Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 5029826..5030187 Replicon chromosome
Accession NZ_CP072265
Organism Xanthomonas citri pv. glycines strain CFBP7119

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag XcgCFBP7119R_RS21905 Protein ID WP_005914328.1
Coordinates 5029826..5029960 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID H8FG64
Locus tag XcgCFBP7119R_RS21910 Protein ID WP_003486606.1
Coordinates 5030035..5030187 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XcgCFBP7119R_RS21885 (XcgCFBP7119R_21885) 5024977..5026668 - 1692 WP_016850771.1 M28 family metallopeptidase -
XcgCFBP7119R_RS21890 (XcgCFBP7119R_21890) 5026860..5027804 - 945 WP_026007158.1 MBL fold metallo-hydrolase -
XcgCFBP7119R_RS21895 (XcgCFBP7119R_21895) 5027933..5029222 - 1290 WP_016850773.1 tryptophan--tRNA ligase -
XcgCFBP7119R_RS21900 (XcgCFBP7119R_21900) 5029390..5029599 - 210 WP_003486601.1 CsbD family protein -
XcgCFBP7119R_RS21905 (XcgCFBP7119R_21905) 5029826..5029960 - 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
XcgCFBP7119R_RS21910 (XcgCFBP7119R_21910) 5030035..5030187 - 153 WP_003486606.1 entericidin A/B family lipoprotein Antitoxin
XcgCFBP7119R_RS21915 (XcgCFBP7119R_21915) 5030294..5031217 - 924 WP_003486608.1 arginase -
XcgCFBP7119R_RS21920 (XcgCFBP7119R_21920) 5031538..5031990 + 453 WP_003486611.1 roadblock/LC7 domain-containing protein -
XcgCFBP7119R_RS21925 (XcgCFBP7119R_21925) 5032054..5032413 + 360 WP_003486613.1 hypothetical protein -
XcgCFBP7119R_RS21930 (XcgCFBP7119R_21930) 5032510..5033427 + 918 WP_016850774.1 hypothetical protein -
XcgCFBP7119R_RS21935 (XcgCFBP7119R_21935) 5033424..5033966 + 543 WP_003486615.1 GTPase -
XcgCFBP7119R_RS21940 (XcgCFBP7119R_21940) 5034404..5035087 + 684 WP_011052674.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T197557 WP_005914328.1 NZ_CP072265:c5029960-5029826 [Xanthomonas citri pv. glycines]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T197557 NZ_CP096243:c58140-57829 [Klebsiella pneumoniae subsp. pneumoniae]
ATGCACGTAATTTCAAAAGAGCCTTTTGAGGAAGCGGCAAAGCGATATCCCAACGATTCGTTAGCCATTCGGGCGTTGTA
CCGCTTAGTGCGCGAGACGGACTTCTCTTCTCCAGCTGAGATGCTAACTCTGATACCGAGCCTGGATAATTTTAAGTACA
GGAATAAGTGGTGGGTTTTGGATGTAGGGGGCAACAACTTAAGGGTTATCGCCTATATCAATTTCGTAAATAAGCGCTTC
TACGTGAAGCACATCGCAACCCACGCTGATTACGACAAGTTGACCCGCTATTACAGGGAGAACAAAGAATGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5122.07 Da        Isoelectric Point: 8.7942

>AT197557 WP_003486606.1 NZ_CP072265:c5030187-5030035 [Xanthomonas citri pv. glycines]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT197557 NZ_CP096243:c57832-57413 [Klebsiella pneumoniae subsp. pneumoniae]
ATGATTACCGACACTGCAAAAGCCATTGAAGCAACCAAACAACTCGTAGCTGCCGTCCCCTTCCTAGGGGGCAGTTCTTC
CGAGAGCGATTACCGCGAAGCGATGGAGCTGGTGGATTATCTGATCGAGAACGACGACGAGAACCCACTTATTGACTTCC
TGGCGAGTAAGATTGCCGACTATGAAGATAACAGCCCTCGTTTCGCTGAGTTCAACAAAGCTATTGCTGAAATACCAGTC
GGCGTTGCACTTCTGCGAACCCTGATTGACCAGCACAAGCTGTCTTATTCAGACCTTAAGGATGAGATCGGATCTAAATC
ATTGGTCAGCCAAATCCTGTCAGGGCAGCGCTCTTTGACCATCACTCACATAAAAGCTCTTTCCGCGCGCTTCGGTGTAA
AACCTGAGTGGTTCCTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6

Antitoxin

Source ID Structure
AlphaFold DB A0A828YLX6

References