Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | pasABC/RelE-HTH |
Location | 1437077..1437557 | Replicon | chromosome |
Accession | NZ_CP072308 | ||
Organism | Agrobacterium tumefaciens strain 6N2 |
Toxin (Protein)
Gene name | pasB | Uniprot ID | - |
Locus tag | AT6N2_RS07220 | Protein ID | WP_144575703.1 |
Coordinates | 1437288..1437557 (+) | Length | 90 a.a. |
Antitoxin (Protein)
Gene name | pasA | Uniprot ID | A0A176XG90 |
Locus tag | AT6N2_RS07215 | Protein ID | WP_063947698.1 |
Coordinates | 1437077..1437304 (+) | Length | 76 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
AT6N2_RS07185 | 1432184..1432549 | + | 366 | WP_209089535.1 | hypothetical protein | - |
AT6N2_RS07190 (AT6N2_C1808) | 1432606..1433052 | + | 447 | WP_063947703.1 | DoxX family protein | - |
AT6N2_RS07195 (AT6N2_C1809) | 1433115..1433807 | - | 693 | WP_063947702.1 | ATP phosphoribosyltransferase | - |
AT6N2_RS07200 (AT6N2_C1810) | 1433804..1434928 | - | 1125 | WP_144575698.1 | ATP phosphoribosyltransferase regulatory subunit | - |
AT6N2_RS07205 (AT6N2_C1811) | 1434945..1435313 | - | 369 | WP_144575699.1 | VOC family protein | - |
AT6N2_RS07210 (AT6N2_C1812) | 1435318..1436841 | - | 1524 | WP_209089536.1 | histidine--tRNA ligase | - |
AT6N2_RS07215 (AT6N2_C1813) | 1437077..1437304 | + | 228 | WP_063947698.1 | DUF6290 family protein | Antitoxin |
AT6N2_RS07220 (AT6N2_C1815) | 1437288..1437557 | + | 270 | WP_144575703.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
AT6N2_RS07225 (AT6N2_C1816) | 1437564..1438328 | + | 765 | WP_209089537.1 | hypothetical protein | - |
AT6N2_RS07230 (AT6N2_C1817) | 1438354..1439271 | - | 918 | WP_209089538.1 | LysR family transcriptional regulator | - |
AT6N2_RS07235 (AT6N2_C1819) | 1439353..1440396 | + | 1044 | WP_209089540.1 | YeiH family protein | - |
AT6N2_RS07240 (AT6N2_C1820) | 1440411..1440854 | - | 444 | WP_209089543.1 | hypothetical protein | - |
AT6N2_RS07245 (AT6N2_C1821) | 1440851..1441480 | - | 630 | WP_144575711.1 | DNA-3-methyladenine glycosylase I | - |
AT6N2_RS07250 (AT6N2_C1822) | 1441715..1442491 | + | 777 | WP_209089546.1 | L,D-transpeptidase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 90 a.a. Molecular weight: 10713.39 Da Isoelectric Point: 9.9415
>T197610 WP_144575703.1 NZ_CP072308:1437288-1437557 [Agrobacterium tumefaciens]
VIWTIEYHTLVQKEMRKINPEVRRRIRSFLHERLAALDDPRQTGAALQGSELGNFWRYRVGDYRIICDIQDHKLVVLVVE
IGHRREIYR
VIWTIEYHTLVQKEMRKINPEVRRRIRSFLHERLAALDDPRQTGAALQGSELGNFWRYRVGDYRIICDIQDHKLVVLVVE
IGHRREIYR
Download Length: 270 bp
>T197610 NZ_CP096272:c958949-958698 [Staphylococcus aureus]
ATGAACAACCGCGAACAAATCGAACAATCAGTGATCAGTGCTAGTGCGTATAACGGCAATGACACAGAGGGATTGCTAAA
AGAGATTGAGGACGTTTATAAGAAAGCGCAAGCGTTTGATGAAATACTTGAGGGTTTACCTAATGCTATGCAAGATGCAC
TCAAAGAAGATATTGGTCTTGATGAAGCAGTAGGAATTATGACGGGGCAAGTTGTCTATAAATATGAGGAGGAACAGGAA
AATGAGTATTAG
ATGAACAACCGCGAACAAATCGAACAATCAGTGATCAGTGCTAGTGCGTATAACGGCAATGACACAGAGGGATTGCTAAA
AGAGATTGAGGACGTTTATAAGAAAGCGCAAGCGTTTGATGAAATACTTGAGGGTTTACCTAATGCTATGCAAGATGCAC
TCAAAGAAGATATTGGTCTTGATGAAGCAGTAGGAATTATGACGGGGCAAGTTGTCTATAAATATGAGGAGGAACAGGAA
AATGAGTATTAG
Antitoxin
Download Length: 76 a.a. Molecular weight: 8923.95 Da Isoelectric Point: 4.7254
>AT197610 WP_063947698.1 NZ_CP072308:1437077-1437304 [Agrobacterium tumefaciens]
MSKQTAIRLPDETYERLKALSERTGRTSAYYIREAIEKHIEDMEDLYLAEEATRRIQRGESKVISAEEFWRDLDN
MSKQTAIRLPDETYERLKALSERTGRTSAYYIREAIEKHIEDMEDLYLAEEATRRIQRGESKVISAEEFWRDLDN
Download Length: 228 bp
>AT197610 NZ_CP096272:c958708-958535 [Staphylococcus aureus]
ATGAGTATTAGTGTAGGAGATAAAGTATATAACCATGAAACAAACGAAAGTCTAGAGATTGTGCAATTGGTCGGAGATAT
TAGAGATACACATTATAAACTGTCTGATGATTCAGTTATTAGCATTATAGATTTTATTACTAAACCAATTTATCTAATTA
AGGGGGACGAGTAA
ATGAGTATTAGTGTAGGAGATAAAGTATATAACCATGAAACAAACGAAAGTCTAGAGATTGTGCAATTGGTCGGAGATAT
TAGAGATACACATTATAAACTGTCTGATGATTCAGTTATTAGCATTATAGATTTTATTACTAAACCAATTTATCTAATTA
AGGGGGACGAGTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|