Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 320993..321264 Replicon chromosome
Accession NZ_CP072322
Organism Escherichia coli strain EC-JS426

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 321123..321226 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 320993..321264 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J6247_RS01540 317548..318210 - 663 WP_000944256.1 exodeoxyribonuclease X -
J6247_RS01545 318234..318890 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
J6247_RS01550 318992..319222 - 231 WP_000916763.1 DNA polymerase III subunit theta -
J6247_RS01555 319361..319735 + 375 WP_000204699.1 CopC domain-containing protein YobA -
J6247_RS01560 319739..320611 + 873 WP_134159187.1 copper homeostasis membrane protein CopD -
J6247_RS01565 320624..320965 + 342 WP_000976492.1 YebY family protein -
- 320993..321264 - 272 - - Antitoxin
- 321123..321226 + 104 - - Toxin
J6247_RS01570 321361..322017 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
J6247_RS01575 322018..322209 - 192 WP_000457842.1 YebW family protein -
J6247_RS01580 322314..322550 - 237 WP_001295499.1 YebV family protein -
J6247_RS01585 322668..324107 - 1440 WP_024198516.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T197628 NZ_CP072322:321123-321226 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT197628 NZ_CP072322:c321264-320993 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References