuclease H-like domain-containing protein -
J4T80_RS00255 (J4T80_00255) 62688..65183 - 2496 WP_046832508.1 DEAD/DEAH box helicase -
J4T80_RS00260 (J4T80_00260) 65361..66023 + 663 WP_029818121.1 hemolysin III family protein -
J4T80_RS00265 (J4T80_00265) 66089..66346 + 258 WP_005912560.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
J4T80_RS00270 (J4T80_00270) 66334..66633 + 300 WP_022557812.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
J4T80_RS00280 (J4T80_00280) 66813..67535 - 723 Protein_53 SDR family NAD(P)-dependent oxidoreductase -
J4T80_RS00285 (J4T80_00285) 67595..68575 + 981 WP_007975311.1 IS5-like element ISXfu2 family transposase -
J4T80_RS21615 69182..69427 + 246 WP_223842580.1 GNAT family N-acetyltransferase -
J4T80_RS00295 (J4T80_00295) 69578..70252 + 675 Protein_56 IS5 family transposase -
J4T80_RS00300 (J4T80_00300) 70435..71418 + 984 WP_022557821.1 IS5-like element ISXfu1 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11279.07 Da        Isoelectric Point: 10.1539

>T197691 WP_022557812.1 NZ_CP072396:66334-66633 [Xanthomonas citri pv. fuscans]
MAEIIWSVPALADLDAIADYIAIDNAPAAAALVKRVFAHVEQLIERPDSGSRPQELKRSRYRQIVEPPCRVFYRVDGQRI
VLVHVMRSERALRGNRLSR

Download         Length: 300 bp

>T197691 NZ_CP096583:c2796077-2795829 [Rhodococcus pyridinivorans]
ATGGCTGCCATCACTGCTACCGAAGCGAGGAAAAACTTCTTTCCGCTGCTCGAACAGGTCAACAAGGACCACACCCCTGT
GGAAATCGTATCCAAGCGGGGCAATGCCGTCCTGATGTCGAAGGATGACTACGACGCCATGCTCGAGACCTCGTACCTGA
TGCAGTCTCCGGCCAACGCCCGACGACTGCTCGCCAGCATGCAGAGAGCTCGCGGAGGTGAATACACCGAAAGGGAACTC
ATCGAGTGA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9646.15 Da        Isoelectric Point: 8.6223

>AT197691 WP_005912560.1 NZ_CP072396:66089-66346 [Xanthomonas citri pv. fuscans]
MRTELVTTLKRQATELLAAAERDKEPILITQHGLPSAYLVDVASYERMQQRIALLEGIARGEMAVAEGRTLSHEQAQQRM
ARWLK

Download         Length: 258 bp

>AT197691 NZ_CP096583:c2795832-2795578 [Rhodococcus pyridinivorans]
GTGAACATCACCTTCACCGACGAAGCGTGGGACGACTACCAGTTCTGGATCTCGACCGACAGAAAACAGCTCAAGCGTGT
CAACGAGCTGGTCAGGGATTGCCAACGAGACCCGTACTCGGGGATCGGCAAACCCGAACGGCTCAGACATGCCCTGTCAG
GACTGTGGTCTCGACGTATCGACAAAGAACACCGCCTGGTCTACGAGGTCATCGACGGTGCCCTGGTCATCATCGCCGCC
CGCTACCACTACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A808FED4

Antitoxin

Source ID Structure
AlphaFold DB A0A828YMS8

References