197662

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 847747..848318 Replicon chromosome
Accession NZ_CP072380
Organism Atopobium sp. oral taxon 416 strain W9116

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag J4859_RS04665 Protein ID WP_212333368.1
Coordinates 847747..848019 (-) Length 91 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag J4859_RS04670 Protein ID WP_212333371.1
Coordinates 848043..848318 (-) Length 92 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J4859_RS04635 (J4859_04630) 844023..844541 - 519 WP_212333357.1 FHA domain-containing protein -
J4859_RS04640 (J4859_04635) 844638..845039 - 402 WP_212333360.1 hypothetical protein -
J4859_RS04645 (J4859_04640) 845534..845749 + 216 WP_212333363.1 hypothetical protein -
J4859_RS04650 (J4859_04645) 845718..845908 + 191 Protein_910 transposase -
J4859_RS16070 846540..847418 - 879 Protein_911 LysR family transcriptional regulator -
J4859_RS04665 (J4859_04660) 847747..848019 - 273 WP_212333368.1 type II toxin-antitoxin system YafQ family toxin Toxin
J4859_RS04670 (J4859_04665) 848043..848318 - 276 WP_212333371.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
J4859_RS04675 (J4859_04670) 848890..849363 + 474 WP_212333374.1 flavodoxin -
J4859_RS04680 (J4859_04675) 849430..849918 + 489 WP_212333377.1 hypothetical protein -
J4859_RS04685 (J4859_04680) 849915..850436 + 522 WP_212333380.1 DUF362 domain-containing protein -
J4859_RS04690 (J4859_04685) 850527..850886 - 360 WP_212333383.1 DUF2252 family protein -
J4859_RS04695 (J4859_04690) 851006..851410 - 405 WP_212333385.1 transposase -
J4859_RS16075 851558..851734 - 177 WP_249113758.1 hypothetical protein -
J4859_RS04705 (J4859_04700) 852225..852362 - 138 WP_212329948.1 hypothetical protein -
J4859_RS04710 (J4859_04705) 852796..852987 + 192 Protein_921 transposase -
J4859_RS04715 (J4859_04710) 853116..853271 + 156 WP_212333393.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(3-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(3-66)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10432.74 Da        Isoelectric Point: 5.8995

>T197662 WP_212333368.1 NZ_CP072380:c848019-847747 [Atopobium sp. oral taxon 416]
MPSFRKDIKRLDKKHFDDAPLSEVINLIAENTPEALEELRRHHRMHALAGNWAGSRECHAANAGDWLLIWTSDEEIALME
RTGTHDELFR

Download         Length: 273 bp

>T197662 NZ_CP096539:1591784-1592245 [Staphylococcus aureus]
ATGGGATTATATGAAGAAACTTTAATACAACATGATTATATTGAAATAAGAGAGGCTGATGTGCTTCCAGATAATTTGGA
TGGGGTATGGTTAGGAGATTTAATTTTAATAAAGCGTGGCTTATCAGATAGAGAAAAGGCAGGAATTCTCTTTGAAGAAT
TAGCACATAATAAACTTACATACGGTGATATAGCCGATTACTCGAAATTCAACAATCGCAAGTTCGAAAATTACGCAAGG
CGACACGGCTTTATCTCAGCAGTCCCGTTACGCGAAATTGTGGAAGCTTACAATTATGGTGTACGTAACTTGTATGAGTT
GTCTGAGTATCTGCAATTGAGTGAAGAATACATATTAGAAGCAATAGAACAATATAAAAAGATATATGGTATTGGGACTC
ACTACGGCGAATACTCAATTACATTTGAGCCATTGAGAGTTTTTAAATATAAAGAAATATAA

Antitoxin


Download         Length: 92 a.a.        Molecular weight: 10062.26 Da        Isoelectric Point: 4.8227

>AT197662 WP_212333371.1 NZ_CP072380:c848318-848043 [Atopobium sp. oral taxon 416]
MTTMTIRCDENDKKAAQEVAEYYGFDLSSVTRAFWKQMARTHTIPLNLGNEIPNDGTSAALREGAEIMSRGGTGKSYETA
EDMLAAIRAER

Download         Length: 276 bp

>AT197662 NZ_CP096539:1591448-1591771 [Staphylococcus aureus]
ATGAGAACTTCAGCAGAAATAGGTAAATTAATCAAACAACTACGAAAAGAGAATAATGTGAATTTAACTGATTTTGCAAC
TAAGATAGGTGTCAATAAATCTACCTTATCCCGATATGAAAACGGTAGCAGAAAAATACCTATGGAGGATATAGCTGAAA
TTGCCAATGCATTGAAAGTTACCCCAGAATATTTACTATTAAAAAATAGACAAACAGAAAACGAAGTACAACATCGAGCA
GCTCACCTTGAAGGAGAATTGACAGATGATGAATGGCAAAGAGTTTTAGATTATGCAGATTATATAAGAAGCAAACGTAA
GTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References