Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /BrnT(toxin)
Location 2767462..2767954 Replicon chromosome
Accession NZ_CP072308
Organism Agrobacterium tumefaciens strain 6N2

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag AT6N2_RS13535 Protein ID WP_209087408.1
Coordinates 2767462..2767731 (+) Length 90 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag AT6N2_RS13540 Protein ID WP_209087410.1
Coordinates 2767712..2767954 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AT6N2_RS13505 (AT6N2_C3372) 2763054..2763644 - 591 WP_209087400.1 HupE/UreJ family protein -
AT6N2_RS13510 (AT6N2_C3373) 2763878..2764459 + 582 WP_063950712.1 ATP-dependent Clp protease proteolytic subunit -
AT6N2_RS13515 2764532..2764789 - 258 WP_209087402.1 pentapeptide MXKDX repeat protein -
AT6N2_RS13520 (AT6N2_C3376) 2765008..2765523 + 516 WP_233282506.1 sigma-70 family RNA polymerase sigma factor -
AT6N2_RS13525 (AT6N2_C3377) 2765520..2766164 + 645 WP_209087404.1 NrsF family protein -
AT6N2_RS13530 (AT6N2_C3378) 2766249..2767427 + 1179 WP_209087406.1 benzoate/H(+) symporter BenE family transporter -
AT6N2_RS13535 (AT6N2_C3379) 2767462..2767731 + 270 WP_209087408.1 BrnT family toxin Toxin
AT6N2_RS13540 (AT6N2_C3381) 2767712..2767954 + 243 WP_209087410.1 CopG family antitoxin Antitoxin
AT6N2_RS13545 (AT6N2_C3382) 2768273..2769982 + 1710 WP_063950708.1 2-isopropylmalate synthase -
AT6N2_RS13550 (AT6N2_C3384) 2770182..2771147 - 966 WP_209087412.1 metallophosphoesterase -
AT6N2_RS13555 (AT6N2_C3385) 2771214..2771705 + 492 WP_209087414.1 NUDIX domain-containing protein -
AT6N2_RS13560 (AT6N2_C3386) 2771721..2772713 - 993 WP_209087416.1 glutathione S-transferase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(6-80)

Antitoxin

CopG antitoxin

(8-71)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10775.16 Da        Isoelectric Point: 8.9028

>T197611 WP_209087408.1 NZ_CP072308:2767462-2767731 [Agrobacterium tumefaciens]
MDFELDPAKSESNKDKHGIDFTEARALWLDEKRLVVPLETTSEERYIMIAQLRGKCWSAVYTYRNDRLRVISVRRSRDKE
KQRYEDHQR

Download         Length: 270 bp

>T197611 NZ_CP096272:1212275-1212463 [Staphylococcus aureus]
ATGTCTTTACATTTTGCAATTCTGTTTTGGCTAGCATTAATTTTCTTAGTTGCCGCTACGTTTATACTCGTATTAATGAA
AAAAACTGGCAAAGAATCTAAAAAAGAGTCCTATTTAAGTTTCACTGTCATTCTCTATATTTTTGGATTCGCTATATTAA
TATACACATTTATATTTGGTGTGCTATAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9102.33 Da        Isoelectric Point: 4.8723

>AT197611 WP_209087410.1 NZ_CP072308:2767712-2767954 [Agrobacterium tumefaciens]
MKTISAEDFDKKFDDGEDLDGYIDWSKARRPGLEMVHVDIDLPEKVLRRVDAEAARLGVTRQSLMANWIAERLEIGRGGK

Download         Length: 243 bp

>AT197611 NZ_CP096272:1211986-1212246 [Staphylococcus aureus]
ATGAATAACATTTTGTTAAATGCTATCAATATAGTTATTACTACCACTTTTGTTATCTTTAATATTTTAATCACATATAA
TAAAGATTTAGATGATTTATGTTGGCTCCTGCCTGGTATTATCATTTGTGGTGTGATACTCATCGTATCCTTTACCATTG
CAATGATAACTAAAAACTGGTTAAGTGAAATATTATTTTTTATAAATATCGTACTCGTTCTCTATTACATTTATCCTATT
TTTTATAGTTTTATAGGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References