Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relE-yefM/YoeB-RelB
Location 50299..50809 Replicon plasmid p1KSKSensitive
Accession NZ_CP072306
Organism Acinetobacter baumannii strain KSK Sensitive

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag J6I88_RS18615 Protein ID WP_000827770.1
Coordinates 50549..50809 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag J6I88_RS18610 Protein ID WP_001024070.1
Coordinates 50299..50559 (+) Length 87 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J6I88_RS18570 (J6I88_18570) 45705..46373 - 669 WP_000037012.1 HGGxSTG domain-containing protein -
J6I88_RS18575 (J6I88_18575) 46447..46977 - 531 WP_000219384.1 TIGR02594 family protein -
J6I88_RS18580 (J6I88_18580) 46958..47209 - 252 WP_001087198.1 hypothetical protein -
J6I88_RS18585 (J6I88_18585) 47202..47648 - 447 WP_000467408.1 hypothetical protein -
J6I88_RS18590 (J6I88_18590) 47708..48175 - 468 WP_001123866.1 hypothetical protein -
J6I88_RS18595 (J6I88_18595) 48168..48698 - 531 WP_000587898.1 DUF2829 domain-containing protein -
J6I88_RS18600 (J6I88_18600) 48695..49054 - 360 WP_227501444.1 hypothetical protein -
J6I88_RS18605 (J6I88_18605) 49413..49808 - 396 WP_000637615.1 hypothetical protein -
J6I88_RS18610 (J6I88_18610) 50299..50559 + 261 WP_001024070.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
J6I88_RS18615 (J6I88_18615) 50549..50809 + 261 WP_000827770.1 Txe/YoeB family addiction module toxin Toxin
J6I88_RS18620 (J6I88_18620) 50822..51004 + 183 WP_000764644.1 hypothetical protein -
J6I88_RS18625 (J6I88_18625) 51001..51267 - 267 WP_000312809.1 hypothetical protein -
J6I88_RS18630 (J6I88_18630) 51257..51856 - 600 WP_000892963.1 hypothetical protein -
J6I88_RS18635 (J6I88_18635) 51849..52055 - 207 WP_000801902.1 hypothetical protein -
J6I88_RS18640 (J6I88_18640) 52074..52421 - 348 WP_000827933.1 hypothetical protein -
J6I88_RS18645 (J6I88_18645) 52418..52696 - 279 WP_000587223.1 hypothetical protein -
J6I88_RS18650 (J6I88_18650) 52711..52920 - 210 WP_000912547.1 hypothetical protein -
J6I88_RS18655 (J6I88_18655) 52913..53383 - 471 WP_000224739.1 hypothetical protein -
J6I88_RS18660 (J6I88_18660) 53409..53924 - 516 WP_000119773.1 hypothetical protein -
J6I88_RS18665 (J6I88_18665) 53921..54568 - 648 WP_000919094.1 hypothetical protein -
J6I88_RS18670 (J6I88_18670) 54599..54895 - 297 WP_001181556.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..55356 55356


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(7-86)

Antitoxin

(1-73)


Sequences


Toxin        


Download         Length: 87 a.a.        Molecular weight: 10117.52 Da        Isoelectric Point: 8.4866

>T197608 WP_000827770.1 NZ_CP072306:50549-50809 [Acinetobacter baumannii]
MKRNIDFTPTAWDDYLYWQNQDKKTLKRINALIKDCQREPFSGIGKPEGLLGDLSGFWSRRIDEKNRLVYAVDDAAITII
SCRHHY

Download         Length: 261 bp

>T197608 NZ_CP096272:20169-20345 [Staphylococcus aureus]
TTGGATAGGTGGTGGCTATCTGAGTATAAGGAGGTGGTGCCTATGGTGGCATTACTGAAATCTTTAGAAAGGAGACGCCT
AATGATTACAATTAGTACCATGTTGCAGTTTGGTTTATTCCTTATTGCATTGATAGGTCTAGTAATCAAGCTTATTGAAT
TAAGCAATAAAAAATAA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9656.75 Da        Isoelectric Point: 4.4067

>AT197608 WP_001024070.1 NZ_CP072306:50299-50559 [Acinetobacter baumannii]
MNILTYSEARNNLKEVIDQVINDADVTVITRREGQDAVVMGLDHYNSMVETLYLLSNPANSAHLAKSISEYRANKATTRD
LIDDET

Download         Length: 261 bp

>AT197608 NZ_CP096272:c20507-20333 [Staphylococcus aureus]
ATTTGATATTTATATTATGGTGTGTTAATTTATATATAGAAAAAGGGCAACATGCGCAAACATGTTACCCTAGTGAGCCC
GTTAAAAAGACGGTGGCTATTTTAGATTAAAGATTAAATTAATAACCATTTAACCATCGAAACCAGCCAAAGTTAGCGAT
GGTTATTTTTTATTG

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References