197663

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-DinJ
Location 857930..858479 Replicon chromosome
Accession NZ_CP072380
Organism Atopobium sp. oral taxon 416 strain W9116

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag J4859_RS04765 Protein ID WP_212335137.1
Coordinates 858207..858479 (+) Length 91 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag J4859_RS04760 Protein ID WP_212333420.1
Coordinates 857930..858214 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J4859_RS04715 (J4859_04710) 853116..853271 + 156 WP_212333393.1 hypothetical protein -
J4859_RS04720 (J4859_04715) 853308..853496 + 189 WP_212333396.1 hypothetical protein -
J4859_RS16755 (J4859_04720) 853586..853870 - 285 WP_212333398.1 type II toxin-antitoxin system RelB/DinJ family antitoxin -
J4859_RS04730 (J4859_04725) 854857..855432 + 576 WP_212333403.1 hypothetical protein -
J4859_RS04740 (J4859_04735) 855996..856166 - 171 WP_212333409.1 hypothetical protein -
J4859_RS16760 (J4859_04740) 856153..856623 + 471 WP_212333411.1 hypothetical protein -
J4859_RS04750 (J4859_04745) 856583..857122 + 540 WP_256436822.1 hypothetical protein -
J4859_RS04755 (J4859_04750) 857245..857619 - 375 WP_212333416.1 (2Fe-2S)-binding protein -
J4859_RS04760 (J4859_04755) 857930..858214 + 285 WP_212333420.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
J4859_RS04765 (J4859_04760) 858207..858479 + 273 WP_212335137.1 type II toxin-antitoxin system YafQ family toxin Toxin
J4859_RS04770 (J4859_04765) 858573..858947 - 375 WP_212333416.1 (2Fe-2S)-binding protein -
J4859_RS04775 (J4859_04770) 859262..859408 - 147 WP_212333422.1 hypothetical protein -
J4859_RS04780 (J4859_04775) 859418..859666 - 249 WP_212332887.1 transposase -
J4859_RS04785 (J4859_04780) 859632..860138 - 507 WP_249113801.1 transposase -
J4859_RS16765 860453..860581 - 129 WP_256436823.1 hypothetical protein -
J4859_RS04790 (J4859_04785) 860982..861113 - 132 WP_256436824.1 LysR family transcriptional regulator -
J4859_RS04795 (J4859_04790) 861651..861815 + 165 WP_212333428.1 hypothetical protein -
J4859_RS04800 (J4859_04795) 862071..862418 + 348 WP_212333431.1 hypothetical protein -
J4859_RS04805 (J4859_04800) 862792..862980 + 189 WP_256436857.1 DUF2304 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(3-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(4-75)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10679.22 Da        Isoelectric Point: 7.2789

>T197663 WP_212335137.1 NZ_CP072380:858207-858479 [Atopobium sp. oral taxon 416]
MLEVVPSNQFRKDLKLAKKRGLRISRLKEVVDTLASGQKLDERYRDHNLTGDFRGFRECHIEPDWLLVYRIGEEELELFL
FRTGSHSDLF

Download         Length: 273 bp

>T197663 NZ_CP096539:c1961278-1961126 [Staphylococcus aureus]
ATGTCTAAAGACAAAGATCCAAAATTAAATTATCATGAAGAAGAAAACAGTATGGTAACTGATTTTGAAGATTTAAAAGA
ATTAGGTAAAGAAATGGAACAAATTTCTGATCAAAATGATCAAGAAAAGAATTCTGAAGAAGACAGTCAGTAA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10340.63 Da        Isoelectric Point: 4.6005

>AT197663 WP_212333420.1 NZ_CP072380:857930-858214 [Atopobium sp. oral taxon 416]
MSTANINVRVDADLKRSAEDLFNDLGLNMTAAITMFLKSAVSHDGIPFEVKRVIPNAETKAALAEYDAMKNHPESYKRYS
SFDAMADEVLGNDA

Download         Length: 285 bp

>AT197663 NZ_CP096539:c1961902-1961303 [Staphylococcus aureus]
ATGGCAATGAACTTTAAAGTCTTTGACAATAGTCAACTTGTAGCAGAATATGCTGCTGATATTATTAGAAAGCAATTTAA
CAATAATCCTACTACAATTGCAGGTTTTCATTTAGATACAGATCAAGCGCCAGTACTAGATGAATTAAAGAAAAATGTAG
AAAAACATGCTGTTGATTTTAGCCAAATAAATATTTTAGATTATGACGATAAAAAATCATATTTCGAAGCGTTAGGTGTA
CCAGCAGGTCAAGTTTATCCAATTGCTTATGAAAAAGATGCAATCGAATTAATCGCTGATAAGATTAAAACTAAAGAAAA
TAAAGGGAAATTAACATTACAAGTTGTTTCTATCGATGAACAAGGTAAGTTAAATGTTAGTATTCGTCAAGGACTAATGG
AAGCAAGAGAAATTTTCTTAGTAGTGACTGGTGCTAATAAACGAGATGTAGTTGAAAAATTATATCAAGAAAATGGTAAA
ACAAGCTTTGAACCAGCCGATTTAAAAGCACATAGAATGGTAAATGTTATTCTTGATAAAGAAGCGGCTGCAGGTTTACC
CGAAGATGTTAAAGCTTACTTTACGTCACGCTTTGCTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References